JPH0244449B2 - - Google Patents
Info
- Publication number
- JPH0244449B2 JPH0244449B2 JP59010980A JP1098084A JPH0244449B2 JP H0244449 B2 JPH0244449 B2 JP H0244449B2 JP 59010980 A JP59010980 A JP 59010980A JP 1098084 A JP1098084 A JP 1098084A JP H0244449 B2 JPH0244449 B2 JP H0244449B2
- Authority
- JP
- Japan
- Prior art keywords
- cholesterol
- tea
- formula
- group
- catechins
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 claims description 22
- 235000012000 cholesterol Nutrition 0.000 claims description 8
- WMBWREPUVVBILR-UHFFFAOYSA-N GCG Natural products C=1C(O)=C(O)C(O)=CC=1C1OC2=CC(O)=CC(O)=C2CC1OC(=O)C1=CC(O)=C(O)C(O)=C1 WMBWREPUVVBILR-UHFFFAOYSA-N 0.000 claims description 7
- 229930014124 (-)-epigallocatechin gallate Natural products 0.000 claims description 3
- 235000004911 (-)-epigallocatechin gallate Nutrition 0.000 claims description 3
- VFSWRBJYBQXUTE-UHFFFAOYSA-N epi-Gallocatechin 3-O-gallate Natural products Oc1ccc2C(=O)C(OC(=O)c3cc(O)c(O)c(O)c3)C(Oc2c1)c4cc(O)c(O)c(O)c4 VFSWRBJYBQXUTE-UHFFFAOYSA-N 0.000 claims description 3
- 239000003112 inhibitor Substances 0.000 claims description 3
- 239000004480 active ingredient Substances 0.000 claims description 2
- 244000269722 Thea sinensis Species 0.000 description 12
- 235000013616 tea Nutrition 0.000 description 12
- ADRVNXBAWSRFAJ-UHFFFAOYSA-N catechin Natural products OC1Cc2cc(O)cc(O)c2OC1c3ccc(O)c(O)c3 ADRVNXBAWSRFAJ-UHFFFAOYSA-N 0.000 description 11
- 235000005487 catechin Nutrition 0.000 description 11
- 150000001765 catechin Chemical class 0.000 description 9
- XMOCLSLCDHWDHP-IUODEOHRSA-N epi-Gallocatechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@H]2O)=CC(O)=C(O)C(O)=C1 XMOCLSLCDHWDHP-IUODEOHRSA-N 0.000 description 6
- 239000008280 blood Substances 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 5
- 210000004185 liver Anatomy 0.000 description 5
- XMOCLSLCDHWDHP-UHFFFAOYSA-N L-Epigallocatechin Natural products OC1CC2=C(O)C=C(O)C=C2OC1C1=CC(O)=C(O)C(O)=C1 XMOCLSLCDHWDHP-UHFFFAOYSA-N 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- PFTAWBLQPZVEMU-DZGCQCFKSA-N (+)-3',4',5,7-Tetrahydroxy-2,3-trans-flavan-3-ol Natural products C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-DZGCQCFKSA-N 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 3
- 150000002632 lipids Chemical class 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 241000700159 Rattus Species 0.000 description 2
- 229950001002 cianidanol Drugs 0.000 description 2
- 238000006911 enzymatic reaction Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 229910001220 stainless steel Inorganic materials 0.000 description 2
- 239000010935 stainless steel Substances 0.000 description 2
- 229930013783 (-)-epicatechin Natural products 0.000 description 1
- 235000007355 (-)-epicatechin Nutrition 0.000 description 1
- PFTAWBLQPZVEMU-UKRRQHHQSA-N (-)-epicatechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-UKRRQHHQSA-N 0.000 description 1
- LSHVYAFMTMFKBA-TZIWHRDSSA-N (-)-epicatechin-3-O-gallate Chemical compound O([C@@H]1CC2=C(O)C=C(C=C2O[C@@H]1C=1C=C(O)C(O)=CC=1)O)C(=O)C1=CC(O)=C(O)C(O)=C1 LSHVYAFMTMFKBA-TZIWHRDSSA-N 0.000 description 1
- 241000251468 Actinopterygii Species 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 208000014644 Brain disease Diseases 0.000 description 1
- LSHVYAFMTMFKBA-UHFFFAOYSA-N ECG Natural products C=1C=C(O)C(O)=CC=1C1OC2=CC(O)=CC(O)=C2CC1OC(=O)C1=CC(O)=C(O)C(O)=C1 LSHVYAFMTMFKBA-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 102000001554 Hemoglobins Human genes 0.000 description 1
