AR107249A1 - Compuestos depsipeptídicos como anthelmínticos - Google Patents
Compuestos depsipeptídicos como anthelmínticosInfo
- Publication number
- AR107249A1 AR107249A1 ARP160104061A ARP160104061A AR107249A1 AR 107249 A1 AR107249 A1 AR 107249A1 AR P160104061 A ARP160104061 A AR P160104061A AR P160104061 A ARP160104061 A AR P160104061A AR 107249 A1 AR107249 A1 AR 107249A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- members
- haloalkyl
- membered
- ring
- Prior art date
Links
- OHRURASPPZQGQM-GCCNXGTGSA-N romidepsin Chemical class O1C(=O)[C@H](C(C)C)NC(=O)C(=C/C)/NC(=O)[C@H]2CSSCC\C=C\[C@@H]1CC(=O)N[C@H](C(C)C)C(=O)N2 OHRURASPPZQGQM-GCCNXGTGSA-N 0.000 title abstract 2
- -1 carbocycle Chemical group 0.000 abstract 57
- 125000000623 heterocyclic group Chemical group 0.000 abstract 48
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 46
- 125000004414 alkyl thio group Chemical group 0.000 abstract 32
- 229910052739 hydrogen Inorganic materials 0.000 abstract 32
- 239000001257 hydrogen Substances 0.000 abstract 32
- 125000006583 (C1-C3) haloalkyl group Chemical group 0.000 abstract 31
- 125000003545 alkoxy group Chemical group 0.000 abstract 31
- 125000003282 alkyl amino group Chemical group 0.000 abstract 31
- 125000002837 carbocyclic group Chemical group 0.000 abstract 31
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 31
- 125000004438 haloalkoxy group Chemical group 0.000 abstract 31
- 125000004995 haloalkylthio group Chemical group 0.000 abstract 31
- 229910052736 halogen Inorganic materials 0.000 abstract 31
- 150000002367 halogens Chemical group 0.000 abstract 31
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 31
- 125000005083 alkoxyalkoxy group Chemical group 0.000 abstract 29
- 125000004644 alkyl sulfinyl group Chemical group 0.000 abstract 29
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 29
- 125000004440 haloalkylsulfinyl group Chemical group 0.000 abstract 29
- 125000004441 haloalkylsulfonyl group Chemical group 0.000 abstract 29
- 125000004043 oxo group Chemical group O=* 0.000 abstract 29
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 26
- 125000000217 alkyl group Chemical group 0.000 abstract 19
- 125000003118 aryl group Chemical group 0.000 abstract 18
- 125000001188 haloalkyl group Chemical group 0.000 abstract 18
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 17
- 125000001072 heteroaryl group Chemical group 0.000 abstract 17
- 125000001424 substituent group Chemical group 0.000 abstract 17
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 15
- 125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 14
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 241001465754 Metazoa Species 0.000 abstract 3
- 125000003342 alkenyl group Chemical group 0.000 abstract 3
- 125000000304 alkynyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 3
- 125000000262 haloalkenyl group Chemical group 0.000 abstract 3
- 125000000232 haloalkynyl group Chemical group 0.000 abstract 3
- 244000045947 parasite Species 0.000 abstract 3
- HCMJWOGOISXSDL-UHFFFAOYSA-N (2-isothiocyanato-1-phenylethyl)benzene Chemical group C=1C=CC=CC=1C(CN=C=S)C1=CC=CC=C1 HCMJWOGOISXSDL-UHFFFAOYSA-N 0.000 abstract 2
- KHEPSBKTSMKGQV-UHFFFAOYSA-N 3-[4-[2-(4-piperidin-4-ylanilino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]pyrazol-1-yl]propanenitrile Chemical group N1CCC(CC1)C1=CC=C(C=C1)NC=1N=C(C2=C(N=1)NC=C2)C=1C=NN(C=1)CCC#N KHEPSBKTSMKGQV-UHFFFAOYSA-N 0.000 abstract 2
- 108010002156 Depsipeptides Proteins 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 2
- 125000004404 heteroalkyl group Chemical group 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 206010061217 Infestation Diseases 0.000 abstract 1
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
