ES8502076A1 - Procedimiento para la preparacion de acido 3b-(3-carboxipropioniloxi)-ursa-9(11),12-dien-28-oico - Google Patents

Procedimiento para la preparacion de acido 3b-(3-carboxipropioniloxi)-ursa-9(11),12-dien-28-oico

Info

Publication number
ES8502076A1
ES8502076A1 ES524408A ES524408A ES8502076A1 ES 8502076 A1 ES8502076 A1 ES 8502076A1 ES 524408 A ES524408 A ES 524408A ES 524408 A ES524408 A ES 524408A ES 8502076 A1 ES8502076 A1 ES 8502076A1
Authority
ES
Spain
Prior art keywords
carboxypropionyloxy
ursa
beta
salts
dience
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES524408A
Other languages
English (en)
Other versions
ES524408A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ISF SpA
Original Assignee
ISF SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ISF SpA filed Critical ISF SpA
Publication of ES524408A0 publication Critical patent/ES524408A0/es
Publication of ES8502076A1 publication Critical patent/ES8502076A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DEL ACIDO 3BBB-(3-CARBOXIPROPIONILOXI)-URSA-9(11),12-DIEN-28-OICO Y SUS SALES ATOXICAS ACEPTABLES EN FARMACIA.CONSISTE EN SUCCINILAR EL ACIDO 3BBB-HIDROXI-URSA-9(11),12-DIEN-28-OICO, HACIENDOLO REACCIONAR CON ACIDO SUCCINICO O CON UN DERIVADO SUYO REACTIVO. EL HEMISUCCINATO ASI OBTENIDO SE PUEDE CONVERTIR EN UNA SAL ATOXICA APROPIADA, ACEPTABLE EN FARMACIA.DE APLICACION EN MEDICINA POR SU ACTIVIDAD ANTIULCEROSA Y ANTIVIRAL.
ES524408A 1982-07-26 1983-07-23 Procedimiento para la preparacion de acido 3b-(3-carboxipropioniloxi)-ursa-9(11),12-dien-28-oico Expired ES8502076A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8222566A IT1215626B (it) 1982-07-26 1982-07-26 Derivato dell'acido ursolico farmacologicamente attivo.

Publications (2)

Publication Number Publication Date
ES524408A0 ES524408A0 (es) 1984-12-16
ES8502076A1 true ES8502076A1 (es) 1984-12-16

Family

ID=11197905

Family Applications (1)

Application Number Title Priority Date Filing Date
ES524408A Expired ES8502076A1 (es) 1982-07-26 1983-07-23 Procedimiento para la preparacion de acido 3b-(3-carboxipropioniloxi)-ursa-9(11),12-dien-28-oico

Country Status (11)

Country Link
US (1) US4530934A (es)
EP (1) EP0100516B1 (es)
JP (1) JPS5933243A (es)
AT (1) ATE30231T1 (es)
AU (1) AU552998B2 (es)
CA (1) CA1208625A (es)
DE (1) DE3374059D1 (es)
DK (1) DK339783A (es)
ES (1) ES8502076A1 (es)
IT (1) IT1215626B (es)
PT (1) PT77083B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6183007U (es) * 1984-11-06 1986-06-02
JPH07583B2 (ja) * 1990-11-21 1995-01-11 北海道糖業株式会社 水溶性五環性トリテルペン包接化合物及びその製造方法並びにそれを利用した食品、飲料、口腔用組成物
GB9110929D0 (en) * 1991-05-21 1991-07-10 Idb Holding Spa Ursane derivatives,their preparation and pharmaceutical formulations thereof
US6982284B1 (en) 1999-09-10 2006-01-03 Applied Genetics Incorporated Dermatics Compositions and methods for modification of skin lipid content
AU2001283038A1 (en) * 2000-07-31 2002-02-13 University Of Virginia Patent Foundation Inhibitors of dna polymerase sigma
US20040029906A1 (en) * 2001-07-31 2004-02-12 Michael Christman Inhibitors of dna polymerase sigma
CN102241723B (zh) * 2010-05-11 2015-06-03 上海开拓者医药发展有限公司 一种熊果酸盐及其制备方法和晶体
WO2014027777A2 (ko) 2012-08-14 2014-02-20 한국콜마 주식회사 신규한 우르솔릭산 유도체 및 이의 제조 방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1076684B (de) * 1957-07-16 1960-03-03 Biorex Laboratories Ltd Verfahren zur Herstellung von pharmakologisch wirksamen Verbindungen der Glycyrrhetinsaeure
GB1138247A (en) * 1966-08-26 1968-12-27 Biorex Laboratories Ltd Oleanolic acid derivatives
IT1051001B (it) * 1971-08-06 1981-04-21 Isf Spa Processo per la preparazione dell acido 3 o beta carbossipropionil ibbeta glicirretico
GB1414047A (en) * 1973-03-15 1975-11-12 Biorex Laboratories Ltd Ursolic acid derivatives
GB1435622A (en) * 1973-11-07 1976-05-12 Biorex Laboratories Ltd Erythrodiol derivatives
GB1475075A (en) * 1974-09-11 1977-06-01 Biorex Laboratories Ltd Derivatives of glycyrrhetinic and oleanolic acids
GB1476053A (en) * 1975-02-07 1977-06-10 Biorex Laboratories Ltd Glycyrrhetinic acid derivatives
JPS588044A (ja) * 1981-07-06 1983-01-18 Maruzen Seiyaku Kk １１−デオキソグリチルレチン酸水素マレ−ト及びそれを有効成分とする医薬

Also Published As

Publication number Publication date
CA1208625A (en) 1986-07-29
IT1215626B (it) 1990-02-22
ES524408A0 (es) 1984-12-16
EP0100516A3 (en) 1985-11-06
EP0100516A2 (de) 1984-02-15
JPS5933243A (ja) 1984-02-23
JPH0373533B2 (es) 1991-11-22
DK339783A (da) 1984-01-27
ATE30231T1 (de) 1987-10-15
EP0100516B1 (de) 1987-10-14
DK339783D0 (da) 1983-07-25
AU1726183A (en) 1984-02-02
AU552998B2 (en) 1986-06-26
PT77083B (en) 1986-04-11
IT8222566A0 (it) 1982-07-26
DE3374059D1 (en) 1987-11-19
US4530934A (en) 1985-07-23
PT77083A (en) 1983-08-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19960603