JPH0427984B2 - - Google Patents

Info

Publication number
JPH0427984B2
JPH0427984B2 JP58066854A JP6685483A JPH0427984B2 JP H0427984 B2 JPH0427984 B2 JP H0427984B2 JP 58066854 A JP58066854 A JP 58066854A JP 6685483 A JP6685483 A JP 6685483A JP H0427984 B2 JPH0427984 B2 JP H0427984B2
Authority
JP
Japan
Prior art keywords
structural formula
compound
toxic salts
imidazoline
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP58066854A
Other languages
English (en)
Japanese (ja)
Other versions
JPS58192882A (ja
Inventor
Robin Suteiruringusu Maikeru
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Reckitt Benckiser Healthcare UK Ltd
Original Assignee
Reckitt and Colman Products Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reckitt and Colman Products Ltd filed Critical Reckitt and Colman Products Ltd
Publication of JPS58192882A publication Critical patent/JPS58192882A/ja
Publication of JPH0427984B2 publication Critical patent/JPH0427984B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/12—1,4-Dioxanes; Hydrogenated 1,4-dioxanes not condensed with other rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Lock And Its Accessories (AREA)
  • Vehicle Interior And Exterior Ornaments, Soundproofing, And Insulation (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Paper (AREA)
  • Inks, Pencil-Leads, Or Crayons (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
JP58066854A 1982-04-17 1983-04-15 イミダゾリン誘導体 Granted JPS58192882A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB11205 1982-04-17
GB8211205 1982-04-17

Publications (2)

Publication Number Publication Date
JPS58192882A JPS58192882A (ja) 1983-11-10
JPH0427984B2 true JPH0427984B2 (en, 2012) 1992-05-13

Family

ID=10529762

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58066854A Granted JPS58192882A (ja) 1982-04-17 1983-04-15 イミダゾリン誘導体

Country Status (24)

Country Link
US (1) US4446148A (en, 2012)
EP (1) EP0092328B1 (en, 2012)
JP (1) JPS58192882A (en, 2012)
AT (1) ATE27275T1 (en, 2012)
AU (1) AU552397B2 (en, 2012)
CA (1) CA1190932A (en, 2012)
CS (1) CS233746B2 (en, 2012)
DD (1) DD209628A5 (en, 2012)
DE (1) DE3371631D1 (en, 2012)
DK (1) DK160093C (en, 2012)
ES (1) ES521440A0 (en, 2012)
FI (1) FI73676C (en, 2012)
GB (1) GB2118548B (en, 2012)
GR (1) GR78528B (en, 2012)
HU (1) HU190894B (en, 2012)
IE (1) IE54922B1 (en, 2012)
IL (1) IL68318A (en, 2012)
NO (1) NO158019C (en, 2012)
NZ (1) NZ203680A (en, 2012)
PL (1) PL143658B1 (en, 2012)
PT (1) PT76558B (en, 2012)
SU (1) SU1217257A3 (en, 2012)
ZA (1) ZA832278B (en, 2012)
ZW (1) ZW8783A1 (en, 2012)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4882343A (en) * 1987-08-28 1989-11-21 G. D. Searle & Co. Biarylalkylimidazole derivatives as anti-depressants
IL95760A0 (en) * 1989-09-27 1992-05-25 Rhone Poulenc Sante Imidazole derivatives,their preparation and pharmaceutical compositions containing the same
FR2698789B1 (fr) * 1992-12-07 1995-03-03 Pf Medicament Utilisation de l'idazoxan et ses dérivés pour la préparation d'un médicament destiné au traitement de la maladie de Parkinson et de son évolution.
FR2700113B1 (fr) * 1993-01-07 1995-03-24 Pf Medicament Utilisation de l'Idazoxan et ses dérivés pour la fabrication de médicaments destinés au traitement des maladies neurodégénératives et en particulier l'évolution de la maladie d'Alzheimer.
US6162455A (en) * 1997-01-22 2000-12-19 American Cyanamid Company Method for increasing lean meat, improving the lean meat to fat ratio and improving amino acid utilization in warm-blooded animals
FR2766824B1 (fr) * 1997-07-30 1999-09-10 Adir Nouveaux composes heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2795727B1 (fr) * 1999-06-29 2001-09-21 Pf Medicament Nouveaux derives benzodioxanne imidazolines fluores, leur preparation et leurs applications en therapeutique

