GR851412B - - Google Patents
Info
- Publication number
- GR851412B GR851412B GR851412A GR850101412A GR851412B GR 851412 B GR851412 B GR 851412B GR 851412 A GR851412 A GR 851412A GR 850101412 A GR850101412 A GR 850101412A GR 851412 B GR851412 B GR 851412B
- Authority
- GR
- Greece
- Prior art keywords
- sub
- group
- sup
- substituted
- straight
- Prior art date
Links
- 125000004432 carbon atom Chemical group C* 0.000 abstract 8
- 229910052799 carbon Inorganic materials 0.000 abstract 7
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 125000005843 halogen group Chemical group 0.000 abstract 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- 125000003277 amino group Chemical group 0.000 abstract 2
- 125000000000 cycloalkoxy group Chemical group 0.000 abstract 2
- 125000005366 cycloalkylthio group Chemical group 0.000 abstract 2
- 125000003356 phenylsulfanyl group Chemical group [*]SC1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 2
- 206010002383 Angina Pectoris Diseases 0.000 abstract 1
- 206010008190 Cerebrovascular accident Diseases 0.000 abstract 1
- 229920000858 Cyclodextrin Polymers 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 206010061216 Infarction Diseases 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 208000006011 Stroke Diseases 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 230000001154 acute effect Effects 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 230000003042 antagnostic effect Effects 0.000 abstract 1
- 210000001367 artery Anatomy 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 210000001772 blood platelet Anatomy 0.000 abstract 1
- 230000000747 cardiac effect Effects 0.000 abstract 1
- 230000002490 cerebral effect Effects 0.000 abstract 1
- 206010008118 cerebral infarction Diseases 0.000 abstract 1
- 208000026106 cerebrovascular disease Diseases 0.000 abstract 1
- 230000008602 contraction Effects 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 208000019622 heart disease Diseases 0.000 abstract 1
- 125000003392 indanyl group Chemical group C1(CCC2=CC=CC=C12)* 0.000 abstract 1
- 125000001041 indolyl group Chemical group 0.000 abstract 1
- 230000007574 infarction Effects 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- -1 phenyloxy, phenylthio Chemical group 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 abstract 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- RZWIIPASKMUIAC-VQTJNVASSA-N thromboxane Chemical compound CCCCCCCC[C@H]1OCCC[C@@H]1CCCCCCC RZWIIPASKMUIAC-VQTJNVASSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/05—Alcohols containing rings other than six-membered aromatic rings
- C07C33/14—Alcohols containing rings other than six-membered aromatic rings containing six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
- C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
- C07C405/0091—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is bridged condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
- C07C59/11—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups containing rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Slide Fasteners, Snap Fasteners, And Hook Fasteners (AREA)
- Indole Compounds (AREA)
- Interconnected Communication Systems, Intercoms, And Interphones (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Coupling Device And Connection With Printed Circuit (AREA)
- Prostheses (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP59119000A JPS6149A (ja) | 1984-06-12 | 1984-06-12 | 新規な１３―アザ―１４―オキソ―ＴｘＡ２類似化合物およびそれらを有効成分として含有するトロンボキサン起因疾患治療剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR851412B true GR851412B (el) | 1985-11-25 |
Family
ID=14750515
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR851412A GR851412B (el) | 1984-06-12 | 1985-06-10 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4792550A (el) |
| EP (1) | EP0171146B1 (el) |
| JP (1) | JPS6149A (el) |
| KR (1) | KR860000256A (el) |
| AT (1) | ATE37535T1 (el) |
| AU (1) | AU575653B2 (el) |
| CA (1) | CA1261826A (el) |
| DE (1) | DE3565255D1 (el) |
| DK (1) | DK260085A (el) |
| ES (2) | ES8705370A1 (el) |
| FI (1) | FI852319L (el) |
| GR (1) | GR851412B (el) |
| HU (1) | HU196740B (el) |
| NO (1) | NO852319L (el) |
| PT (1) | PT80626B (el) |
| YU (2) | YU99985A (el) |
| ZA (1) | ZA854237B (el) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6395479U (el) * | 1986-12-09 | 1988-06-20 | ||
| JPH0226306Y2 (el) * | 1986-12-31 | 1990-07-18 | ||
| JPH02234630A (ja) * | 1989-03-07 | 1990-09-17 | Hideo Hayakawa | 有害動物の威嚇装置 |
| JPH039183U (el) * | 1989-06-08 | 1991-01-29 | ||
