PT76558B - Process for the preparation of imidazoline derivatives - Google Patents
Process for the preparation of imidazoline derivativesInfo
- Publication number
- PT76558B PT76558B PT76558A PT7655883A PT76558B PT 76558 B PT76558 B PT 76558B PT 76558 A PT76558 A PT 76558A PT 7655883 A PT7655883 A PT 7655883A PT 76558 B PT76558 B PT 76558B
- Authority
- PT
- Portugal
- Prior art keywords
- sub
- preparation
- imidazoline derivatives
- sup
- formulahaving
- Prior art date
Links
- 150000002462 imidazolines Chemical class 0.000 title abstract 2
- 229940083254 peripheral vasodilators imidazoline derivative Drugs 0.000 title abstract 2
- 125000000094 2-phenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
- 229940082496 Adrenoreceptor antagonist Drugs 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000003518 presynaptic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/12—1,4-Dioxanes; Hydrogenated 1,4-dioxanes not condensed with other rings
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Lock And Its Accessories (AREA)
- Vehicle Interior And Exterior Ornaments, Soundproofing, And Insulation (AREA)
- Photoreceptors In Electrophotography (AREA)
- Paper (AREA)
- Inks, Pencil-Leads, Or Crayons (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8211205 | 1982-04-17 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT76558A PT76558A (en) | 1983-05-01 |
| PT76558B true PT76558B (en) | 1986-01-21 |
Family
ID=10529762
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT76558A PT76558B (en) | 1982-04-17 | 1983-04-15 | Process for the preparation of imidazoline derivatives |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US4446148A (en, 2012) |
| EP (1) | EP0092328B1 (en, 2012) |
| JP (1) | JPS58192882A (en, 2012) |
| AT (1) | ATE27275T1 (en, 2012) |
| AU (1) | AU552397B2 (en, 2012) |
| CA (1) | CA1190932A (en, 2012) |
| CS (1) | CS233746B2 (en, 2012) |
| DD (1) | DD209628A5 (en, 2012) |
| DE (1) | DE3371631D1 (en, 2012) |
| DK (1) | DK160093C (en, 2012) |
| ES (1) | ES521440A0 (en, 2012) |
| FI (1) | FI73676C (en, 2012) |
| GB (1) | GB2118548B (en, 2012) |
| GR (1) | GR78528B (en, 2012) |
| HU (1) | HU190894B (en, 2012) |
| IE (1) | IE54922B1 (en, 2012) |
| IL (1) | IL68318A (en, 2012) |
| NO (1) | NO158019C (en, 2012) |
| NZ (1) | NZ203680A (en, 2012) |
| PL (1) | PL143658B1 (en, 2012) |
| PT (1) | PT76558B (en, 2012) |
| SU (1) | SU1217257A3 (en, 2012) |
| ZA (1) | ZA832278B (en, 2012) |
| ZW (1) | ZW8783A1 (en, 2012) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4882343A (en) * | 1987-08-28 | 1989-11-21 | G. D. Searle & Co. | Biarylalkylimidazole derivatives as anti-depressants |
| IL95760A0 (en) * | 1989-09-27 | 1992-05-25 | Rhone Poulenc Sante | Imidazole derivatives,their preparation and pharmaceutical compositions containing the same |
| FR2698789B1 (fr) * | 1992-12-07 | 1995-03-03 | Pf Medicament | Utilisation de l'idazoxan et ses dérivés pour la préparation d'un médicament destiné au traitement de la maladie de Parkinson et de son évolution. |
| FR2700113B1 (fr) * | 1993-01-07 | 1995-03-24 | Pf Medicament | Utilisation de l'Idazoxan et ses dérivés pour la fabrication de médicaments destinés au traitement des maladies neurodégénératives et en particulier l'évolution de la maladie d'Alzheimer. |
| US6162455A (en) * | 1997-01-22 | 2000-12-19 | American Cyanamid Company | Method for increasing lean meat, improving the lean meat to fat ratio and improving amino acid utilization in warm-blooded animals |
| FR2766824B1 (fr) * | 1997-07-30 | 1999-09-10 | Adir | Nouveaux composes heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2795727B1 (fr) * | 1999-06-29 | 2001-09-21 | Pf Medicament | Nouveaux derives benzodioxanne imidazolines fluores, leur preparation et leurs applications en therapeutique |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2979511A (en) * | 1959-03-25 | 1961-04-11 | Olin Mathieson | Certain 1, 4-benzodioxanyl imidazolines and corresponding pyrimidines and process |
| PH16249A (en) * | 1980-02-04 | 1983-08-16 | Reckitt & Colmann Prod Ltd | Imidazoline derivatives,its pharmaceutical composition and method of use |
| NZ199469A (en) * | 1981-01-30 | 1984-03-16 | Reckitt & Colmann Prod Ltd | Benzodioxanyl-2-imidazoline derivatives and pharmaceutical compositions |
-
1983
- 1983-03-24 NZ NZ203680A patent/NZ203680A/en unknown
- 1983-03-29 US US06/480,370 patent/US4446148A/en not_active Expired - Lifetime
- 1983-03-29 EP EP83301776A patent/EP0092328B1/en not_active Expired
- 1983-03-29 DE DE8383301776T patent/DE3371631D1/de not_active Expired
- 1983-03-29 CS CS832172A patent/CS233746B2/cs unknown
- 1983-03-29 AT AT83301776T patent/ATE27275T1/de active
- 1983-03-30 ZA ZA832278A patent/ZA832278B/xx unknown
- 1983-03-30 GB GB08308885A patent/GB2118548B/en not_active Expired
- 1983-03-31 CA CA000425114A patent/CA1190932A/en not_active Expired
- 1983-04-07 IL IL68318A patent/IL68318A/xx not_active IP Right Cessation
- 1983-04-11 FI FI831199A patent/FI73676C/fi not_active IP Right Cessation
- 1983-04-11 AU AU13298/83A patent/AU552397B2/en not_active Ceased
- 1983-04-12 SU SU833576788A patent/SU1217257A3/ru active
- 1983-04-13 ZW ZW87/83A patent/ZW8783A1/xx unknown
- 1983-04-14 DK DK163783A patent/DK160093C/da not_active IP Right Cessation
- 1983-04-14 GR GR71079A patent/GR78528B/el unknown
- 1983-04-14 NO NO831318A patent/NO158019C/no unknown
- 1983-04-14 ES ES521440A patent/ES521440A0/es active Granted
- 1983-04-15 DD DD83249904A patent/DD209628A5/de not_active IP Right Cessation
- 1983-04-15 IE IE858/83A patent/IE54922B1/en not_active IP Right Cessation
- 1983-04-15 PL PL1983241515A patent/PL143658B1/pl unknown
- 1983-04-15 HU HU831330A patent/HU190894B/hu not_active IP Right Cessation
- 1983-04-15 PT PT76558A patent/PT76558B/pt not_active IP Right Cessation
- 1983-04-15 JP JP58066854A patent/JPS58192882A/ja active Granted
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC3A | Transfer or assignment |
Free format text: 930817 PIERRE FABRE MEDICAMENT, SA. FR |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20000731 |