KR910005893A - 생조직 등가물 - Google Patents
생조직 등가물 Download PDFInfo
- Publication number
- KR910005893A KR910005893A KR1019900014547A KR900014547A KR910005893A KR 910005893 A KR910005893 A KR 910005893A KR 1019900014547 A KR1019900014547 A KR 1019900014547A KR 900014547 A KR900014547 A KR 900014547A KR 910005893 A KR910005893 A KR 910005893A
- Authority
- KR
- South Korea
- Prior art keywords
- collagen
- wall
- gel
- tissue
- permeable
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
- C12N5/0698—Skin equivalents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/60—Materials for use in artificial skin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
- C12M25/02—Membranes; Filters
- C12M25/04—Membranes; Filters in combination with well or multiwell plates, i.e. culture inserts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/09—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
- C12N2502/094—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells keratinocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
- C12N2502/1323—Adult fibroblasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/54—Collagen; Gelatin
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 본 발명의 기기일부를 해체시킨 실측도이다.
제2도는 제1도의 기기로부터 해체된 부위의 실측도이다.
제3도는 제1도의 기기를 3-3방향으로 전달한 단면도이다.
Claims (19)
- 수축제에 의해 수축된 수화 콜라겐 격자, 및 투과성 요소와 접하고 있는 콜라겐을 함유하는 조직 등가물.
- (a)콜라겐 및 하나 이상의 수축제의 혼합물을 생성시키고, (b) 단계(a)에서 수득된 혼합물을 투과성 요소와 접한 콜라겐 겔에 가한 후, 혼합물 및 겔을 조직 등가물이 형성되도록 하는 조건하에서 유지시킴을 특징으로 하여, 조직 등가물을 제조하는 방법.
- 제2항에 있어서, 수축제가 섬유 아세포를 함유하는 방법.
- 제2항에 있어서, 단계(a)의 혼합물이 약1.25내지 5×104세포수/㎖농도의 섬유 아세포 및 약0.5 내지 2.0mg/㎖농도의 콜라겐을 함유하는 방법.
- 제2항에 있어서, 콜라겐을, 약 0.5 내지 2.0mg/㎖농도의 콜라겐겔을 함유하는 골라켄용액을 캐스팅(casting)시켜 제조하는 방법.
- 제5항에 있어서, 단계(a)의 혼합물 및 단계(b)의 용액을 약3:1 내지 1:3 V/V의 비로 사용하는 방법.
- 제2항에 있어서, 흡착요소가 투과성 요소와 인접하여 존재하는 방법.
- 제7항에 있어서, 흡착요소가 섬유성 패드 또는 겔을 함유하는 방법.
- 제8항에 있어서, 섬유성 패드가 목면인 방법.
- 제2항에 있어서, 아가로즈를 함유하는 겔이 투과성 요소와 인접하여 존재하는 방법.
- 콜라겐 겔(이위에 조직 등가물이 접한다)과 인접한 투과성 요소에 의해 분리되는 제1 및 제2영역(이때, 조직 등가물을 제1영역을 한정하고, 투과성 요소는 제2영역을 한정한다)을 지님을 특징으로 하는 조직등가물 하나 이상을 사용하여 조직 등가물과 하나 이상의 제제 사이의 상호작용을 측정하기 위한 기기.
- 조직 등가물 및 이를 위한 하나 이상의 용기(이때, 용기는 (i) 콜라겐 겔(이위에 조직 등가물이 접한다)과 인접한 투과성 요서(이때, 투과성 요소는 내벽의 바닥을 한정한다)를 지니는 내벽, 및(ii)내벽이 내재하는 외벽을 지닌다)를 포함함을 특징으로 하는, 하나 이사의 조직 등가물을 사용하여 조직과 하나 이상의 제제와의 상호작용을 측정하기 위한 기기.
- 제12항에 있어서, 기기가 용기를 가역적으로 밀폐할수 있는 용기-밀폐용 추가로 포함하는 기기.
