JP6943859B2 - 駆虫性デプシペプチド化合物 - Google Patents
駆虫性デプシペプチド化合物 Download PDFInfo
- Publication number
- JP6943859B2 JP6943859B2 JP2018534122A JP2018534122A JP6943859B2 JP 6943859 B2 JP6943859 B2 JP 6943859B2 JP 2018534122 A JP2018534122 A JP 2018534122A JP 2018534122 A JP2018534122 A JP 2018534122A JP 6943859 B2 JP6943859 B2 JP 6943859B2
- Authority
- JP
- Japan
- Prior art keywords
- independently
- alkyl
- substituted
- alkoxy
- halogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- NNQYLWZZECRXLT-OAHLLOKOSA-N O[C@H](Cc(cc1)ccc1Br)C(OCc1ccccc1)=O Chemical compound O[C@H](Cc(cc1)ccc1Br)C(OCc1ccccc1)=O NNQYLWZZECRXLT-OAHLLOKOSA-N 0.000 description 2
- NKJIYYDCYKUWNB-UHFFFAOYSA-N Brc(cc1)cnc1N1CCOCC1 Chemical compound Brc(cc1)cnc1N1CCOCC1 NKJIYYDCYKUWNB-UHFFFAOYSA-N 0.000 description 1
- 0 C*[C@@](CC(C)C)C(O[C@](C)C(OCc1ccccc1)=O)=O Chemical compound C*[C@@](CC(C)C)C(O[C@](C)C(OCc1ccccc1)=O)=O 0.000 description 1
- YNAVUWVOSKDBBP-UHFFFAOYSA-N C1NCCOC1 Chemical compound C1NCCOC1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 description 1
- YDLHWKNKFAPLAJ-QMMMGPOBSA-N CC(C)(C)OC(N(C)[C@@H](CC(C)(C)F)C(O)=O)=O Chemical compound CC(C)(C)OC(N(C)[C@@H](CC(C)(C)F)C(O)=O)=O YDLHWKNKFAPLAJ-QMMMGPOBSA-N 0.000 description 1
- AXASDQQMFBCTSO-VQTJNVASSA-N CC(C)(C)OC(N(C)[C@@H](CC(C)(C)F)C(O[C@H](Cc(cc1)ccc1N1CCOCC1)C(O)=O)=O)=O Chemical compound CC(C)(C)OC(N(C)[C@@H](CC(C)(C)F)C(O[C@H](Cc(cc1)ccc1N1CCOCC1)C(O)=O)=O)=O AXASDQQMFBCTSO-VQTJNVASSA-N 0.000 description 1
- DSXAVEWTGBOPRC-RRPNLBNLSA-N CC(C)(C)OC(N(C)[C@@H](CC(C)(C)F)C(O[C@H](Cc(cc1)ccc1N1CCOCC1)C(OCc1ccccc1)=O)=O)=O Chemical compound CC(C)(C)OC(N(C)[C@@H](CC(C)(C)F)C(O[C@H](Cc(cc1)ccc1N1CCOCC1)C(OCc1ccccc1)=O)=O)=O DSXAVEWTGBOPRC-RRPNLBNLSA-N 0.000 description 1
- UGLPCXPIGBLEJV-YEOOOGFDSA-N CC(C)(C)OC(N(C)[C@@H](CC(C)([O]1[C@H](Cc(cc2)cc(F)c2C2=CCOCC2)C(OCc2ccccc2)=O)F)C1=O)=O Chemical compound CC(C)(C)OC(N(C)[C@@H](CC(C)([O]1[C@H](Cc(cc2)cc(F)c2C2=CCOCC2)C(OCc2ccccc2)=O)F)C1=O)=O UGLPCXPIGBLEJV-YEOOOGFDSA-N 0.000 description 1
- YLAGHBFGSYSQND-VIFPVBQESA-N CC(C)(C)OC(N(C)[C@@H](CC1CC1)C(O)=O)=O Chemical compound CC(C)(C)OC(N(C)[C@@H](CC1CC1)C(O)=O)=O YLAGHBFGSYSQND-VIFPVBQESA-N 0.000 description 1
- UZKQORCTKMSVSF-LEWJYISDSA-N CC(C)(C)OC(N(C)[C@@H](CC1CC1)C(O[C@H](Cc(cc1)ccc1N1CCOCC1)C(O)=O)=O)=O Chemical compound CC(C)(C)OC(N(C)[C@@H](CC1CC1)C(O[C@H](Cc(cc1)ccc1N1CCOCC1)C(O)=O)=O)=O UZKQORCTKMSVSF-LEWJYISDSA-N 0.000 description 1