- 108010054147 Hemoglobins Proteins 0.000 description 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
- 238000008214 LDL Cholesterol Methods 0.000 description 1
- 108010028554 LDL Cholesterol Proteins 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 235000006468 Thea sinensis Nutrition 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 230000003385 bacteriostatic effect Effects 0.000 description 1
- 235000020279 black tea Nutrition 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 239000005018 casein Substances 0.000 description 1
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 description 1
- 235000021240 caseins Nutrition 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 230000001877 deodorizing effect Effects 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000005562 fading Methods 0.000 description 1
- 239000003925 fat Substances 0.000 description 1
- 235000021050 feed intake Nutrition 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 235000009569 green tea Nutrition 0.000 description 1
- 208000019622 heart disease Diseases 0.000 description 1
- 238000005534 hematocrit Methods 0.000 description 1
- 229960002897 heparin Drugs 0.000 description 1
- 229920000669 heparin Polymers 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 235000008935 nutritious Nutrition 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 230000001766 physiological effect Effects 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000000384 rearing effect Effects 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 229920001864 tannin Polymers 0.000 description 1
- 239000001648 tannin Substances 0.000 description 1
- 235000018553 tannin Nutrition 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
- Pyrane Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP59010980A JPS60156614A (ja) | 1984-01-26 | 1984-01-26 | コレステロ−ル上昇抑制剤 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP59010980A JPS60156614A (ja) | 1984-01-26 | 1984-01-26 | コレステロ−ル上昇抑制剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS60156614A JPS60156614A (ja) | 1985-08-16 |
| JPH0244449B2 true JPH0244449B2 (de) | 1990-10-04 |
Family
ID=11765302
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP59010980A Granted JPS60156614A (ja) | 1984-01-26 | 1984-01-26 | コレステロ−ル上昇抑制剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS60156614A (de) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04352726A (ja) * | 1990-08-17 | 1992-12-07 | Nikko Kyodo Co Ltd | 動脈硬化防止剤及び動脈硬化防止作用を有する機能性食品 |
| JPH0626341U (ja) * | 1992-07-08 | 1994-04-08 | 村田機械株式会社 | ハンドセットホルダ |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63214183A (ja) * | 1987-03-03 | 1988-09-06 | Mitsui Norin Kk | アンジオテンシン１変換酵素阻害剤 |
| JP2011105763A (ja) * | 2000-06-21 | 2011-06-02 | Kao Corp | Ｐｐａｒ依存的遺伝子転写活性化剤 |
| ES2236331T3 (es) | 2000-11-17 | 2005-07-16 | Kao Corporation | Bebidas envasadas. |
| JP3403400B1 (ja) | 2001-09-28 | 2003-05-06 | 花王株式会社 | 容器詰飲料 |
| JP3378577B1 (ja) | 2001-09-28 | 2003-02-17 | 花王株式会社 | 飲 料 |
| EP2382877B8 (de) | 2002-10-28 | 2013-10-30 | Kao Corporation | Grüntee-Extrakt |
| JP2006104213A (ja) * | 2003-02-10 | 2006-04-20 | Ito En Ltd | 血清コレステロールを低下させるために用いる飲食物およびその製造方法 |
| CN100518528C (zh) | 2003-09-26 | 2009-07-29 | 花王株式会社 | 容器装饮料 |
| JP3597857B2 (ja) | 2003-10-31 | 2004-12-08 | 花王株式会社 | 容器詰茶飲料 |
| EP1690457B1 (de) | 2003-12-02 | 2010-08-11 | Kao Corporation | Verpacktes getränk |