- 제12항에 있어서, 내벽에 외벽과의 소통을 위한 개방부 하나 이상이 존재하는 기기.
- 제12항에 있어서, 내벽이 K-수지를 함유하는 기기.
- 제12항에 있어서, 흡착요소가 투과성 요소의 인접하는 기기.
- 제16항에 있어서, 흡착요소가 섬유성 패드 또는 겔을 함유하는 시기.
- 제16항에 있어서, 섬유성 패드가 목면인 기기.
- 제12항에 있어서, 아가로즈 겔이 외용기에 접하는 기기.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US40805289A | 1989-09-15 | 1989-09-15 | |
US07/408,052 | 1989-09-15 | ||
US07/408052 | 1989-09-15 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR910005893A true KR910005893A (ko) | 1991-04-27 |
KR940001379B1 KR940001379B1 (ko) | 1994-02-21 |
Family
ID=23614662
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019900014547A KR940001379B1 (ko) | 1989-09-15 | 1990-09-14 | 생조직 등가물 |
Country Status (12)
Country | Link |
---|---|
US (1) | US5536656A (ko) |
EP (1) | EP0418035B1 (ko) |
JP (1) | JPH03151977A (ko) |
KR (1) | KR940001379B1 (ko) |
AT (1) | ATE119194T1 (ko) |
AU (1) | AU6215690A (ko) |
CA (2) | CA2298856C (ko) |
DE (1) | DE69017324T2 (ko) |
DK (1) | DK0418035T3 (ko) |
ES (1) | ES2071778T3 (ko) |
IE (1) | IE903340A1 (ko) |
IL (1) | IL95429A (ko) |
Families Citing this family (95)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5888720A (en) * | 1992-10-27 | 1999-03-30 | Yissum Research And Development Company Of The Hebrew University Of Jerusalem | In vitro micro-organs |
CA2119064A1 (en) * | 1993-03-17 | 1994-09-18 | Richard A. Berg | Dermal-epidermal in vitro test system |
GB9306449D0 (en) | 1993-03-29 | 1993-05-19 | Nat Heart Research Fund | Tissue equivalents |
CA2188563C (en) | 1994-04-29 | 2005-08-02 | Andrew W. Buirge | Stent with collagen |
US5665114A (en) * | 1994-08-12 | 1997-09-09 | Meadox Medicals, Inc. | Tubular expanded polytetrafluoroethylene implantable prostheses |
US5891558A (en) * | 1994-11-22 | 1999-04-06 | Tissue Engineering, Inc. | Biopolymer foams for use in tissue repair and reconstruction |
US6419920B1 (en) | 1995-10-25 | 2002-07-16 | Trans Karyotic Therapies, Inc. | Hybrid matrix implants and explants |
US5965125A (en) | 1995-10-25 | 1999-10-12 | Transkaryotic Therapies, Inc. | Hybrid matrix implants and explants |
US5955353A (en) * | 1997-05-22 | 1999-09-21 | Excorp Medical, Inc. | Hollow fiber bioreactor with an extrafilament flow plug |
US20020086423A1 (en) * | 1997-09-09 | 2002-07-04 | Toshiaki Takezawa | Hydrogel thin film containing extracellular matrix components |
WO1999046285A2 (en) | 1998-03-11 | 1999-09-16 | University Of Southern California | Method of promoting production of living tissue equivalents |
US6129757A (en) | 1998-05-18 | 2000-10-10 | Scimed Life Systems | Implantable members for receiving therapeutically useful compositions |
CN1333818A (zh) * | 1998-11-19 | 2002-01-30 | 奥加诺吉尼西斯公司 | 生物工程化的组织构建物、其制备方法及其应用 |
US7001746B1 (en) | 1999-01-29 | 2006-02-21 | Artecel Sciences, Inc. | Methods and compositions for the differentiation of human preadipocytes into adipocytes |
US6479072B1 (en) * | 1999-02-11 | 2002-11-12 | The General Hospital Corporation | Microfabricated membranes and matrices |