- 125000006350 alkyl thio alkyl group Chemical group 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000004001 thioalkyl group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/15—Depsipeptides; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K11/02—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Agronomy & Crop Science (AREA)
- Environmental Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562272040P | 2015-12-28 | 2015-12-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR107249A1 true AR107249A1 (es) | 2018-04-11 |
Family
ID=57868331
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP160104061A AR107249A1 (es) | 2015-12-28 | 2016-12-28 | Compuestos depsipeptídicos como anthelmínticos |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US10344056B2 (enExample) |
| EP (1) | EP3397638B1 (enExample) |
| JP (1) | JP6943859B2 (enExample) |
| KR (2) | KR102427124B1 (enExample) |
| CN (1) | CN108699052B (enExample) |
| AR (1) | AR107249A1 (enExample) |
| AU (2) | AU2016380868B2 (enExample) |
| BR (1) | BR112018013369A2 (enExample) |
| CA (1) | CA3009867C (enExample) |
| CL (1) | CL2018001744A1 (enExample) |
| CO (1) | CO2018006527A2 (enExample) |
| HK (1) | HK1255391A1 (enExample) |
| HU (1) | HUE065907T2 (enExample) |
| IL (1) | IL260262B2 (enExample) |
| MX (1) | MX2018007948A (enExample) |
| MY (1) | MY194716A (enExample) |
| NZ (1) | NZ743913A (enExample) |
| PH (1) | PH12018501367B1 (enExample) |
| RU (2) | RU2715556C2 (enExample) |
| SG (1) | SG11201805368YA (enExample) |
| TW (1) | TWI787165B (enExample) |
| UY (1) | UY37050A (enExample) |
| WO (1) | WO2017116702A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE055535T2 (hu) * | 2015-05-20 | 2021-12-28 | Boehringer Ingelheim Animal Health Usa Inc | Féreghajtó depszipeptid-vegyületek |
| CN108699052B (zh) | 2015-12-28 | 2022-04-29 | 勃林格殷格翰动物保健美国公司 | 驱虫缩酚酸肽化合物 |
| WO2018039508A1 (en) | 2016-08-25 | 2018-03-01 | Merial, Inc. | Method for reducing unwanted effects in parasiticidal treatments |
| JP2020504710A (ja) | 2016-11-16 | 2020-02-13 | ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド | 駆虫性デプシペプチド化合物 |
| PT3579696T (pt) | 2017-02-08 | 2023-07-19 | Boehringer Ingelheim Animal Health Usa Inc | Modelo in vivo para infeção por vermes parasitários e métodos para avaliação de compostos antiparasíticos, que incluem compostos ativos contra a dirofilariose canina |
| EP3480195A1 (en) | 2017-11-07 | 2019-05-08 | Bayer Animal Health GmbH | Method for the synthesis of cyclic depsipeptides |
| WO2019091975A1 (en) | 2017-11-07 | 2019-05-16 | Bayer Animal Health Gmbh | Method for the synthesis of cyclic depsipeptides |
| NZ764359A (en) * | 2017-11-29 | 2023-03-31 | Zoetis Services Llc | Endoparasitic depsipeptides |
| WO2019157241A1 (en) | 2018-02-08 | 2019-08-15 | Boehringer Ingelheim Animal Health USA Inc. | Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof |
| AU2020205960B2 (en) | 2019-01-10 | 2024-04-18 | Zoetis Services Llc | Anthelmintic laboratory animal model for heartworm |
| WO2020191091A1 (en) | 2019-03-19 | 2020-09-24 | Boehringer Ingelheim Animal Health USA Inc. | Anthelmintic aza-benzothiophene and aza-benzofuran compounds |
| EP4114358A4 (en) * | 2020-03-06 | 2024-03-27 | Lifemax Laboratories, Inc. | TOPICAL PHARMACEUTICAL FORMULATIONS OF A CYCLIC DEPSIPEPTIDE |
| US11964977B2 (en) | 2020-05-29 | 2024-04-23 | Boehringer Ingelheim Animal Health USA Inc. | Anthelmintic heterocyclic compounds |
| US12161089B2 (en) | 2020-12-21 | 2024-12-10 | Boehringer Ingelheim Animal Health USA Inc. | Parasiticidal collar comprising isoxazoline compounds |
| US12258193B2 (en) | 2022-02-17 | 2025-03-25 | Boehringer Ingelheim Vetmedica Gmbh | Method and system for providing a fluid product mailer |
| WO2025057117A1 (en) * | 2023-09-15 | 2025-03-20 | Animol Discovery, Inc. | Antiparasitic cyclic depsipeptides |
