JP7695232B2 - ヘテロアリール血漿カリクレインインヒビター - Google Patents

ヘテロアリール血漿カリクレインインヒビター Download PDF

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Publication number
JP7695232B2
JP7695232B2 JP2022517389A JP2022517389A JP7695232B2 JP 7695232 B2 JP7695232 B2 JP 7695232B2 JP 2022517389 A JP2022517389 A JP 2022517389A JP 2022517389 A JP2022517389 A JP 2022517389A JP 7695232 B2 JP7695232 B2 JP 7695232B2
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methyl
pyridin
pharma
nitrogen
compound
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Japanese (ja)
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JP2022549601A (ja
JP2022549601A5 (https=
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ニコラオス パパイオアヌー，
ジェレミー マーク トラビンス，
サラ ジョセリン フィンク，
ジョン マーク エラード，
アラステア レイ，
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Takeda Pharmaceutical Co Ltd
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Takeda Pharmaceutical Co Ltd
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Priority to JP2025094801A priority Critical patent/JP2025124882A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
JP2022517389A 2019-09-18 2020-09-17 ヘテロアリール血漿カリクレインインヒビター Active JP7695232B2 (ja)

Priority Applications (1)

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JP2025094801A JP2025124882A (ja) 2019-09-18 2025-06-06 ヘテロアリール血漿カリクレインインヒビター

Applications Claiming Priority (3)

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US201962902333P 2019-09-18 2019-09-18
US62/902,333 2019-09-18
PCT/US2020/051249 WO2021055589A1 (en) 2019-09-18 2020-09-17 Heteroaryl plasma kallikrein inhibitors

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Publications (3)

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JP2022549601A JP2022549601A (ja) 2022-11-28
JP2022549601A5 JP2022549601A5 (https=) 2023-09-25
JP7695232B2 true JP7695232B2 (ja) 2025-06-18

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JP2022517389A Active JP7695232B2 (ja) 2019-09-18 2020-09-17 ヘテロアリール血漿カリクレインインヒビター
JP2025094801A Pending JP2025124882A (ja) 2019-09-18 2025-06-06 ヘテロアリール血漿カリクレインインヒビター

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US (2) US11370803B2 (https=)
EP (1) EP4031245A1 (https=)
JP (2) JP7695232B2 (https=)
CN (1) CN114667289B (https=)
WO (1) WO2021055589A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019028362A1 (en) 2017-08-04 2019-02-07 Dyax Corp. INHIBITORS OF PLASMATIC KALLIKREIN AND USES THEREOF
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EP4031245A1 (en) 2019-09-18 2022-07-27 Takeda Pharmaceutical Company Limited Heteroaryl plasma kallikrein inhibitors
DK4031547T3 (da) 2019-09-18 2024-09-09 Takeda Pharmaceuticals Co Plasmakallikreininhibitorer og anvendelser deraf

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JP2022548696A (ja) 2019-09-18 2022-11-21 武田薬品工業株式会社 血漿カリクレインインヒビター及びその使用

Also Published As

Publication number Publication date
JP2022549601A (ja) 2022-11-28
CN114667289A (zh) 2022-06-24
JP2025124882A (ja) 2025-08-26
WO2021055589A1 (en) 2021-03-25
US12065448B2 (en) 2024-08-20
US11370803B2 (en) 2022-06-28
US20220298176A1 (en) 2022-09-22
CN114667289B (zh) 2025-08-26
EP4031245A1 (en) 2022-07-27
US20210079022A1 (en) 2021-03-18

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