US6197061B1 (en) * | 1999-03-01 | 2001-03-06 | Koichi Masuda | In vitro production of transplantable cartilage tissue cohesive cartilage produced thereby, and method for the surgical repair of cartilage damage |
WO2000078932A1 (en) | 1999-06-21 | 2000-12-28 | The General Hospital Corporation | Cell culture systems and methods for organ assist devices |
WO2001014527A1 (en) * | 1999-08-23 | 2001-03-01 | Organogenesis Inc. | Skin care compositions and treatments |
JP2003523767A (ja) * | 2000-02-26 | 2003-08-12 | アーテイセル・サイエンスイーズ・インコーポレイテツド | 脂肪組織由来の間質細胞から生成した多能性幹細胞およびその用途 |
US7582292B2 (en) | 2000-02-26 | 2009-09-01 | Artecel, Inc. | Adipose tissue derived stromal cells for the treatment of neurological disorders |
EP1918366A1 (en) | 2000-02-26 | 2008-05-07 | Artecel, Inc. | Pleuripotent stem cells generated from adipose tissue-derived stromal cells and uses thereof |
EP1290144A2 (de) * | 2000-05-31 | 2003-03-12 | Fraunhofer-Gesellschaft Zur Förderung Der Angewandten Forschung E.V. | In vitro-gewebetestsystem |
ATE308610T1 (de) | 2000-05-31 | 2005-11-15 | Fraunhofer Ges Forschung | Dreidimensionales hautmodell |
US7144729B2 (en) | 2000-09-01 | 2006-12-05 | Dfb Pharmaceuticals, Inc. | Methods and compositions for tissue regeneration |
MXPA03002415A (es) | 2000-09-18 | 2004-07-08 | Organogenesis Inc | Metodo para tratar a un paciente que utiliza una construccion de tejido conectivo cultivado. |
EP1832300A3 (en) * | 2000-09-18 | 2008-02-27 | Organogenesis Inc. | Method for treating a patient using a cultured connective tissue construct |
US7041868B2 (en) | 2000-12-29 | 2006-05-09 | Kimberly-Clark Worldwide, Inc. | Bioabsorbable wound dressing |
US6974697B2 (en) * | 2001-03-02 | 2005-12-13 | Stratech Corporation | Skin substitutes with improved barrier function |
US7501238B2 (en) * | 2001-03-02 | 2009-03-10 | Allen Comer | Skin substitutes for irritancy testing |
US20030211793A1 (en) * | 2001-03-05 | 2003-11-13 | Eugene Bell | Injectable bio-compatible material and methods of use |
ES2370165T3 (es) | 2001-06-14 | 2011-12-13 | Millipore Corporation | Bandeja con protuberancias. |
EP1435980A4 (en) * | 2001-09-15 | 2006-06-07 | Univ California | LAMINATED CARTILAGINOUS FABRIC AND MANUFACTURING METHOD THEREOF |
US20030165473A1 (en) * | 2001-11-09 | 2003-09-04 | Rush-Presbyterian-St. Luke's Medical Center | Engineered intervertebral disc tissue |
WO2003072128A2 (en) * | 2002-02-22 | 2003-09-04 | Ebi, L.P. | Methods and compositions for treating bone or cartilage defects |
US7741116B2 (en) | 2002-03-06 | 2010-06-22 | University Of Cincinnati | Surgical device for skin therapy or testing |
US7498167B2 (en) * | 2002-04-30 | 2009-03-03 | Allen Comer | Keratinocytes expressing exogenous angiogenic growth factors |
US7229820B2 (en) * | 2002-06-13 | 2007-06-12 | Wilson Wolf Manufacturing Corporation | Apparatus and method for culturing and preserving tissue constructs |
US7462448B2 (en) * | 2002-08-02 | 2008-12-09 | Stratatech Corporation | Species specific DNA detection |
JP4734245B2 (ja) | 2003-08-01 | 2011-07-27 | ストラタテック コーポレーション | 外因性ポリペプチドを発現するヒト皮膚等価物 |