Family Cites Families (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO176766C (no) | 1989-02-07 | 1995-05-24 | Meiji Seika Kaisha | Fremgangsmåte for fremstilling av en forbindelse med anthelmintaktivitet |
| NZ249588A (en) | 1992-03-17 | 1996-08-27 | Fujisawa Pharmaceutical Co | Anthelmintic agent |
| AU695021B2 (en) | 1993-02-19 | 1998-08-06 | Meiji Seika Kaisha Ltd. | PF1022 derivative cyclic depsipeptide |
| DE4317432A1 (de) | 1993-05-26 | 1994-12-01 | Bayer Ag | Octacyclodepsipeptide mit endoparasitizider Wirkung |
| DE4317457A1 (de) | 1993-05-26 | 1994-12-01 | Bayer Ag | Octacyclodepsipeptide mit endoparasitizider Wirkung |
| CN1061039C (zh) | 1993-09-06 | 2001-01-24 | 藤泽药品工业株式会社 | 环状缩酚酸肽化合物或其盐及其制备方法和用途 |
| SE9303657D0 (sv) | 1993-11-05 | 1993-11-05 | Astra Ab | Short-acting dihydropyridines |
| DE4400464A1 (de) * | 1994-01-11 | 1995-07-13 | Bayer Ag | Endoparasitizide Mittel |
| DE4437198A1 (de) | 1994-10-18 | 1996-04-25 | Bayer Ag | Verfahren zur Sulfonylierung, Sulfenylierung und Phosphorylierung von cyclischen Depsipeptiden |
| DE19520275A1 (de) | 1995-06-02 | 1996-12-05 | Bayer Ag | Endoparasitizide Mittel |
| NZ318515A (en) * | 1995-09-22 | 2000-05-26 | Bayer Ag | Cyclodepsipeptide PF1022 derivatives and compositions thereof |
| US6235875B1 (en) | 1996-10-07 | 2001-05-22 | Fujisawa Pharmaceutical Co., Ltd. | Process for producing depsipeptide derivatives and novel intermediates therefor |
| DE19713626A1 (de) | 1997-04-02 | 1998-10-08 | Bayer Ag | Neue Thiodepsipeptide zur Bekämpfung von Endoparasiten und ein einfaches Verfahren zu ihrer Herstellung |
| BR9810412A (pt) | 1997-06-04 | 2000-08-22 | Bayer Ag | Desoxiciclodepsipeptìdios e seu emprego para o combate de endoparasitas |
| DE19811559A1 (de) | 1998-03-17 | 1999-09-23 | Bayer Ag | Cyclooctadepsipeptide |
| DE19828043A1 (de) | 1998-06-24 | 1999-12-30 | Bayer Ag | Ektoparasitizide Mittel |
| DE19921887A1 (de) * | 1999-05-12 | 2000-11-16 | Bayer Ag | Endoparasitizide Mittel |
| DE19962145A1 (de) | 1999-12-22 | 2001-06-28 | Bayer Ag | Schädlingsbekämpfungsmittel/Depsipeptide |
| DE19962147A1 (de) | 1999-12-22 | 2001-06-28 | Bayer Ag | Schädlingsbekämpfungsmittel / PF 1022-221 |
| DE10008128A1 (de) | 2000-02-22 | 2001-08-23 | Bayer Ag | Endoparasitizide Mittel |
| DE10031044A1 (de) | 2000-06-26 | 2002-01-03 | Bayer Ag | Endoparasitizide Mittel zur freiwilligen oralen Aufnahme durch Tiere |
| DE10104362A1 (de) | 2001-02-01 | 2002-08-08 | Bayer Ag | Kristallmodifikation eines cyclischen Depsipeptids mit besserer Wirksamkeit |
| UY26592A1 (es) | 2001-02-20 | 2001-09-28 | Bayer Ag | Agentes endoparasiticidas |
| US6893652B2 (en) * | 2001-08-27 | 2005-05-17 | Wyeth | Endoparasiticidal gel composition |
| US20040236191A1 (en) | 2003-05-19 | 2004-11-25 | Poliska Steven A. | System and method for identifying and labeling livestock products, and managing data associated with those products |
| DE10358525A1 (de) | 2003-12-13 | 2005-07-07 | Bayer Healthcare Ag | Endoparasitizide Mittel zur topischen Applikation |
| ES2351972T3 (es) | 2004-02-27 | 2011-02-14 | Ic Services | Procedimiento y set para la identificación de animales. |
| DE102004055316A1 (de) | 2004-11-16 | 2006-05-18 | Bayer Healthcare Ag | Verhinderung vertikaler Endoparasiten-Infektionen |
| US20060202835A1 (en) | 2005-02-25 | 2006-09-14 | Osborne Industries, Inc. | Dual frequency identification device |
| DE102008022520A1 (de) | 2008-05-07 | 2009-11-12 | Bayer Animal Health Gmbh | Feste Arzneimittelformulierung mit verzögerter Freisetzung |
| DE102008030764A1 (de) | 2008-06-28 | 2009-12-31 | Bayer Animal Health Gmbh | Kombination von Amidin-Derivaten mit cyclischen Depsipeptiden |
| DE102008031284A1 (de) | 2008-07-02 | 2010-01-07 | Bayer Schering Pharma Aktiengesellschaft | Neue Bekämpfungsmöglichkeit der Giardiose |