- FZLQFOZNGDFTIP-WUFINQPMSA-N CC(C)(C)OC(N(C)[C@@H](CC1CC1)C(O[C@H](Cc(cc1)ccc1N1CCOCC1)C(OCc1ccccc1)=O)=O)=O Chemical compound CC(C)(C)OC(N(C)[C@@H](CC1CC1)C(O[C@H](Cc(cc1)ccc1N1CCOCC1)C(OCc1ccccc1)=O)=O)=O FZLQFOZNGDFTIP-WUFINQPMSA-N 0.000 description 1
- GKRRTFCDSZGFSZ-QMMMGPOBSA-N CC(C)(C)OC(N[C@@H](CC1CC1)C(O)=O)=O Chemical compound CC(C)(C)OC(N[C@@H](CC1CC1)C(O)=O)=O GKRRTFCDSZGFSZ-QMMMGPOBSA-N 0.000 description 1
- ICFGYUOQRWVQLG-AEFFLSMTSA-N CC(C)C[C@@H](C(O[C@H](C)C(OCc1ccccc1)=O)=O)N(C)C(OC(C)(C)C)=O Chemical compound CC(C)C[C@@H](C(O[C@H](C)C(OCc1ccccc1)=O)=O)N(C)C(OC(C)(C)C)=O ICFGYUOQRWVQLG-AEFFLSMTSA-N 0.000 description 1
- FXIJZOQWQFFENP-HIFRSBDPSA-N CC(C)C[C@@H](C(O[C@H](C)C(OCc1ccccc1)=O)=O)NC Chemical compound CC(C)C[C@@H](C(O[C@H](C)C(OCc1ccccc1)=O)=O)NC FXIJZOQWQFFENP-HIFRSBDPSA-N 0.000 description 1
- NLPREOAVJYMBKZ-CDMHEIPLSA-N CCC(C(C)F)[C@@H](C(O[C@H](Cc(cc1)ccc1N1CCOCC1)C(O)=O)=O)N(C)C(OC(C)(C)C)=O Chemical compound CCC(C(C)F)[C@@H](C(O[C@H](Cc(cc1)ccc1N1CCOCC1)C(O)=O)=O)N(C)C(OC(C)(C)C)=O NLPREOAVJYMBKZ-CDMHEIPLSA-N 0.000 description 1
- KYNLNERYAWYHOI-GXDHUFHOSA-N COC(/C(/O)=C\c(cc1)ccc1C1=CCOCC1)=O Chemical compound COC(/C(/O)=C\c(cc1)ccc1C1=CCOCC1)=O KYNLNERYAWYHOI-GXDHUFHOSA-N 0.000 description 1
- BYWCHBPJXQVZNN-UKOABYEESA-N C[C@H](C(N(C)[C@@H](CC(C)(C)F)C(O[C@H](Cc(cc1)ccc1C1=CCOCC1)C(OCc1ccccc1)=O)=O)=O)OC(C1(CC1)N(C)C(OC(C)(C)C)=O)=O Chemical compound C[C@H](C(N(C)[C@@H](CC(C)(C)F)C(O[C@H](Cc(cc1)ccc1C1=CCOCC1)C(OCc1ccccc1)=O)=O)=O)OC(C1(CC1)N(C)C(OC(C)(C)C)=O)=O BYWCHBPJXQVZNN-UKOABYEESA-N 0.000 description 1
- KLVWTTRCDRCFRQ-SWSTZQHCSA-N C[C@H](C(N(C)[C@@H](CC(C)(C)F)C(O[C@H](Cc1ccc(C2CCOCC2)cc1)C(N(C)[C@@H](CC1CC1)C(O[C@H](C)C(O)=O)=O)=O)=O)=O)OC([C@H](CC1CC1)N(C)C([C@@H](Cc1ccc(C2CCOCC2)cc1)OC([C@H](CC(C)(C)F)NC)=O)=O)=O Chemical compound C[C@H](C(N(C)[C@@H](CC(C)(C)F)C(O[C@H](Cc1ccc(C2CCOCC2)cc1)C(N(C)[C@@H](CC1CC1)C(O[C@H](C)C(O)=O)=O)=O)=O)=O)OC([C@H](CC1CC1)N(C)C([C@@H](Cc1ccc(C2CCOCC2)cc1)OC([C@H](CC(C)(C)F)NC)=O)=O)=O KLVWTTRCDRCFRQ-SWSTZQHCSA-N 0.000 description 1
- OOABBKNCZRUFJL-ZHUXWESOSA-N C[C@H](C(N(C)[C@@H](CC(C)(C)F)C(O[C@H](Cc1ccc(C2CCOCC2)cc1)C(N(C)[C@@H](CC1CC1)C(O[C@H](C)C(OCc1ccccc1)=O)=O)=O)=O)=O)OC([C@H](CC1CC1)N(C)C([C@@H](Cc1ccc(C2CCOCC2)cc1)OC([C@H](CC(C)(C)F)NC)=O)=O)=O Chemical compound C[C@H](C(N(C)[C@@H](CC(C)(C)F)C(O[C@H](Cc1ccc(C2CCOCC2)cc1)C(N(C)[C@@H](CC1CC1)C(O[C@H](C)C(OCc1ccccc1)=O)=O)=O)=O)=O)OC([C@H](CC1CC1)N(C)C([C@@H](Cc1ccc(C2CCOCC2)cc1)OC([C@H](CC(C)(C)F)NC)=O)=O)=O OOABBKNCZRUFJL-ZHUXWESOSA-N 0.000 description 1