FR2881434B1 (fr) * | 2005-02-02 | 2007-05-11 | Coletica Sa | Dispositif de support de culture de cellules |
EP1858333B1 (en) | 2005-03-01 | 2015-12-23 | Stratatech Corporation | Human skin equivalents expressing exogenous polypeptides |
US9295543B2 (en) | 2005-03-17 | 2016-03-29 | Stratatech Corporation | Skin substitutes with improved purity |
FR2889808B1 (fr) | 2005-08-17 | 2011-07-22 | Oreal | Utilisation de l'acide 8-hexadecene-1,16-dicarboxylique comme agent de soin destine a favoriser la cohesion de la couche cornee |
CN101489395A (zh) * | 2006-03-03 | 2009-07-22 | 器官发生有限公司 | 口腔组织再生和修复 |
FR2903702B1 (fr) | 2006-07-13 | 2012-10-19 | Oreal | Equivalent d'epiderme capable de se pigmenter obtenu a partir de cellules de la matrice, procede de preparation et utilisation |
US8932619B2 (en) * | 2007-06-27 | 2015-01-13 | Sofradim Production | Dural repair material |
US20090068250A1 (en) * | 2007-09-07 | 2009-03-12 | Philippe Gravagna | Bioresorbable and biocompatible compounds for surgical use |
WO2009043052A1 (en) * | 2007-09-27 | 2009-04-02 | Columbia University | Methods and systems for forming biocompatible materials |
PT2215212T (pt) | 2007-11-14 | 2017-12-01 | Stratatech Corp | Armazenamento a frio de equivalentes de pele cultivados de forma organotípica para aplicações clínicas |
US9308068B2 (en) | 2007-12-03 | 2016-04-12 | Sofradim Production | Implant for parastomal hernia |
US9095569B2 (en) | 2008-04-18 | 2015-08-04 | Collplant Ltd. | Methods of generating and using procollagen |
WO2009156866A2 (en) | 2008-06-27 | 2009-12-30 | Sofradim Production | Biosynthetic implant for soft tissue repair |
EP2350259A4 (en) * | 2008-10-22 | 2013-12-18 | Regenemed Inc | CULTURE SYSTEMS |
US8580314B2 (en) | 2008-11-04 | 2013-11-12 | Stratatech Corporation | Dried and irradiated skin equivalents for ready use |
US9511093B2 (en) * | 2009-03-23 | 2016-12-06 | The Texas A & M University System | Compositions of mesenchymal stem cells to regenerate bone |
WO2010135655A2 (en) * | 2009-05-21 | 2010-11-25 | Stratatech Corporation | Human skin substitutes expressing il-12 |
US9321988B2 (en) * | 2009-06-18 | 2016-04-26 | Illinois Tool Works Inc. | Gas and liquid tissue culture interface |
FR2949688B1 (fr) | 2009-09-04 | 2012-08-24 | Sofradim Production | Tissu avec picots revetu d'une couche microporeuse bioresorbable |
CN102883796B (zh) * | 2010-04-05 | 2016-04-06 | Emd密理博公司 | 具有类似人类皮肤的渗透性的聚合物膜及其用途 |
FR2967163A1 (fr) | 2010-11-05 | 2012-05-11 | Centre Nat Rech Scient | Procede in vitro ou ex vivo pour la maintenance en survie et la generation ou reconstruction d'un epiderme |
FR2972626B1 (fr) | 2011-03-16 | 2014-04-11 | Sofradim Production | Prothese comprenant un tricot tridimensionnel et ajoure |
FR2976001B1 (fr) | 2011-05-30 | 2014-10-31 | Oreal | Modele de cuir chevelu reconstruit et procede de screening de molecules actives |
FR2977790B1 (fr) | 2011-07-13 | 2013-07-19 | Sofradim Production | Prothese pour hernie ombilicale |
FR2977789B1 (fr) | 2011-07-13 | 2013-07-19 | Sofradim Production | Prothese pour hernie ombilicale |
