JPH0142938B2 - - Google Patents

Info

Publication number
JPH0142938B2
JPH0142938B2 JP59119000A JP11900084A JPH0142938B2 JP H0142938 B2 JPH0142938 B2 JP H0142938B2 JP 59119000 A JP59119000 A JP 59119000A JP 11900084 A JP11900084 A JP 11900084A JP H0142938 B2 JPH0142938 B2 JP H0142938B2
Authority
JP
Japan
Prior art keywords
sub
group
sup
general formula
carbon atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP59119000A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6149A (ja
Inventor
Haniroku Myake
Tadao Okegawa
Akyoshi Kawasaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ono Pharmaceutical Co Ltd
Original Assignee
Ono Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co Ltd filed Critical Ono Pharmaceutical Co Ltd
Priority to JP59119000A priority Critical patent/JPS6149A/ja
Priority to ZA854237A priority patent/ZA854237B/xx
Priority to CA000483112A priority patent/CA1261826A/en
Priority to GR851412A priority patent/GR851412B/el
Priority to NO852319A priority patent/NO852319L/no
Priority to US06/743,548 priority patent/US4792550A/en
Priority to HU852294A priority patent/HU196740B/hu
Priority to DK260085A priority patent/DK260085A/da
Priority to ES544054A priority patent/ES8705370A1/es
Priority to FI852319A priority patent/FI852319A7/fi
Priority to PT80626A priority patent/PT80626B/pt
Priority to KR1019850004120A priority patent/KR860000256A/ko
Priority to DE8585304148T priority patent/DE3565255D1/de
Priority to AT85304148T priority patent/ATE37535T1/de
Priority to EP85304148A priority patent/EP0171146B1/en
Priority to AU43495/85A priority patent/AU575653B2/en
Priority to YU00999/85A priority patent/YU99985A/xx
Publication of JPS6149A publication Critical patent/JPS6149A/ja
Priority to ES552192A priority patent/ES8704880A1/es
Priority to YU84087A priority patent/YU46201B/sh
Publication of JPH0142938B2 publication Critical patent/JPH0142938B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/05—Alcohols containing rings other than six-membered aromatic rings
    • C07C33/14—Alcohols containing rings other than six-membered aromatic rings containing six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
    • C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
    • C07C405/0091—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is bridged condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
    • C07C59/11—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups containing rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Slide Fasteners, Snap Fasteners, And Hook Fasteners (AREA)
  • Indole Compounds (AREA)
  • Coupling Device And Connection With Printed Circuit (AREA)
  • Interconnected Communication Systems, Intercoms, And Interphones (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Prostheses (AREA)
JP59119000A 1984-06-12 1984-06-12 新規な１３―アザ―１４―オキソ―ＴｘＡ２類似化合物およびそれらを有効成分として含有するトロンボキサン起因疾患治療剤 Granted JPS6149A (ja)

Priority Applications (19)

Application Number Priority Date Filing Date Title
JP59119000A JPS6149A (ja) 1984-06-12 1984-06-12 新規な１３―アザ―１４―オキソ―ＴｘＡ２類似化合物およびそれらを有効成分として含有するトロンボキサン起因疾患治療剤
ZA854237A ZA854237B (en) 1984-06-12 1985-06-04 13-aza-14-oxo-txa2 analogues
CA000483112A CA1261826A (en) 1984-06-12 1985-06-04 13-aza-14-oxo-txa.sub.2 analogues
GR851412A GR851412B (en, 2012) 1984-06-12 1985-06-10
NO852319A NO852319L (no) 1984-06-12 1985-06-10 Fremgangsmaate for fremstilling av 13-aza-14-okso-txa2-analog-forbindelser.
FI852319A FI852319A7 (fi) 1984-06-12 1985-06-11 13-atsa-14-okso-tromboksaani A2-analogeja.
HU852294A HU196740B (en) 1984-06-12 1985-06-11 Process for producing 13-aza-14-oxo-txa under 2 analogues and pharmaceutical compositions comprising such active ingredient
DK260085A DK260085A (da) 1984-06-12 1985-06-11 13-aza-14-oxo-txa2-analoger
ES544054A ES8705370A1 (es) 1984-06-12 1985-06-11 Un procedimiento para la preparacion de nuevos derivados del acido 3-axa-14-oxo-carbatron-52 enoico.
US06/743,548 US4792550A (en) 1984-06-12 1985-06-11 13-aza-14-oxo-TXA2 analogues
PT80626A PT80626B (pt) 1984-06-12 1985-06-11 Processo para a preparacao de analogos de 13-aza-14-oxo-txa2 e de composicoes farmaceuticas que os contem.
EP85304148A EP0171146B1 (en) 1984-06-12 1985-06-12 13-aza-14-oxo-txa2 analogues
DE8585304148T DE3565255D1 (en) 1984-06-12 1985-06-12 13-aza-14-oxo-txa2 analogues
AT85304148T ATE37535T1 (de) 1984-06-12 1985-06-12 13-aza-14-oxo-txa2-analoge.
KR1019850004120A KR860000256A (ko) 1984-06-12 1985-06-12 13-아자-14-옥소-txa₂동족체의 제조방법
AU43495/85A AU575653B2 (en) 1984-06-12 1985-06-12 13-aza-14-oxo-txa2 analogues
YU00999/85A YU99985A (en) 1984-06-12 1985-06-13 Process for preparing new derivatives 13-aza-14-oxo-txa2
ES552192A ES8704880A1 (es) 1984-06-12 1986-02-19 Un procedimiento para la preparacion de nuevos analogos de 13-aza-14-oxo-txa2
YU84087A YU46201B (sh) 1984-06-12 1987-05-11 Postopek za pripravo novih analogov 13-aza-14-okso-txa2