| CA2225250C (en) | 1995-06-21 | 2005-03-22 | Shionogi & Co., Ltd. | Bicyclic amino derivatives and pgd2 antagonist containing the same |
| ATE295360T1 (de) * | 1996-12-12 | 2005-05-15 | Shionogi & Co | Kondensierte heterocyclische benzolcarbonsäureamid-derivate und diese enthaltende pgd2 antagonisten |
| CZ297324B6 (cs) * | 1996-12-13 | 2006-11-15 | Shionogi & Co., Ltd. | Benzothiofenkarboxamidové deriváty a antagonisty PGD2, které je obsahují |
| WO1999015502A1 (fr) | 1997-09-19 | 1999-04-01 | Shionogi & Co., Ltd. | Composes ayant un squelette [2.2.1]bicyclo |
| US6506789B2 (en) | 1998-06-03 | 2003-01-14 | Shionogi & Co., Ltd. | Methods for the treatment of itching comprising administering PGD2 receptor antagonist |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3162659D1 (en) * | 1980-07-22 | 1984-04-19 | Ono Pharmaceutical Co | 9,11-methano-13-aza-11a-carbathrombanoic acid analogues and pharmaceutical use thereof |
| AU561739B2 (en) * | 1981-12-23 | 1987-05-14 | British Technology Group Limited | Prostaglandins |
-
1984
- 1984-06-12 JP JP59119000A patent/JPS6149A/ja active Granted
-
1985
- 1985-06-04 CA CA000483112A patent/CA1261826A/en not_active Expired
- 1985-06-04 ZA ZA854237A patent/ZA854237B/xx unknown
- 1985-06-10 GR GR851412A patent/GR851412B/el unknown
- 1985-06-10 NO NO852319A patent/NO852319L/no unknown
- 1985-06-11 DK DK260085A patent/DK260085A/da not_active Application Discontinuation
- 1985-06-11 HU HU852294A patent/HU196740B/hu not_active IP Right Cessation
- 1985-06-11 US US06/743,548 patent/US4792550A/en not_active Expired - Fee Related
- 1985-06-11 FI FI852319A patent/FI852319L/fi not_active Application Discontinuation
- 1985-06-11 ES ES544054A patent/ES8705370A1/es not_active Expired
- 1985-06-11 PT PT80626A patent/PT80626B/pt not_active IP Right Cessation
- 1985-06-12 AU AU43495/85A patent/AU575653B2/en not_active Ceased
- 1985-06-12 KR KR1019850004120A patent/KR860000256A/ko not_active Application Discontinuation
- 1985-06-12 EP EP85304148A patent/EP0171146B1/en not_active Expired
- 1985-06-12 DE DE8585304148T patent/DE3565255D1/de not_active Expired
- 1985-06-12 AT AT85304148T patent/ATE37535T1/de not_active IP Right Cessation
- 1985-06-13 YU YU00999/85A patent/YU99985A/xx unknown
-
1986
- 1986-02-19 ES ES552192A patent/ES8704880A1/es not_active Expired
-
1987
- 1987-05-11 YU YU84087A patent/YU46201B/sh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6149A (ja) | 1986-01-06 |
| EP0171146A1 (en) | 1986-02-12 |
| YU99985A (en) | 1987-12-31 |
| ES552192A0 (es) | 1987-04-16 |
| PT80626B (pt) | 1994-11-30 |
| KR860000256A (ko) | 1986-01-27 |
| ATE37535T1 (de) | 1988-10-15 |
| DE3565255D1 (en) | 1988-11-03 |
| US4792550A (en) | 1988-12-20 |
| JPH0142938B2 (el) | 1989-09-18 |
| AU4349585A (en) | 1985-12-19 |
| ZA854237B (en) | 1986-03-26 |
| ES8705370A1 (es) | 1987-05-01 |
| EP0171146B1 (en) | 1988-09-28 |
| PT80626A (en) | 1985-07-01 |
| YU46201B (sh) | 1993-05-28 |
| ES544054A0 (es) | 1987-05-01 |
| AU575653B2 (en) | 1988-08-04 |
| YU84087A (en) | 1987-12-31 |
| FI852319A0 (fi) | 1985-06-11 |
| CA1261826A (en) | 1989-09-26 |
| NO852319L (no) | 1985-12-13 |
| HU196740B (en) | 1989-01-30 |
| HUT37914A (en) | 1986-03-28 |
| ES8704880A1 (es) | 1987-04-16 |
| DK260085A (da) | 1985-12-13 |
| DK260085D0 (da) | 1985-06-11 |
| FI852319L (fi) | 1985-12-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3565255D1 (en) | 13-aza-14-oxo-txa2 analogues | |
| ES8504690A1 (es) | Un procedimiento para preparar una n-(4-(3-aminopropil)-aminobutil)-2-(acido w-guanidino-graso-amido)-2-alcoxietanamida | |
| AU3381389A (en) | Derivative of caffeic acid and pharmaceutical composition containing the same | |
| EP0233686A3 (en) | Bis phenyl ethanol amines and bis phenyoxypropanolamines having a beta-agonist activity | |
| ES2029830T3 (es) | Un procedimiento para preparar un derivado de 6-cetoprostaglandina e1. | |
| ES2062078T3 (es) | Derivados 4-aminofenol y procedimientos para la preparacion de los mismos. | |
| DE3889208D1 (de) | Thioformamid-Derivate. | |
| KR900018135A (ko) | 레닌-저해 활성을 가지는 신규의 아미노산 유도체 | |
| GR851995B (el) | ||
| ATE63537T1 (de) | Carbacyclin-derivate. | |
| MY104048A (en) | New allylaminoethylazoles. | |
| EP0375387A3 (en) | Amide compounds | |
| SE8005260L (sv) | Nya isokinolinderivat samt framstellning derav | |
| DK0455899T3 (da) | Prostaglandin I-analog | |
| KR940006987A (ko) | 신규한 히드로퀴논 유도체 | |
| RU92015764A (ru) | 2-гидрокси-5-бромбензоил-/6-фторхроман-3-аль/-гидразон, обладающий коагуляционной активностью | |
| ES2041785T3 (es) | Un procedimiento para preparar nuevos derivados de prostaglandinas. |