- SUVITXLJQHJCCC-QGUKFAFCSA-N C[C@H](C(N(C)[C@@H](CC(C)(C)F)C(O[C@H](Cc1ccc(C2CCOCC2)cc1)C(O)=O)=O)=O)OC(C1(CC1)N(C)C(OC(C)(C)C)=O)=O Chemical compound C[C@H](C(N(C)[C@@H](CC(C)(C)F)C(O[C@H](Cc1ccc(C2CCOCC2)cc1)C(O)=O)=O)=O)OC(C1(CC1)N(C)C(OC(C)(C)C)=O)=O SUVITXLJQHJCCC-QGUKFAFCSA-N 0.000 description 1
- CFOGRAVBUPWOJP-MRVPVSSYSA-N C[C@H](C(O)=O)OC(C1(CC1)N(C)C(OC(C)(C)C)=O)=O Chemical compound C[C@H](C(O)=O)OC(C1(CC1)N(C)C(OC(C)(C)C)=O)=O CFOGRAVBUPWOJP-MRVPVSSYSA-N 0.000 description 1
- GRKWVQLSYHAEQL-CQSZACIVSA-N C[C@H](C(OCc1ccccc1)=O)OC(C1(CC1)N(C)C(OC(C)(C)C)=O)=O Chemical compound C[C@H](C(OCc1ccccc1)=O)OC(C1(CC1)N(C)C(OC(C)(C)C)=O)=O GRKWVQLSYHAEQL-CQSZACIVSA-N 0.000 description 1
- GASSUHXGJJTYPK-JJVQHPENSA-N C[C@H](C(OCc1ccccc1)=O)OC([C@H](CC1CC1)N(C)C([C@@H](Cc(cc1)ccc1N1CCOCC1)OC([C@H](CC(C)(C)F)N(C)C(OC(C)(C)C)=O)=O)=O)=O Chemical compound C[C@H](C(OCc1ccccc1)=O)OC([C@H](CC1CC1)N(C)C([C@@H](Cc(cc1)ccc1N1CCOCC1)OC([C@H](CC(C)(C)F)N(C)C(OC(C)(C)C)=O)=O)=O)=O GASSUHXGJJTYPK-JJVQHPENSA-N 0.000 description 1
- ANEULEDCQHRMBA-DOMZBBRYSA-N C[C@H](C(OCc1ccccc1)=O)OC([C@H](CC1CC1)NC)=O Chemical compound C[C@H](C(OCc1ccccc1)=O)OC([C@H](CC1CC1)NC)=O ANEULEDCQHRMBA-DOMZBBRYSA-N 0.000 description 1
- PEAOEIWYQVXZMB-UHFFFAOYSA-N Clc(cc1)ncc1Br Chemical compound Clc(cc1)ncc1Br PEAOEIWYQVXZMB-UHFFFAOYSA-N 0.000 description 1
- KNQZVZHVJCIMTL-QMMMGPOBSA-N N[C@@H](Cc(cc1)cc(F)c1Br)C(O)=O Chemical compound N[C@@H](Cc(cc1)cc(F)c1Br)C(O)=O KNQZVZHVJCIMTL-QMMMGPOBSA-N 0.000 description 1
- QSKUTCRCDOEBKA-QMMMGPOBSA-N O[C@@H](Cc(cc1F)ccc1Br)C(O)=O Chemical compound O[C@@H](Cc(cc1F)ccc1Br)C(O)=O QSKUTCRCDOEBKA-QMMMGPOBSA-N 0.000 description 1
- AXBZSLGGZHZOFZ-FQEVSTJZSA-N O[C@@H](Cc1ccc(C2=CCOCC2)c(F)c1)C(OCc1ccccc1)=O Chemical compound O[C@@H](Cc1ccc(C2=CCOCC2)c(F)c1)C(OCc1ccccc1)=O AXBZSLGGZHZOFZ-FQEVSTJZSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K11/02—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/15—Depsipeptides; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Agronomy & Crop Science (AREA)
- Environmental Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562272040P | 2015-12-28 | 2015-12-28 | |
