JPH0446950B2 - - Google Patents

Info

Publication number
JPH0446950B2
JPH0446950B2 JP59271603A JP27160384A JPH0446950B2 JP H0446950 B2 JPH0446950 B2 JP H0446950B2 JP 59271603 A JP59271603 A JP 59271603A JP 27160384 A JP27160384 A JP 27160384A JP H0446950 B2 JPH0446950 B2 JP H0446950B2
Authority
JP
Japan
Prior art keywords
hydroxy
compound
methylethyl
methoxyphenyl
ethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP59271603A
Other languages
English (en)
Japanese (ja)
Other versions
JPS60208965A (ja
Inventor
Takeo Iwakuma
Akira Tsunashima
Ichiro Ikezawa
Takeyuki Takaichi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Tanabe Pharma Corp
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Publication of JPS60208965A publication Critical patent/JPS60208965A/ja
Publication of JPH0446950B2 publication Critical patent/JPH0446950B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C07D207/48—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/58—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems with hetero atoms directly attached to the ring nitrogen atom
    • C07D215/60—N-oxides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP59271603A 1983-12-24 1984-12-21 新規カルボスチリル誘導体及びその製法 Granted JPS60208965A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB838334494A GB8334494D0 (en) 1983-12-24 1983-12-24 Carbostyril derivatives
GB8334494 1983-12-24

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP62132886A Division JPS6354362A (ja) 1983-12-24 1987-05-28 カルボスチリル化合物

Publications (2)

Publication Number Publication Date
JPS60208965A JPS60208965A (ja) 1985-10-21
JPH0446950B2 true JPH0446950B2 (forum.php) 1992-07-31

Family

ID=10553866

Family Applications (2)

Application Number Title Priority Date Filing Date
JP59271603A Granted JPS60208965A (ja) 1983-12-24 1984-12-21 新規カルボスチリル誘導体及びその製法
JP62132886A Pending JPS6354362A (ja) 1983-12-24 1987-05-28 カルボスチリル化合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP62132886A Pending JPS6354362A (ja) 1983-12-24 1987-05-28 カルボスチリル化合物

Country Status (10)

Country Link
US (2) US4579854A (forum.php)
EP (1) EP0147719B1 (forum.php)
JP (2) JPS60208965A (forum.php)
AT (1) ATE44954T1 (forum.php)
CA (1) CA1258859A (forum.php)
DE (1) DE3479119D1 (forum.php)
GB (1) GB8334494D0 (forum.php)
HK (1) HK89790A (forum.php)
MY (1) MY101891A (forum.php)
SG (1) SG75290G (forum.php)

Families Citing this family (85)

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US4677112A (en) * 1984-02-02 1987-06-30 Warner-Lambert Company 1,2,3,4-tetrahydro-2-oxo-8-quinolineacetic and -propanoic acids and derivatives as cognition activators
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EP0674515B1 (en) * 1993-10-21 1999-09-22 Otsuka Pharmaceutical Co., Ltd. The use of carbostyril derivatives for the preparation of a medicament for the inhibition of Interleukin-8
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WO1998041193A1 (en) 1997-03-20 1998-09-24 Schering Corporation Preparation of powder agglomerates
US20010031244A1 (en) 1997-06-13 2001-10-18 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
DZ2947A1 (fr) * 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
US6315985B1 (en) * 1999-06-18 2001-11-13 3M Innovative Properties Company C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability
US7214687B2 (en) * 1999-07-14 2007-05-08 Almirall Ag Quinuclidine derivatives and medicinal compositions containing the same
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BRPI0807913A2 (pt) * 2007-02-15 2014-06-17 Argenta Discovery Ltd Derivado heterocíclicos como receptores muscarínicos m3
US8236959B2 (en) * 2007-02-28 2012-08-07 Cipla Limited Process for preparing isomers of carmoterol
CA2608561A1 (en) * 2007-10-29 2009-04-29 Carl Paluszkiewicz Motorcycle wind deflector accessory support
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JP5584138B2 (ja) 2008-01-11 2014-09-03 ノバルティス アーゲー キナーゼ阻害剤としてのピリミジン類
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WO2011136753A1 (en) 2010-04-26 2011-11-03 Mahmut Bilgic Combination of carmoterol and fluticasone for use in the treatment respiratory diseases
WO2011136752A1 (en) 2010-04-26 2011-11-03 Mahmut Bilgic Combined pharmaceutical composition comprising carmoterol and ciclesonide for the treatment of respiratory diseases
WO2011136754A1 (en) 2010-04-26 2011-11-03 Mahmut Bilgic A medicament developed for the treatment of respiratory diseases
WO2012034095A1 (en) 2010-09-09 2012-03-15 Irm Llc Compounds and compositions as trk inhibitors
US8637516B2 (en) 2010-09-09 2014-01-28 Irm Llc Compounds and compositions as TRK inhibitors
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MA34969B1 (fr) 2011-02-25 2014-03-01 Irm Llc Composes et compositions en tant qu inibiteurs de trk
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WO2013011999A1 (ja) * 2011-07-20 2013-01-24 株式会社カネカ 光学活性２－メチルプロリン誘導体の製造法
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WO2013077830A1 (en) 2011-11-25 2013-05-30 Mahmut Bilgic Synergistilly active combinations of roflumilast and carmoterol
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CZ306252B6 (cs) * 2013-03-15 2016-10-26 Zentiva, K.S. Způsob přípravy 5-[(R)-2-(5,6-diethylindan-2-ylamino)-1-hydroxyethyl]-8-hydroxy-(1H)-chinolin-2-onu (indacaterolu)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE354279B (forum.php) * 1969-06-13 1973-03-05 Draco Ab
JPS5156464A (ja) * 1974-11-11 1976-05-18 Otsuka Pharma Co Ltd Karubosuchirirujudotaino seizoho
US4022776A (en) * 1974-01-31 1977-05-10 Otsuka Pharmaceutical Company Limited 5-[1-Hydroxy-2-(substituted-amino)]ethyl-8-hydroxycarbostyril derivatives
JPS6026784B2 (ja) * 1975-04-29 1985-06-25 樋口 佳成 新規カルボスチリル誘導体
JPS52283A (en) * 1975-06-23 1977-01-05 Otsuka Pharmaceut Co Ltd Process for preparation of carbostyril derivatives
JPS5913510B2 (ja) * 1975-12-26 1984-03-30 オオツカセイヤク カブシキガイシヤ カルボスチリルユウドウタイノセイゾウホウ
JPS609713B2 (ja) * 1976-10-08 1985-03-12 大塚製薬株式会社 カルボスチリル誘導体
JPS5913510A (ja) * 1982-07-14 1984-01-24 Kotobuki Sangyo Kk 冷却誘導案内装置

Also Published As

Publication number Publication date
EP0147719A3 (en) 1986-06-25
JPS6354362A (ja) 1988-03-08
DE3479119D1 (en) 1989-08-31
JPS60208965A (ja) 1985-10-21
SG75290G (en) 1990-11-23
EP0147719A2 (en) 1985-07-10
CA1259074C (forum.php) 1989-09-05
ATE44954T1 (de) 1989-08-15
EP0147719B1 (en) 1989-07-26
US4579854A (en) 1986-04-01
MY101891A (en) 1992-02-15
USRE33024E (en) 1989-08-15
GB8334494D0 (en) 1984-02-01
HK89790A (en) 1990-11-09
CA1258859A (en) 1989-08-29

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