JP7687767B2 - 呼吸器合胞体ウイルスワクチン - Google Patents

呼吸器合胞体ウイルスワクチン Download PDF

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Publication number
JP7687767B2
JP7687767B2 JP2018541089A JP2018541089A JP7687767B2 JP 7687767 B2 JP7687767 B2 JP 7687767B2 JP 2018541089 A JP2018541089 A JP 2018541089A JP 2018541089 A JP2018541089 A JP 2018541089A JP 7687767 B2 JP7687767 B2 JP 7687767B2
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rsv
vaccine
rna
mrna
methyl
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Japanese (ja)
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JP2019501208A5 (enExample
JP2019501208A (ja
Inventor
ジュゼッペ チャラメッラ，
カピル バール，
エイミー エスペセス，
ダイ ワン，
アンドリュー ジェイ． ベット，
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ModernaTx Inc
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ModernaTx Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=58558153&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP7687767(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
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Publication of JP2019501208A publication Critical patent/JP2019501208A/ja
Publication of JP2019501208A5 publication Critical patent/JP2019501208A5/ja
Priority to JP2022172576A priority Critical patent/JP2023015151A/ja
Priority to JP2024227631A priority patent/JP2025041835A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7115—Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6018—Lipids, e.g. in lipopeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18534—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2018541089A 2015-10-22 2016-10-21 呼吸器合胞体ウイルスワクチン Active JP7687767B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022172576A JP2023015151A (ja) 2015-10-22 2022-10-27 呼吸器合胞体ウイルスワクチン
JP2024227631A JP2025041835A (ja) 2015-10-22 2024-12-24 呼吸器合胞体ウイルスワクチン

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201562245031P 2015-10-22 2015-10-22
US201562245208P 2015-10-22 2015-10-22
US62/245,031 2015-10-22
US62/245,208 2015-10-22
US201562247563P 2015-10-28 2015-10-28
US62/247,563 2015-10-28
US201562248250P 2015-10-29 2015-10-29
US62/248,250 2015-10-29
PCT/US2016/058321 WO2017070622A1 (en) 2015-10-22 2016-10-21 Respiratory syncytial virus vaccine

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2022172576A Division JP2023015151A (ja) 2015-10-22 2022-10-27 呼吸器合胞体ウイルスワクチン
JP2024227631A Division JP2025041835A (ja) 2015-10-22 2024-12-24 呼吸器合胞体ウイルスワクチン

Publications (3)

Publication Number Publication Date
JP2019501208A JP2019501208A (ja) 2019-01-17
JP2019501208A5 JP2019501208A5 (enExample) 2019-12-05
JP7687767B2 true JP7687767B2 (ja) 2025-06-03

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Family Applications (3)

Application Number Title Priority Date Filing Date
JP2018541089A Active JP7687767B2 (ja) 2015-10-22 2016-10-21 呼吸器合胞体ウイルスワクチン
JP2022172576A Pending JP2023015151A (ja) 2015-10-22 2022-10-27 呼吸器合胞体ウイルスワクチン
JP2024227631A Pending JP2025041835A (ja) 2015-10-22 2024-12-24 呼吸器合胞体ウイルスワクチン

Family Applications After (2)

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JP2022172576A Pending JP2023015151A (ja) 2015-10-22 2022-10-27 呼吸器合胞体ウイルスワクチン
JP2024227631A Pending JP2025041835A (ja) 2015-10-22 2024-12-24 呼吸器合胞体ウイルスワクチン

Country Status (20)

Country Link
US (2) US20180271970A1 (enExample)
EP (1) EP3365008A4 (enExample)
JP (3) JP7687767B2 (enExample)
KR (1) KR20180096592A (enExample)
CN (1) CN108472354A (enExample)
AU (1) AU2016341311B2 (enExample)
BR (1) BR112018008102A2 (enExample)
CA (1) CA3002820A1 (enExample)
CL (1) CL2018001053A1 (enExample)
CO (1) CO2018005229A2 (enExample)
EA (1) EA201891000A1 (enExample)
IL (1) IL258831A (enExample)
MA (1) MA46317A (enExample)
MX (1) MX2018004917A (enExample)
PE (1) PE20181530A1 (enExample)
PH (1) PH12018500856A1 (enExample)
SG (2) SG10201914006UA (enExample)
TN (1) TN2018000154A1 (enExample)
TW (1) TW201729836A (enExample)
WO (1) WO2017070622A1 (enExample)

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