| JP3766670B2 (ja) | 2003-12-16 | 2006-04-12 | 花王株式会社 | 容器詰飲料 |
| ES2367889T3 (es) | 2003-12-18 | 2011-11-10 | Kao Corporation | Bebida embotellada. |
| JP4247166B2 (ja) | 2004-08-06 | 2009-04-02 | 花王株式会社 | 非重合体カテキン類含有茶抽出物の製造法 |
| WO2006022314A1 (ja) * | 2004-08-25 | 2006-03-02 | Asahi Breweries, Ltd. | コレステロール代謝制御剤、それを含有する飲食品、食品添加物及び医薬 |
| JP3742096B1 (ja) * | 2005-02-08 | 2006-02-01 | 花王株式会社 | 非茶系容器詰飲料 |
| JP3742094B1 (ja) * | 2004-11-04 | 2006-02-01 | 花王株式会社 | 非茶系容器詰飲料 |
| WO2007020917A1 (ja) * | 2005-08-18 | 2007-02-22 | The University Of Tokushima | ユートロフィン産生の増強持続剤とこれを用いる加工食品 |
| KR101334438B1 (ko) | 2005-09-01 | 2013-11-29 | 카오카부시키가이샤 | 녹차 추출물의 제조법 |
| KR20070026005A (ko) * | 2005-09-01 | 2007-03-08 | 카오카부시키가이샤 | 정제 녹차 추출물의 제조 방법 |
| JP4884003B2 (ja) | 2005-12-27 | 2012-02-22 | 花王株式会社 | 容器詰烏龍茶飲料 |
| JP4562682B2 (ja) | 2006-04-17 | 2010-10-13 | 花王株式会社 | 精製緑茶抽出物の製造法 |
| JP4569965B2 (ja) | 2006-04-17 | 2010-10-27 | 花王株式会社 | 精製緑茶抽出物の製造法 |
| JP5080835B2 (ja) | 2006-07-04 | 2012-11-21 | 花王株式会社 | 発泡性容器詰飲料 |
| US8962678B2 (en) | 2006-07-05 | 2015-02-24 | Kao Corporation | Senescence inhibitor |
| CN101484157B (zh) | 2006-07-05 | 2012-02-29 | 花王株式会社 | 肌肉力量提高剂 |
| JP2008088146A (ja) | 2006-09-08 | 2008-04-17 | Kao Corp | インスリン感受性改善剤 |
| EP2098121B1 (de) | 2006-12-22 | 2013-09-18 | Kao Corporation | Containerverpacktes grünteegetränk |
| CN101541185B (zh) | 2006-12-28 | 2013-06-12 | 花王株式会社 | 茶提取物 |
| DE602008005424D1 (de) | 2007-01-24 | 2011-04-21 | Kao Corp | Katechine enthaltende konditorwaren |
| JP2008200032A (ja) | 2007-01-24 | 2008-09-04 | Kao Corp | パン類 |
| WO2008139725A1 (ja) | 2007-05-08 | 2008-11-20 | Kao Corporation | 還元飲料用濃縮組成物 |
| KR101475758B1 (ko) | 2007-08-08 | 2014-12-23 | 가오 가부시키가이샤 | 차 추출물의 제조방법 |
| JP5294758B2 (ja) | 2007-08-30 | 2013-09-18 | 花王株式会社 | インスタント粉末飲料 |
| JP6353034B2 (ja) * | 2014-04-23 | 2018-07-04 | 日本製紙株式会社 | 糖尿病予防または改善剤 |
| WO2018117002A1 (ja) | 2016-12-21 | 2018-06-28 | サントリーホールディングス株式会社 | エピガロカテキンガレート及びシクロプロリルトレオニンを含有する飲食品 |
| JP7171954B2 (ja) | 2021-03-22 | 2022-11-15 | 花王株式会社 | カテキン類含有組成物 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2711927A1 (de) * | 1976-03-23 | 1977-10-06 | Inverni Della Beffa Spa | Pharmazeutisch wirksame polyphenole und verfahren zu ihrer herstellung |
| JPS55145611A (en) * | 1979-05-02 | 1980-11-13 | Do Rushierushie Ind Soc | Therapeutically useful drug for treating disease of atheroma or vessel system* made of 3**methoxyflavilium derivative |
| JPS57118580A (en) * | 1981-01-16 | 1982-07-23 | Kanebo Ltd | Novel catechin derivative |
-
1984
- 1984-01-26 JP JP59010980A patent/JPS60156614A/ja active Granted
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2711927A1 (de) * | 1976-03-23 | 1977-10-06 | Inverni Della Beffa Spa | Pharmazeutisch wirksame polyphenole und verfahren zu ihrer herstellung |
| JPS55145611A (en) * | 1979-05-02 | 1980-11-13 | Do Rushierushie Ind Soc | Therapeutically useful drug for treating disease of atheroma or vessel system* made of 3**methoxyflavilium derivative |
| JPS57118580A (en) * | 1981-01-16 | 1982-07-23 | Kanebo Ltd | Novel catechin derivative |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04352726A (ja) * | 1990-08-17 | 1992-12-07 | Nikko Kyodo Co Ltd | 動脈硬化防止剤及び動脈硬化防止作用を有する機能性食品 |
| JPH0626341U (ja) * | 1992-07-08 | 1994-04-08 | 村田機械株式会社 | ハンドセットホルダ |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS60156614A (ja) | 1985-08-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EXPY | Cancellation because of completion of term |