HU196740B - Process for producing 13-aza-14-oxo-txa under 2 analogues and pharmaceutical compositions comprising such active ingredient - Google Patents
Process for producing 13-aza-14-oxo-txa under 2 analogues and pharmaceutical compositions comprising such active ingredient Download PDFInfo
- Publication number
- HU196740B HU196740B HU852294A HU229485A HU196740B HU 196740 B HU196740 B HU 196740B HU 852294 A HU852294 A HU 852294A HU 229485 A HU229485 A HU 229485A HU 196740 B HU196740 B HU 196740B
- Authority
- HU
- Hungary
- Prior art keywords
- oxo
- aza
- enoic acid
- pharmaceutically acceptable
- acceptable salt
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/05—Alcohols containing rings other than six-membered aromatic rings
- C07C33/14—Alcohols containing rings other than six-membered aromatic rings containing six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
- C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
- C07C405/0091—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is bridged condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
- C07C59/11—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups containing rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Slide Fasteners, Snap Fasteners, And Hook Fasteners (AREA)
- Indole Compounds (AREA)
- Coupling Device And Connection With Printed Circuit (AREA)
- Interconnected Communication Systems, Intercoms, And Interphones (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Prostheses (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP59119000A JPS6149A (ja) | 1984-06-12 | 1984-06-12 | 新規な１３―アザ―１４―オキソ―ＴｘＡ２類似化合物およびそれらを有効成分として含有するトロンボキサン起因疾患治療剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUT37914A HUT37914A (en) | 1986-03-28 |
| HU196740B true HU196740B (en) | 1989-01-30 |
Family
ID=14750515
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU852294A HU196740B (en) | 1984-06-12 | 1985-06-11 | Process for producing 13-aza-14-oxo-txa under 2 analogues and pharmaceutical compositions comprising such active ingredient |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4792550A (en, 2012) |
| EP (1) | EP0171146B1 (en, 2012) |
| JP (1) | JPS6149A (en, 2012) |
| KR (1) | KR860000256A (en, 2012) |
| AT (1) | ATE37535T1 (en, 2012) |
| AU (1) | AU575653B2 (en, 2012) |
| CA (1) | CA1261826A (en, 2012) |
| DE (1) | DE3565255D1 (en, 2012) |
| DK (1) | DK260085A (en, 2012) |
| ES (2) | ES8705370A1 (en, 2012) |
| FI (1) | FI852319A7 (en, 2012) |
| GR (1) | GR851412B (en, 2012) |
| HU (1) | HU196740B (en, 2012) |
| NO (1) | NO852319L (en, 2012) |
| PT (1) | PT80626B (en, 2012) |
| YU (2) | YU99985A (en, 2012) |
| ZA (1) | ZA854237B (en, 2012) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6395479U (en, 2012) * | 1986-12-09 | 1988-06-20 | ||
| JPH0226306Y2 (en, 2012) * | 1986-12-31 | 1990-07-18 | ||
| JPH02234630A (ja) * | 1989-03-07 | 1990-09-17 | Hideo Hayakawa | 有害動物の威嚇装置 |
| JPH039183U (en, 2012) * | 1989-06-08 | 1991-01-29 | ||
| JP3195361B2 (ja) | 1995-06-21 | 2001-08-06 | 塩野義製薬株式会社 | ビシクロ環系アミノ誘導体およびそれを含有するｐｇｄ２拮抗剤 |
| US6069166A (en) * | 1996-12-12 | 2000-05-30 | Shionogi & Co., Ltd. | Fused heterocyclic benzenecarboxamide derivatives and PGD2 antagonists comprising them |