CA2847615A1 (en) | 2011-09-30 | 2013-04-04 | Sofradim Production | Multilayer implants for delivery of therapeutic agents |
AU2012313984B2 (en) | 2011-09-30 | 2016-02-11 | Covidien Lp | Reversible stiffening of light weight mesh |
FR2985271B1 (fr) | 2011-12-29 | 2014-01-24 | Sofradim Production | Tricot a picots |
FR2985170B1 (fr) | 2011-12-29 | 2014-01-24 | Sofradim Production | Prothese pour hernie inguinale |
FR2994185B1 (fr) | 2012-08-02 | 2015-07-31 | Sofradim Production | Procede de preparation d’une couche poreuse a base de chitosane |
PL226837B1 (pl) | 2012-08-24 | 2017-09-29 | Celther Polska Spółka Z Ograniczoną Odpowiedzialnością | Aktywna warstwa polimerowa utworzona zpochodnych chityny zwłaszcza doopatrunku oraz jejzastosowanie |
FR2995788B1 (fr) | 2012-09-25 | 2014-09-26 | Sofradim Production | Patch hemostatique et procede de preparation |
FR2995778B1 (fr) | 2012-09-25 | 2015-06-26 | Sofradim Production | Prothese de renfort de la paroi abdominale et procede de fabrication |
FR2995779B1 (fr) | 2012-09-25 | 2015-09-25 | Sofradim Production | Prothese comprenant un treillis et un moyen de consolidation |
EP2900174B1 (en) | 2012-09-28 | 2017-04-12 | Sofradim Production | Packaging for a hernia repair device |
CA3071928A1 (en) | 2013-03-13 | 2014-10-02 | Stratatech Corporation | Cryopreservation of viable human skin substitutes |
US10478526B2 (en) | 2013-05-03 | 2019-11-19 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Skin substitutes and methods for hair follicle neogenesis |
FR3006581B1 (fr) | 2013-06-07 | 2016-07-22 | Sofradim Production | Prothese a base d’un textile pour voie laparoscopique |
FR3006578B1 (fr) | 2013-06-07 | 2015-05-29 | Sofradim Production | Prothese a base d’un textile pour voie laparoscopique |
WO2015166455A1 (en) | 2014-04-30 | 2015-11-05 | Fondazione Istituto Italiano Di Tecnologia | Method for producing a totally endogenous bioengineered tissue and tissue obtained thereby |
EP3000489B1 (en) | 2014-09-24 | 2017-04-05 | Sofradim Production | Method for preparing an anti-adhesion barrier film |
EP3000433B1 (en) | 2014-09-29 | 2022-09-21 | Sofradim Production | Device for introducing a prosthesis for hernia treatment into an incision and flexible textile based prosthesis |
EP3000432B1 (en) | 2014-09-29 | 2022-05-04 | Sofradim Production | Textile-based prosthesis for treatment of inguinal hernia |
EP3029189B1 (en) | 2014-12-05 | 2021-08-11 | Sofradim Production | Prosthetic porous knit, method of making same and hernia prosthesis |
EP3059255B1 (en) | 2015-02-17 | 2020-05-13 | Sofradim Production | Method for preparing a chitosan-based matrix comprising a fiber reinforcement member |
EP3085337B1 (en) | 2015-04-24 | 2022-09-14 | Sofradim Production | Prosthesis for supporting a breast structure |
EP3106185B1 (en) | 2015-06-19 | 2018-04-25 | Sofradim Production | Synthetic prosthesis comprising a knit and a non porous film and method for forming same |
EP3195830B1 (en) | 2016-01-25 | 2020-11-18 | Sofradim Production | Prosthesis for hernia repair |
