JP7447388B2 - 感染性疾患の治療のための共受容体システム - Google Patents

感染性疾患の治療のための共受容体システム Download PDF

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JP7447388B2
JP7447388B2 JP2021500150A JP2021500150A JP7447388B2 JP 7447388 B2 JP7447388 B2 JP 7447388B2 JP 2021500150 A JP2021500150 A JP 2021500150A JP 2021500150 A JP2021500150 A JP 2021500150A JP 7447388 B2 JP7447388 B2 JP 7447388B2
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cells
domain
cell
antigen
ccor
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JP2021524264A (ja
JP2021524264A5 (enExample
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ツェン、ミン
チェン、ル
ウ、シュ
チェン、リリ
リウ、シュン
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Nanjing Legend Biotechnology Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2812—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD4
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
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    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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JP2021500150A 2018-07-13 2019-07-12 感染性疾患の治療のための共受容体システム Active JP7447388B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CNPCT/CN2018/095650 2018-07-13
CN2018095650 2018-07-13
CN2019087259 2019-05-16
CNPCT/CN2019/087259 2019-05-16
PCT/CN2019/095738 WO2020011247A1 (en) 2018-07-13 2019-07-12 Co-receptor systems for treating infectious diseases

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JP2021524264A JP2021524264A (ja) 2021-09-13
JP2021524264A5 JP2021524264A5 (enExample) 2022-07-14
JP7447388B2 true JP7447388B2 (ja) 2024-03-12

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US (1) US20210275589A1 (enExample)
EP (1) EP3820888A4 (enExample)
JP (1) JP7447388B2 (enExample)
KR (1) KR20210031898A (enExample)
CN (1) CN112334479A (enExample)
AU (1) AU2019302603A1 (enExample)
SG (1) SG11202012339WA (enExample)
TW (1) TWI841576B (enExample)
WO (1) WO2020011247A1 (enExample)

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ES2911448T3 (es) 2016-03-09 2022-05-19 American Gene Tech Int Inc Vectores combinados y métodos para el tratamiento del cáncer
CA3028982A1 (en) 2016-07-08 2018-01-11 American Gene Technologies International Inc. Hiv pre-immunization and immunotherapy
US12559769B2 (en) 2017-06-16 2026-02-24 American Gene Technologies International Inc. Methods and compositions for the activation of tumor cytotoxicity via human gamma-delta t-cells
EP3876952A4 (en) 2018-11-05 2022-08-24 American Gene Technologies International Inc. VECTOR SYSTEM FOR EXPRESSING REGULATORY RNA
CN113840912A (zh) * 2019-05-16 2021-12-24 南京传奇生物科技有限公司 包含识别分子的工程化免疫细胞
AU2021232603A1 (en) * 2020-03-03 2022-10-20 American Gene Technologies International Inc. On demand expression of exogenous factors in lymphocytes to treat HIV
WO2021180832A1 (en) 2020-03-12 2021-09-16 Universiteit Gent Hybrid car and hybrid tcr cells to treat infectious diseases
US12497623B2 (en) * 2020-05-04 2025-12-16 The Trustees Of The University Of Pennsylvania Non-signaling HIV fusion inhibitors and methods of use thereof
US20240050474A1 (en) * 2021-02-09 2024-02-15 Nanjing Legend Biotech Co., Ltd. Engineered cells and uses thereof
WO2025011508A1 (zh) * 2023-07-07 2025-01-16 深圳先进技术研究院 降低肿瘤内中性粒细胞水平的抗肿瘤细菌
CN120329439A (zh) * 2024-01-18 2025-07-18 中国人民解放军军事科学院军事医学研究院 一种单克隆抗体及其应用
FR3168604A1 (fr) * 2024-11-18 2026-05-22 Asfalia Biologics Promoteurs inductibles par des molecules pharmacologiques
CN121015699B (zh) * 2025-08-21 2026-04-10 广州淳泰生物医药科技有限公司 一种nkt细胞制剂及其制备方法和应用

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JP2018504894A (ja) 2014-12-19 2018-02-22 デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド キメラ抗原受容体およびその使用方法
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