| DE102008031283A1 (de) | 2008-07-02 | 2010-01-07 | Bayer Schering Pharma Aktiengesellschaft | Neue Bekämpfungsmöglichkeit von durch Trichomonadida hervorgerufenen Krankheiten |
| EP2379731A1 (de) | 2008-12-16 | 2011-10-26 | Bayer Animal Health GmbH | Verfahren zur herstellung milchsäure- und phenylmilchsäurehaltiger optisch aktiver, cyclischer depsipeptide mit 24 ringatomen mit hilfe von pilzstämmen der art rosellinia sowie weiteren gattungen xylariaceen |
| KR101002530B1 (ko) | 2009-02-18 | 2010-12-17 | 삼성에스디아이 주식회사 | 알에프아이디 통신 장치 |
| US20120302496A1 (en) | 2009-12-11 | 2012-11-29 | Bayer Intellectual Property Gmbh | Novel 24-membered cyclooctadepsipeptides from fungal strains and their use as anthelmintics or endoparasiticides |
| WO2012028556A1 (en) | 2010-08-31 | 2012-03-08 | Bayer Animal Health Gmbh | Macrocyclic lactones and their use and their combinations with other active substances |
| WO2012065031A2 (en) | 2010-11-11 | 2012-05-18 | Mlp Technology Inc. | Animal data management |
| US9848290B2 (en) | 2011-03-10 | 2017-12-19 | Aruba Networks, Inc. | Location based computerized system and method thereof |
| MX356094B (es) | 2011-12-21 | 2018-05-14 | Bayer Ip Gmbh | Preparaciones que comprenden emodepsido amorfo. |
| JP6300207B2 (ja) | 2012-06-13 | 2018-03-28 | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | 新規環状デプシペプチド誘導体およびそれを含んでなる有害生物防除剤 |
| US20140306005A1 (en) | 2013-04-14 | 2014-10-16 | Forever Yours, Inc. | Method for Data Transport and Recovery of Dependent Creatures |
| HUE055535T2 (hu) * | 2015-05-20 | 2021-12-28 | Boehringer Ingelheim Animal Health Usa Inc | Féreghajtó depszipeptid-vegyületek |
| CN108699052B (zh) | 2015-12-28 | 2022-04-29 | 勃林格殷格翰动物保健美国公司 | 驱虫缩酚酸肽化合物 |
| JP2020504710A (ja) | 2016-11-16 | 2020-02-13 | ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド | 駆虫性デプシペプチド化合物 |
-
2016
- 2016-12-14 CN CN201680082548.2A patent/CN108699052B/zh not_active Expired - Fee Related
- 2016-12-14 BR BR112018013369-8A patent/BR112018013369A2/pt not_active Application Discontinuation
- 2016-12-14 HK HK18114530.8A patent/HK1255391A1/zh unknown
- 2016-12-14 SG SG11201805368YA patent/SG11201805368YA/en unknown
- 2016-12-14 RU RU2018127195A patent/RU2715556C2/ru active
- 2016-12-14 MY MYPI2018001112A patent/MY194716A/en unknown
- 2016-12-14 HU HUE16829348A patent/HUE065907T2/hu unknown
- 2016-12-14 JP JP2018534122A patent/JP6943859B2/ja not_active Expired - Fee Related
- 2016-12-14 US US15/378,219 patent/US10344056B2/en active Active
- 2016-12-14 KR KR1020187021726A patent/KR102427124B1/ko active Active
- 2016-12-14 MX MX2018007948A patent/MX2018007948A/es unknown
- 2016-12-14 CA CA3009867A patent/CA3009867C/en active Active
- 2016-12-14 NZ NZ743913A patent/NZ743913A/en not_active IP Right Cessation
- 2016-12-14 WO PCT/US2016/066497 patent/WO2017116702A1/en not_active Ceased
- 2016-12-14 PH PH1/2018/501367A patent/PH12018501367B1/en unknown
- 2016-12-14 EP EP16829348.8A patent/EP3397638B1/en active Active
- 2016-12-14 AU AU2016380868A patent/AU2016380868B2/en not_active Ceased
- 2016-12-14 RU RU2020107484A patent/RU2020107484A/ru unknown
- 2016-12-14 KR KR1020217043332A patent/KR20220003663A/ko not_active Abandoned
- 2016-12-26 UY UY0001037050A patent/UY37050A/es not_active Application Discontinuation
- 2016-12-28 AR ARP160104061A patent/AR107249A1/es not_active Application Discontinuation
- 2016-12-28 TW TW105143547A patent/TWI787165B/zh not_active IP Right Cessation
-
2018
- 2018-06-25 IL IL260262A patent/IL260262B2/en unknown
- 2018-06-25 CO CONC2018/0006527A patent/CO2018006527A2/es unknown
- 2018-06-25 CL CL2018001744A patent/CL2018001744A1/es unknown
-
2019
- 2019-04-23 US US16/392,412 patent/US11230571B2/en active Active
-
2020
- 2020-02-06 AU AU2020200854A patent/AU2020200854B2/en not_active Ceased
-
2021
- 2021-12-08 US US17/643,251 patent/US12018048B2/en active Active
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