FR3054449B1 (fr) | 2016-07-29 | 2018-08-31 | L'oreal | Equivalent de peau a compartiments dermiques juxtaposes distincts |
EP3312325B1 (en) | 2016-10-21 | 2021-09-22 | Sofradim Production | Method for forming a mesh having a barbed suture attached thereto and the mesh thus obtained |
EP3398554A1 (en) | 2017-05-02 | 2018-11-07 | Sofradim Production | Prosthesis for inguinal hernia repair |
WO2018220137A1 (en) * | 2017-05-31 | 2018-12-06 | ETH Zürich | Assembly for the production of tissue implants |
FR3071512B1 (fr) | 2017-09-28 | 2022-02-25 | Oreal | Signatures moleculaires de trois sous-populations de fibroblastes dermiques et equivalent de derme comprenant une de ces sous-populations |
EP3653171A1 (en) | 2018-11-16 | 2020-05-20 | Sofradim Production | Implants suitable for soft tissue repair |
FR3111904B1 (fr) | 2020-06-30 | 2022-10-21 | Oreal | Bioencre pour bioimpression d’un modèle de jonction dermo-épidermique invaginée |
LU502391B1 (en) | 2022-06-28 | 2024-01-09 | Univerza V Mariboru | A complex in vitro model of human skin, a process for preparation and use thereof |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2677646A (en) * | 1952-03-22 | 1954-05-04 | Lovell Chemical Company | Unit for bacterial analysis |
US2761813A (en) * | 1953-01-21 | 1956-09-04 | Goetz Alexander | Means and method of producing and controlling cultures of microorganisms |
GB1594389A (en) * | 1977-06-03 | 1981-07-30 | Max Planck Gesellschaft | Dressing material for wounds |
JPS55501130A (ko) * | 1978-12-26 | 1980-12-18 | ||
US4290911A (en) * | 1979-02-07 | 1981-09-22 | Fmc Corporation | Agarose composition, aqueous gel and method of making same |
SE7908454L (sv) * | 1979-10-11 | 1981-04-12 | Pharmacia Fine Chemicals Ab | Medium for isoelektrisk fokusering |
US4539716A (en) * | 1981-03-19 | 1985-09-10 | Massachusetts Institute Of Technology | Fabrication of living blood vessels and glandular tissues |
US4546500A (en) * | 1981-05-08 | 1985-10-15 | Massachusetts Institute Of Technology | Fabrication of living blood vessels and glandular tissues |
US4505266A (en) * | 1981-10-26 | 1985-03-19 | Massachusetts Institute Of Technology | Method of using a fibrous lattice |
US4485096A (en) * | 1982-02-26 | 1984-11-27 | Massachusetts Institute Of Technology | Tissue-equivalent and method for preparation thereof |
US4485097A (en) * | 1982-05-26 | 1984-11-27 | Massachusetts Institute Of Technology | Bone-equivalent and method for preparation thereof |
US4598045A (en) * | 1982-08-25 | 1986-07-01 | Hana Biologics, Inc. | Triphasic mycoplasmatales detection method |
US4734372A (en) * | 1983-02-04 | 1988-03-29 | Brown University Research Foundation | Cell culturing methods and apparatus |
US4578354A (en) * | 1983-05-09 | 1986-03-25 | Pfizer Inc. | Immobilization of catalytically active microorganisms in agar gel fibers |
DE3584188D1 (de) * | 1984-05-11 | 1991-10-31 | Terumo Corp | Verfahren zur herstellung eines behaelters aus syntetischem harz. |
