JP7054924B2 - 免疫療法のためのｆｌｔ３指向ｃａｒ細胞 - Google Patents

免疫療法のためのｆｌｔ３指向ｃａｒ細胞 Download PDF

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JP7054924B2
JP7054924B2 JP2018534523A JP2018534523A JP7054924B2 JP 7054924 B2 JP7054924 B2 JP 7054924B2 JP 2018534523 A JP2018534523 A JP 2018534523A JP 2018534523 A JP2018534523 A JP 2018534523A JP 7054924 B2 JP7054924 B2 JP 7054924B2
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cells
flt3
car
cell
amino acid
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JP2018529380A5 (enExample
JP2018529380A (ja
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ユイ、チエンホア
カリジューリ、マイケル
ディヴァイン、スティーヴン
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Cytoimmune Therapeutics Inc
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JP2018534523A 2015-09-23 2016-09-23 免疫療法のためのｆｌｔ３指向ｃａｒ細胞 Active JP7054924B2 (ja)

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US201562222695P 2015-09-23 2015-09-23
US62/222,695 2015-09-23
PCT/US2016/053577 WO2017053889A2 (en) 2015-09-23 2016-09-23 Flt3 directed car cells for immunotherapy

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US (2) US10961312B2 (enExample)
EP (2) EP3352784A4 (enExample)
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KR (1) KR20180053744A (enExample)
CN (1) CN109310744A (enExample)
AU (2) AU2016326721C1 (enExample)
CA (1) CA2999037A1 (enExample)
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JP7054924B2 (ja) * 2015-09-23 2022-04-15 サイトイミューン セラピューティクス， インコーポレイテッド 免疫療法のためのｆｌｔ３指向ｃａｒ細胞
AU2017271606B2 (en) 2016-05-27 2024-08-01 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services FLT3-specific chimeric antigen receptors and methods using same
WO2018119279A1 (en) * 2016-12-21 2018-06-28 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Human monoclonal antibodies specific for flt3 and uses thereof
CA3053539A1 (en) 2017-02-27 2018-08-30 Juno Therapeutics, Inc. Compositions, articles of manufacture and methods related to dosing in cell therapy
MY201327A (en) * 2017-06-02 2024-02-16 Pfizer Chimeric antigen receptors targeting flt3
EP3630841A1 (en) * 2017-06-02 2020-04-08 Pfizer Inc. Antibodies specific for flt3 and their uses
CN111542323A (zh) * 2017-08-01 2020-08-14 尤利乌斯·马克西米利安维尔茨堡大学 Flt3 car-t细胞和flt3抑制剂在治疗急性髓细胞性白血病中的用途
EP3662055A1 (en) * 2017-08-02 2020-06-10 Autolus Limited Cells expressing a chimeric antigen receptor or engineered tcr and comprising a nucleotide sequence which is selectively expressed
WO2019089855A1 (en) 2017-11-01 2019-05-09 Juno Therapeutics, Inc. Process for generating therapeutic compositions of engineered cells
CN118530373A (zh) * 2017-11-10 2024-08-23 朱拉生物公司 基于主要组织相容性复合物的嵌合受体和其用于治疗自身免疫性疾病的用途
CN109988759A (zh) * 2017-12-29 2019-07-09 上海细胞治疗研究院 一种在t细胞中具有高转录活性的嵌合启动子
US20190328785A1 (en) * 2018-04-30 2019-10-31 The Board Of Regents Of The University Of Oklahoma Flt3-binding chimeric antigen receptors, cells, and uses thereof
CN110305847B (zh) * 2018-07-27 2021-05-18 赛诺生（深圳）基因产业发展有限公司 一种用于治疗肿瘤的基因工程细胞
CN109134665B (zh) * 2018-08-24 2021-06-11 上海先博生物科技有限公司 一种基于单域抗体的bcma嵌合抗原受体及应用
WO2020113194A2 (en) * 2018-11-30 2020-06-04 Juno Therapeutics, Inc. Methods for treatment using adoptive cell therapy
EP3902836A4 (en) 2018-12-18 2022-08-31 Boehringer Ingelheim IO Canada Inc. FLT3 AGONISTIC ANTIBODIES AND THEIR USES
SG11202111130SA (en) 2019-04-30 2021-11-29 Senti Biosciences Inc Chimeric receptors and methods of use thereof
WO2021054789A1 (ko) * 2019-09-18 2021-03-25 주식회사 에스엘바이젠 신규 키메라 항원 수용체 암호화 유전자가 형질도입된 유전자 변형 nk 세포주 및 그의 용도
KR102287180B1 (ko) 2019-10-01 2021-08-09 충북대학교 산학협력단 Cd138에 특이적으로 결합하는 키메릭 항원 수용체, 이를 발현하는 면역세포 및 이의 항암 용도
US20230113183A1 (en) * 2020-04-09 2023-04-13 Autolus Limited Cell
WO2021212069A1 (en) * 2020-04-17 2021-10-21 City Of Hope Flt3-targeted chimeric antigen receptor modified cells for treatment of flt3-positive malignancies
CN111647071B (zh) * 2020-06-17 2023-05-05 深圳豪石生物科技有限公司 识别靶细胞表面抗原的t细胞受体及其组合物
CN116410315A (zh) * 2021-12-31 2023-07-11 博生吉医药科技(苏州)有限公司 一种新型靶向人flt3的嵌合抗原受体修饰的t细胞的构建及应用

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JP2013515472A (ja) 2009-12-23 2013-05-09 シュニムネ ゲーエムベーハー 抗ｆｌｔ３抗体及びその使用方法
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