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59119000A JPS6149A (ja) 1984-06-12 1984-06-12 新規な１３―アザ―１４―オキソ―ＴｘＡ２類似化合物およびそれらを有効成分として含有するトロンボキサン起因疾患治療剤

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP28877688A Division JPH01151545A (ja) 1988-11-17 1988-11-17 新規な１３−アザ−１４−オキソーｔｘａ↓２類似化合物

Publications (2)

Publication Number Publication Date
JPS6149A JPS6149A (ja) 1986-01-06
JPH0142938B2 true JPH0142938B2 (en, 2012) 1989-09-18

Family

ID=14750515

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59119000A Granted JPS6149A (ja) 1984-06-12 1984-06-12 新規な１３―アザ―１４―オキソ―ＴｘＡ２類似化合物およびそれらを有効成分として含有するトロンボキサン起因疾患治療剤

Country Status (17)

Country Link
US (1) US4792550A (en, 2012)
EP (1) EP0171146B1 (en, 2012)
JP (1) JPS6149A (en, 2012)
KR (1) KR860000256A (en, 2012)
AT (1) ATE37535T1 (en, 2012)
AU (1) AU575653B2 (en, 2012)
CA (1) CA1261826A (en, 2012)
DE (1) DE3565255D1 (en, 2012)
DK (1) DK260085A (en, 2012)
ES (2) ES8705370A1 (en, 2012)
FI (1) FI852319A7 (en, 2012)
GR (1) GR851412B (en, 2012)
HU (1) HU196740B (en, 2012)
NO (1) NO852319L (en, 2012)
PT (1) PT80626B (en, 2012)
YU (2) YU99985A (en, 2012)
ZA (1) ZA854237B (en, 2012)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6395479U (en, 2012) * 1986-12-09 1988-06-20
JPH0226306Y2 (en, 2012) * 1986-12-31 1990-07-18
JPH02234630A (ja) * 1989-03-07 1990-09-17 Hideo Hayakawa 有害動物の威嚇装置
JPH039183U (en, 2012) * 1989-06-08 1991-01-29
JP3195361B2 (ja) 1995-06-21 2001-08-06 塩野義製薬株式会社 ビシクロ環系アミノ誘導体およびそれを含有するｐｇｄ２拮抗剤
US6069166A (en) * 1996-12-12 2000-05-30 Shionogi & Co., Ltd. Fused heterocyclic benzenecarboxamide derivatives and PGD2 antagonists comprising them
BR9714016A (pt) * 1996-12-13 2000-02-29 Shionogi & Co Derivados de benzotiofenocarboxamida e antagonistas a pgd2, que compreendem os mesmos
US6225336B1 (en) 1997-09-19 2001-05-01 Shionogi & Co., Ltd. Compounds having [2.2.1] bicyclo skeleton
US6506789B2 (en) 1998-06-03 2003-01-14 Shionogi & Co., Ltd. Methods for the treatment of itching comprising administering PGD2 receptor antagonist

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3162659D1 (en) * 1980-07-22 1984-04-19 Ono Pharmaceutical Co 9,11-methano-13-aza-11a-carbathrombanoic acid analogues and pharmaceutical use thereof
GB2113678B (en) * 1981-12-23 1985-06-19 Nat Res Dev Prostaglandins

Also Published As

Publication number Publication date
HUT37914A (en) 1986-03-28
YU46201B (sh) 1993-05-28
EP0171146B1 (en) 1988-09-28
ES552192A0 (es) 1987-04-16
CA1261826A (en) 1989-09-26
YU84087A (en) 1987-12-31
HU196740B (en) 1989-01-30
PT80626A (en) 1985-07-01
DK260085D0 (da) 1985-06-11
FI852319L (fi) 1985-12-13
JPS6149A (ja) 1986-01-06
ES8704880A1 (es) 1987-04-16
DK260085A (da) 1985-12-13
AU575653B2 (en) 1988-08-04
PT80626B (pt) 1994-11-30
EP0171146A1 (en) 1986-02-12
YU99985A (en) 1987-12-31
ES544054A0 (es) 1987-05-01
ZA854237B (en) 1986-03-26
DE3565255D1 (en) 1988-11-03
FI852319A0 (fi) 1985-06-11
NO852319L (no) 1985-12-13
US4792550A (en) 1988-12-20
ATE37535T1 (de) 1988-10-15
KR860000256A (ko) 1986-01-27
GR851412B (en, 2012) 1985-11-25
ES8705370A1 (es) 1987-05-01
AU4349585A (en) 1985-12-19
FI852319A7 (fi) 1985-12-13

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