US4604346A (en) * | 1984-10-09 | 1986-08-05 | Massachusetts Institute Of Technology | Skin-equivalent prepared by the use of punch biopsy |
JPS6225974A (ja) * | 1985-07-25 | 1987-02-03 | Asahi Chem Ind Co Ltd | コラ−ゲンよりなるゲル状組成物 |
US5026649A (en) * | 1986-03-20 | 1991-06-25 | Costar Corporation | Apparatus for growing tissue cultures in vitro |
US4963489A (en) * | 1987-04-14 | 1990-10-16 | Marrow-Tech, Inc. | Three-dimensional cell and tissue culture system |
US5032508A (en) * | 1988-09-08 | 1991-07-16 | Marrow-Tech, Inc. | Three-dimensional cell and tissue culture system |
US5037656A (en) * | 1986-12-04 | 1991-08-06 | Millipore Corporation | Porous membrane having hydrophilic and cell growth promotions surface and process |
FR2612939B1 (fr) * | 1987-03-26 | 1989-06-23 | Cird | Equivalent de peau |
FR2612938B1 (fr) * | 1987-03-26 | 1989-06-23 | Cird | Procede d'obtention d'un equivalent de peau et equivalent de peau correspondant |
US4835102A (en) * | 1987-03-31 | 1989-05-30 | Eugene Bell | Tissue equivalent test systems |
US4837379A (en) * | 1988-06-02 | 1989-06-06 | Organogenesis Inc. | Fibrin-collagen tissue equivalents and methods for preparation thereof |
US4996154A (en) * | 1989-05-04 | 1991-02-26 | Millipore Corporation | Method for growing cellular tissue |
US4912057A (en) * | 1989-06-13 | 1990-03-27 | Cancer Diagnostics, Inc. | Cell chamber for chemotaxis assay |
-
1990
- 1990-08-20 IL IL95429A patent/IL95429A/xx not_active IP Right Cessation
- 1990-08-24 CA CA002298856A patent/CA2298856C/en not_active Expired - Fee Related
- 1990-08-24 CA CA002023968A patent/CA2023968C/en not_active Expired - Fee Related
- 1990-09-05 AU AU62156/90A patent/AU6215690A/en not_active Abandoned
- 1990-09-11 DE DE69017324T patent/DE69017324T2/de not_active Expired - Lifetime
- 1990-09-11 DK DK90309942.2T patent/DK0418035T3/da active
- 1990-09-11 ES ES90309942T patent/ES2071778T3/es not_active Expired - Lifetime
- 1990-09-11 EP EP90309942A patent/EP0418035B1/en not_active Expired - Lifetime
- 1990-09-11 AT AT90309942T patent/ATE119194T1/de not_active IP Right Cessation
- 1990-09-14 IE IE334090A patent/IE903340A1/en not_active IP Right Cessation
- 1990-09-14 JP JP2246000A patent/JPH03151977A/ja active Granted
- 1990-09-14 KR KR1019900014547A patent/KR940001379B1/ko not_active IP Right Cessation
-
1994
- 1994-02-09 US US08/193,809 patent/US5536656A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2023968A1 (en) | 1991-03-16 |
CA2298856A1 (en) | 1991-03-16 |
DE69017324T2 (de) | 1995-08-03 |
JPH03151977A (ja) | 1991-06-28 |
CA2298856C (en) | 2004-11-16 |
EP0418035A1 (en) | 1991-03-20 |
DK0418035T3 (da) | 1995-07-10 |
IL95429A (en) | 1997-09-30 |
KR940001379B1 (ko) | 1994-02-21 |
US5536656A (en) | 1996-07-16 |
IE903340A1 (en) | 1991-04-10 |
ATE119194T1 (de) | 1995-03-15 |
AU6215690A (en) | 1991-08-01 |
ES2071778T3 (es) | 1995-07-01 |
IL95429A0 (en) | 1991-06-30 |
JPH0553505B2 (ko) | 1993-08-10 |
DE69017324D1 (de) | 1995-04-06 |
EP0418035B1 (en) | 1995-03-01 |
CA2023968C (en) | 2000-05-02 |
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