| BR9714016A (pt) * | 1996-12-13 | 2000-02-29 | Shionogi & Co | Derivados de benzotiofenocarboxamida e antagonistas a pgd2, que compreendem os mesmos |
| US6225336B1 (en) | 1997-09-19 | 2001-05-01 | Shionogi & Co., Ltd. | Compounds having [2.2.1] bicyclo skeleton |
| US6506789B2 (en) | 1998-06-03 | 2003-01-14 | Shionogi & Co., Ltd. | Methods for the treatment of itching comprising administering PGD2 receptor antagonist |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3162659D1 (en) * | 1980-07-22 | 1984-04-19 | Ono Pharmaceutical Co | 9,11-methano-13-aza-11a-carbathrombanoic acid analogues and pharmaceutical use thereof |
| GB2113678B (en) * | 1981-12-23 | 1985-06-19 | Nat Res Dev | Prostaglandins |
-
1984
- 1984-06-12 JP JP59119000A patent/JPS6149A/ja active Granted
-
1985
- 1985-06-04 CA CA000483112A patent/CA1261826A/en not_active Expired
- 1985-06-04 ZA ZA854237A patent/ZA854237B/xx unknown
- 1985-06-10 GR GR851412A patent/GR851412B/el unknown
- 1985-06-10 NO NO852319A patent/NO852319L/no unknown
- 1985-06-11 US US06/743,548 patent/US4792550A/en not_active Expired - Fee Related
- 1985-06-11 HU HU852294A patent/HU196740B/hu not_active IP Right Cessation
- 1985-06-11 FI FI852319A patent/FI852319A7/fi not_active Application Discontinuation
- 1985-06-11 ES ES544054A patent/ES8705370A1/es not_active Expired
- 1985-06-11 DK DK260085A patent/DK260085A/da not_active Application Discontinuation
- 1985-06-11 PT PT80626A patent/PT80626B/pt not_active IP Right Cessation
- 1985-06-12 KR KR1019850004120A patent/KR860000256A/ko not_active Withdrawn
- 1985-06-12 AT AT85304148T patent/ATE37535T1/de not_active IP Right Cessation
- 1985-06-12 EP EP85304148A patent/EP0171146B1/en not_active Expired
- 1985-06-12 DE DE8585304148T patent/DE3565255D1/de not_active Expired
- 1985-06-12 AU AU43495/85A patent/AU575653B2/en not_active Ceased
- 1985-06-13 YU YU00999/85A patent/YU99985A/xx unknown
-
1986
- 1986-02-19 ES ES552192A patent/ES8704880A1/es not_active Expired
-
1987
- 1987-05-11 YU YU84087A patent/YU46201B/sh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUT37914A (en) | 1986-03-28 |
| YU46201B (sh) | 1993-05-28 |
| EP0171146B1 (en) | 1988-09-28 |
| ES552192A0 (es) | 1987-04-16 |
| CA1261826A (en) | 1989-09-26 |
| YU84087A (en) | 1987-12-31 |
| PT80626A (en) | 1985-07-01 |
| DK260085D0 (da) | 1985-06-11 |
| FI852319L (fi) | 1985-12-13 |
| JPH0142938B2 (en, 2012) | 1989-09-18 |
| JPS6149A (ja) | 1986-01-06 |
| ES8704880A1 (es) | 1987-04-16 |
| DK260085A (da) | 1985-12-13 |
| AU575653B2 (en) | 1988-08-04 |
| PT80626B (pt) | 1994-11-30 |
| EP0171146A1 (en) | 1986-02-12 |
| YU99985A (en) | 1987-12-31 |
| ES544054A0 (es) | 1987-05-01 |
| ZA854237B (en) | 1986-03-26 |
| DE3565255D1 (en) | 1988-11-03 |
| FI852319A0 (fi) | 1985-06-11 |
| NO852319L (no) | 1985-12-13 |
| US4792550A (en) | 1988-12-20 |
| ATE37535T1 (de) | 1988-10-15 |
| KR860000256A (ko) | 1986-01-27 |
| GR851412B (en, 2012) | 1985-11-25 |
| ES8705370A1 (es) | 1987-05-01 |
| AU4349585A (en) | 1985-12-19 |
| FI852319A7 (fi) | 1985-12-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HU90 | Patent valid on 900628 | ||
| HMM4 | Cancellation of final prot. due to non-payment of fee |