| US62/272,040 | 2015-12-28 | ||
| PCT/US2016/066497 WO2017116702A1 (en) | 2015-12-28 | 2016-12-14 | Anthelmintic depsipeptide compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019504050A JP2019504050A (ja) | 2019-02-14 |
| JP2019504050A5 JP2019504050A5 (enExample) | 2020-01-30 |
| JP6943859B2 true JP6943859B2 (ja) | 2021-10-06 |
Family
ID=57868331
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018534122A Expired - Fee Related JP6943859B2 (ja) | 2015-12-28 | 2016-12-14 | 駆虫性デプシペプチド化合物 |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US10344056B2 (enExample) |
| EP (1) | EP3397638B1 (enExample) |
| JP (1) | JP6943859B2 (enExample) |
| KR (2) | KR20220003663A (enExample) |
| CN (1) | CN108699052B (enExample) |
| AR (1) | AR107249A1 (enExample) |
| AU (2) | AU2016380868B2 (enExample) |
| BR (1) | BR112018013369A2 (enExample) |
| CA (1) | CA3009867C (enExample) |
| CL (1) | CL2018001744A1 (enExample) |
| CO (1) | CO2018006527A2 (enExample) |
| HK (1) | HK1255391A1 (enExample) |
| HU (1) | HUE065907T2 (enExample) |
| IL (1) | IL260262B2 (enExample) |
| MX (1) | MX2018007948A (enExample) |
| MY (1) | MY194716A (enExample) |
| NZ (1) | NZ743913A (enExample) |
| PH (1) | PH12018501367B1 (enExample) |
| RU (2) | RU2715556C2 (enExample) |
| SG (1) | SG11201805368YA (enExample) |
| TW (1) | TWI787165B (enExample) |
| UY (1) | UY37050A (enExample) |
| WO (1) | WO2017116702A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107835818B (zh) * | 2015-05-20 | 2022-04-29 | 勃林格殷格翰动物保健美国公司 | 驱虫缩酚酸肽化合物 |
| KR20220003663A (ko) | 2015-12-28 | 2022-01-10 | 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 | 구충성 뎁시펩티드 화합물 |
| WO2018039508A1 (en) | 2016-08-25 | 2018-03-01 | Merial, Inc. | Method for reducing unwanted effects in parasiticidal treatments |
| EP3541789A1 (en) | 2016-11-16 | 2019-09-25 | Boehringer Ingelheim Animal Health USA Inc. | Anthelmintic depsipeptide compounds |
| AU2018219273B2 (en) | 2017-02-08 | 2023-08-17 | Boehringer lngelheim Vetmedica GMBH | In vivo model for parasitic worm infection and methods for evaluating antiparasitic compounds, including compounds active against canine heartworm |
| EP3480195A1 (en) | 2017-11-07 | 2019-05-08 | Bayer Animal Health GmbH | Method for the synthesis of cyclic depsipeptides |
| CN111757880A (zh) | 2017-11-07 | 2020-10-09 | 拜耳动物保健有限责任公司 | 用于合成环状缩肽的方法 |
