JP7025414B2 - Ｔｒｐｖ４拮抗薬 - Google Patents

Ｔｒｐｖ４拮抗薬 Download PDF

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JP7025414B2
JP7025414B2 JP2019515462A JP2019515462A JP7025414B2 JP 7025414 B2 JP7025414 B2 JP 7025414B2 JP 2019515462 A JP2019515462 A JP 2019515462A JP 2019515462 A JP2019515462 A JP 2019515462A JP 7025414 B2 JP7025414 B2 JP 7025414B2
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Japan
Prior art keywords
sulfonyl
hydroxy
pyrrolidine
hydroxymethyl
oxy
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JP2019515462A
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Japanese (ja)
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JP2019529443A (ja
JP2019529443A5 (OSRAM
Inventor
エドワード、ジェイ．ブルナルディク
カール、エイ．ブルックス
ブライアン、グリフィン、ロウホーン
イェ、グゥオセン
リンダ、エス．バートン
ブライアン、ダブリュ．ブドゥジック
ジェイ、エム．マシューズ
ジョン、ジェフリー、マカティー
ジャクリン、アール．パターソン
ジョセフ、イー．ペロ
ロバート、サンチェス
マシュー、ロバート、センダー
ラモント、ロスコー、テレル
デイビッド、ジェイ．ベーム
ジェームズ、ブイ．トーマス
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GlaxoSmithKline Intellectual Property No 2 Ltd
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GlaxoSmithKline Intellectual Property No 2 Ltd
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
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