BR112018013369A2 - compostos depsipeptídicos anti-helmínticos - Google Patents

compostos depsipeptídicos anti-helmínticos

Info

Publication number
BR112018013369A2
BR112018013369A2 BR112018013369-8A BR112018013369A BR112018013369A2 BR 112018013369 A2 BR112018013369 A2 BR 112018013369A2 BR 112018013369 A BR112018013369 A BR 112018013369A BR 112018013369 A2 BR112018013369 A2 BR 112018013369A2
Authority
BR
Brazil
Prior art keywords
compounds
animals
depsipeptide compounds
compositions
birds
Prior art date
Application number
BR112018013369-8A
Other languages
English (en)
Inventor
Le Hir De Fallois Loic
Pacofsky Gregory
Long Alan
Meng Charles
Ik Lee Hyoung
Original Assignee
Merial, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial, Inc. filed Critical Merial, Inc.
Publication of BR112018013369A2 publication Critical patent/BR112018013369A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/15—Depsipeptides; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K11/02—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

a presente invenção fornece compostos depsipeptídicos cíclicos de fórmula (i) e composições compreendendo os compostos que são eficazes contra parasitas que prejudicam animais, incluindo humanos. os compostos e composições podem ser utilizados para combater parasitas no ou sobre animais, incluindo mamíferos e aves. a invenção também fornece um método melhorado para erradicar, controlar e prevenir a infestação de parasitas em animais, incluindo aves e mamíferos.
BR112018013369-8A 2015-12-28 2016-12-14 compostos depsipeptídicos anti-helmínticos BR112018013369A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562272040P 2015-12-28 2015-12-28
US62/272,040 2015-12-28
PCT/US2016/066497 WO2017116702A1 (en) 2015-12-28 2016-12-14 Anthelmintic depsipeptide compounds

Publications (1)

Publication Number Publication Date
BR112018013369A2 true BR112018013369A2 (pt) 2019-02-19

Family

ID=57868331

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018013369-8A BR112018013369A2 (pt) 2015-12-28 2016-12-14 compostos depsipeptídicos anti-helmínticos

Country Status (22)

Country Link
US (3) US10344056B2 (pt)
EP (1) EP3397638B1 (pt)
JP (1) JP6943859B2 (pt)
KR (2) KR102427124B1 (pt)
CN (1) CN108699052B (pt)
AR (1) AR107249A1 (pt)
AU (2) AU2016380868B2 (pt)
BR (1) BR112018013369A2 (pt)
CA (1) CA3009867C (pt)
CL (1) CL2018001744A1 (pt)
CO (1) CO2018006527A2 (pt)
HK (1) HK1255391A1 (pt)
IL (1) IL260262B2 (pt)
MX (1) MX2018007948A (pt)
MY (1) MY194716A (pt)
NZ (1) NZ743913A (pt)
PH (1) PH12018501367A1 (pt)
RU (2) RU2715556C2 (pt)
SG (1) SG11201805368YA (pt)
TW (1) TWI787165B (pt)
UY (1) UY37050A (pt)
WO (1) WO2017116702A1 (pt)

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KR102427124B1 (ko) 2015-12-28 2022-07-28 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 구충성 뎁시펩티드 화합물
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
WO2018093920A1 (en) 2016-11-16 2018-05-24 Merial, Inc. Anthelmintic depsipeptide compounds
PT3579696T (pt) 2017-02-08 2023-07-19 Boehringer Ingelheim Animal Health Usa Inc Modelo in vivo para infeção por vermes parasitários e métodos para avaliação de compostos antiparasíticos, que incluem compostos ativos contra a dirofilariose canina
EP3480195A1 (en) 2017-11-07 2019-05-08 Bayer Animal Health GmbH Method for the synthesis of cyclic depsipeptides
BR112020008933A2 (pt) 2017-11-07 2020-10-20 Bayer Animal Health Gmbh método para a síntese de depsipeptídeos cíclicos
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EP3908330A1 (en) 2019-01-10 2021-11-17 Zoetis Services LLC Anthelmintic laboratory animal model for heartworm
US11560388B2 (en) 2019-03-19 2023-01-24 Boehringer Ingelheim Vetmedica Gmbh Anthelmintic aza-benzothiophene and aza-benzofuran compounds
WO2021242581A1 (en) 2020-05-29 2021-12-02 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic heterocyclic compounds
CA3205997A1 (en) 2020-12-21 2022-06-30 University Of Georgia Research Foundation Inc. Parasiticidal collar comprising isoxazoline compounds
WO2023156938A1 (en) 2022-02-17 2023-08-24 Boehringer Ingelheim Vetmedica Gmbh Method and system for providing a fluid product mailer

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Also Published As

Publication number Publication date
RU2715556C2 (ru) 2020-03-02
MX2018007948A (es) 2018-08-01
US10344056B2 (en) 2019-07-09
AU2020200854A1 (en) 2020-02-27
HK1255391A1 (zh) 2019-08-16
TWI787165B (zh) 2022-12-21
US20220098241A1 (en) 2022-03-31
SG11201805368YA (en) 2018-07-30
KR20220003663A (ko) 2022-01-10
CN108699052A (zh) 2018-10-23
IL260262A (en) 2018-07-31
WO2017116702A1 (en) 2017-07-06
KR20180100349A (ko) 2018-09-10
CN108699052B (zh) 2022-04-29
IL260262B2 (en) 2023-06-01
EP3397638B1 (en) 2023-08-23
US12018048B2 (en) 2024-06-25
CA3009867A1 (en) 2017-07-06
US11230571B2 (en) 2022-01-25
NZ743913A (en) 2019-04-26
TW201726670A (zh) 2017-08-01
PH12018501367A1 (en) 2019-02-27
RU2018127195A (ru) 2020-01-30
KR102427124B1 (ko) 2022-07-28
AU2020200854B2 (en) 2021-08-05
AU2016380868B2 (en) 2019-11-28
MY194716A (en) 2022-12-15
CA3009867C (en) 2022-05-31
CL2018001744A1 (es) 2018-08-17
US20170233438A1 (en) 2017-08-17
JP2019504050A (ja) 2019-02-14
EP3397638A1 (en) 2018-11-07
US20190248840A1 (en) 2019-08-15
RU2018127195A3 (pt) 2020-01-30
CO2018006527A2 (es) 2018-07-10
AR107249A1 (es) 2018-04-11
AU2016380868A1 (en) 2018-07-19
RU2020107484A (ru) 2020-03-19
JP6943859B2 (ja) 2021-10-06
UY37050A (es) 2017-07-31

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B350 Update of information on the portal [chapter 15.35 patent gazette]
B25G Requested change of headquarter approved

Owner name: MERIAL, INC. (US)

B25A Requested transfer of rights approved

Owner name: BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC. (US)

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

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B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
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Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.