| JP7164608B2 (ja) * | 2017-11-29 | 2022-11-01 | ゾエティス・サービシーズ・エルエルシー | 内部寄生性デプシペプチド |
| EP3749096A1 (en) | 2018-02-08 | 2020-12-16 | Boehringer Ingelheim Animal Health USA Inc. | Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof |
| US20220071183A1 (en) | 2019-01-10 | 2022-03-10 | Zoetis Services Llc | Anthelmintic laboratory animal model for heartworm |
| JP7637630B2 (ja) | 2019-03-19 | 2025-02-28 | ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー | 駆虫性アザベンゾチオフェンおよびアザベンゾフラン化合物 |
| JP2023516754A (ja) * | 2020-03-06 | 2023-04-20 | ライフマックス ラボラトリーズ インコーポレイテッド | 環状デプシペプチドの局所医薬製剤 |
| PH12022553222A1 (en) | 2020-05-29 | 2024-02-12 | Boehringer Ingelheim Animal Health Usa Inc | Anthelmintic heterocyclic compounds |
| JP2024504208A (ja) | 2020-12-21 | 2024-01-30 | ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー | イソオキサゾリン化合物を含む殺寄生虫首輪 |
| JP7857414B2 (ja) | 2022-02-17 | 2026-05-12 | ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー | 流体製品メーラーを提供する方法及びシステム |
| AU2024339424A1 (en) * | 2023-09-15 | 2026-03-26 | Animol Discovery, Inc. | Antiparasitic cyclic depsipeptides |
| WO2025202940A2 (en) * | 2024-03-27 | 2025-10-02 | Animol Discovery, Inc. | Antiparasitic cyclic depsipeptides |
Family Cites Families (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO176766C (no) | 1989-02-07 | 1995-05-24 | Meiji Seika Kaisha | Fremgangsmåte for fremstilling av en forbindelse med anthelmintaktivitet |
| CA2132199C (en) | 1992-03-17 | 2000-01-18 | Hitoshi Nishiyama | Depsipeptide derivative, production thereof and use thereof |
| CN1073560C (zh) | 1993-02-19 | 2001-10-24 | 明治制果株式会社 | 环缩酚酸肽pf1022衍生物 |
| DE4317457A1 (de) | 1993-05-26 | 1994-12-01 | Bayer Ag | Octacyclodepsipeptide mit endoparasitizider Wirkung |
| DE4317432A1 (de) | 1993-05-26 | 1994-12-01 | Bayer Ag | Octacyclodepsipeptide mit endoparasitizider Wirkung |
| US5646244A (en) | 1993-09-06 | 1997-07-08 | Fujisawa Pharmaceutical Co., Ltd. | Cyclodepsipeptide compound |
| SE9303657D0 (sv) | 1993-11-05 | 1993-11-05 | Astra Ab | Short-acting dihydropyridines |
| DE4400464A1 (de) * | 1994-01-11 | 1995-07-13 | Bayer Ag | Endoparasitizide Mittel |
| DE4437198A1 (de) | 1994-10-18 | 1996-04-25 | Bayer Ag | Verfahren zur Sulfonylierung, Sulfenylierung und Phosphorylierung von cyclischen Depsipeptiden |
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