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2979511A (en) * 1959-03-25 1961-04-11 Olin Mathieson Certain 1, 4-benzodioxanyl imidazolines and corresponding pyrimidines and process
PH16249A (en) * 1980-02-04 1983-08-16 Reckitt & Colmann Prod Ltd Imidazoline derivatives,its pharmaceutical composition and method of use
NZ199469A (en) * 1981-01-30 1984-03-16 Reckitt & Colmann Prod Ltd Benzodioxanyl-2-imidazoline derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
PL241515A1 (en) 1984-07-30
PT76558B (en) 1986-01-21
IL68318A0 (en) 1983-07-31
HU190894B (en) 1986-12-28
SU1217257A3 (ru) 1986-03-07
GR78528B (en, 2012) 1984-09-27
NO831318L (no) 1983-10-18
NO158019B (no) 1988-03-21
CA1190932A (en) 1985-07-23
AU1329883A (en) 1983-10-20
ZA832278B (en) 1983-12-28
ES8405394A1 (es) 1984-06-01
NO158019C (no) 1988-06-29
FI73676C (fi) 1987-11-09
AU552397B2 (en) 1986-05-29
ES521440A0 (es) 1984-06-01
DE3371631D1 (de) 1987-06-25
EP0092328B1 (en) 1987-05-20
ATE27275T1 (de) 1987-06-15
FI73676B (fi) 1987-07-31
IE830858L (en) 1983-10-17
IL68318A (en) 1986-07-31
DD209628A5 (de) 1984-05-16
GB2118548B (en) 1985-07-31
PL143658B1 (en) 1988-03-31
IE54922B1 (en) 1990-03-28
CS233746B2 (en) 1985-03-14
GB2118548A (en) 1983-11-02
DK160093C (da) 1991-06-24
NZ203680A (en) 1985-08-16
US4446148A (en) 1984-05-01
EP0092328A3 (en) 1985-05-08
DK163783A (da) 1983-10-18
PT76558A (en) 1983-05-01
FI831199A0 (fi) 1983-04-11
JPS58192882A (ja) 1983-11-10
DK160093B (da) 1991-01-28
ZW8783A1 (en) 1983-07-06
FI831199L (fi) 1983-10-18
DK163783D0 (da) 1983-04-14
EP0092328A2 (en) 1983-10-26

Similar Documents

Publication Publication Date Title
RU2095360C1 (ru) Производные индола, их оптические изомеры и фармацевтически приемлемые соли
RU2121998C1 (ru) Производные пиримидина, способ их получения, фармкомпозиция
JP2001521926A (ja) 治療上活性の化合物におけるカテコールのインダゾール生物学的等価物置換
JPH08501559A (ja) セロトニン受容体剤
FR2567885A1 (fr) Derives 3-aminopropoxyaryliques, leur preparation, leur application comme medicaments et compositions pharmaceutiques les contenant
JP2008531609A (ja) 置換されたピリジン誘導体
CA1156241A (en) Imidazoline derivative
JPH08504409A (ja) アミノメチルインダン、‐ベンゾフラン及び‐ベンゾチオフエン
BRPI0619126A2 (pt) derivados espirocìclicos, composição farmacêutica e usos dos mesmos
JPH0233038B2 (en, 2012)
KR20080043314A (ko) 피리미딘 유도체 및 ｋｃｎｑ 포타슘 채널 개방제로서의그의 용도
WO1999027965A1 (en) Antihyperlipemic agents
EP0047531B1 (en) 2-(1,4-benzodioxan-2-ylalkyl) imidazoles, their preparation and pharmaceutical compositions containing them
JPH0427984B2 (en, 2012)
EA008907B1 (ru) Производные индола
HU190983B (en) Process for preparing imidazole derivatives and pharmaceutical compositions containing such compounds
JPH08501285A (ja) Ｎ−シクロアルキルピペラジン誘導体、それらを取得する方法およびそれらを含有する薬学的組成物
DE69021490T2 (de) Phenoxyheterozyklische Verbindungen.
SK10222001A3 (sk) Morfolinobenzamidové soli
EP1192152A1 (fr) Nouveaux derives benzodioxanne imidazolines fluores, leur preparation et leurs applications en therapeutique
JP2003519229A (ja) 新規ヘテロアリール誘導体、その製造方法及びその使用方法
JPH10501263A (ja) 平滑筋弛緩薬としてのシクロブタ−３−エン−１，２−ジオン誘導体
NO153572B (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive 5-(2-(2,3-dihydro-1,4-benzodioxan-2-ylmethyl)-amino)-1-hydroxyethyl)-2-hydroxybenzoesyre-derivater.
JPH02240A (ja) 化合物
HU204256B (en) Process for producing quinoline-2,5-dions and pharmaceutical compositions containing them