JP6843750B2 - 哺乳類細胞の培養方法 - Google Patents

哺乳類細胞の培養方法 Download PDF

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JP6843750B2
JP6843750B2 JP2017533539A JP2017533539A JP6843750B2 JP 6843750 B2 JP6843750 B2 JP 6843750B2 JP 2017533539 A JP2017533539 A JP 2017533539A JP 2017533539 A JP2017533539 A JP 2017533539A JP 6843750 B2 JP6843750 B2 JP 6843750B2
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cells
days
concentration
liquid medium
approximately
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JP2017538435A (ja
JP2017538435A5 (esLanguage
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クリストファー・ウォン
ティモシー・ジョンソン
ジェイソン・ウォルサー
チェン・チェン
ジョナサン・ワン
ネハー・シャー
ぺ・ソル−ア
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Genzyme Corp
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0681—Cells of the genital tract; Non-germinal cells from gonads
    • C12N5/0682—Cells of the female genital tract, e.g. endometrium; Non-germinal cells from ovaries, e.g. ovarian follicle cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/04—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by injection or suction, e.g. using pipettes, syringes, needles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/0043—Medium free of human- or animal-derived components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/005—Protein-free medium
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/50—Soluble polymers, e.g. polyethyleneglycol [PEG]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production

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  • Health & Medical Sciences (AREA)
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  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
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  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Sustainable Development (AREA)
  • Reproductive Health (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2017533539A 2014-12-22 2015-12-21 哺乳類細胞の培養方法 Active JP6843750B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462095734P 2014-12-22 2014-12-22
US62/095,734 2014-12-22
PCT/US2015/067040 WO2016106192A2 (en) 2014-12-22 2015-12-21 Methods of culturing a mammalian cell

Related Child Applications (1)

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JP2020177700A Division JP7075463B2 (ja) 2014-12-22 2020-10-23 哺乳類細胞の培養方法

Publications (3)

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JP2017538435A JP2017538435A (ja) 2017-12-28
JP2017538435A5 JP2017538435A5 (esLanguage) 2019-01-31
JP6843750B2 true JP6843750B2 (ja) 2021-03-17

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JP2020177700A Active JP7075463B2 (ja) 2014-12-22 2020-10-23 哺乳類細胞の培養方法
JP2022079207A Pending JP2022107000A (ja) 2014-12-22 2022-05-13 哺乳類細胞の培養方法
JP2024014536A Pending JP2024050754A (ja) 2014-12-22 2024-02-02 哺乳類細胞の培養方法

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JP2022079207A Pending JP2022107000A (ja) 2014-12-22 2022-05-13 哺乳類細胞の培養方法
JP2024014536A Pending JP2024050754A (ja) 2014-12-22 2024-02-02 哺乳類細胞の培養方法

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Country Link
US (2) US11306341B2 (esLanguage)
EP (1) EP3237604B1 (esLanguage)
JP (4) JP6843750B2 (esLanguage)
KR (3) KR20250025516A (esLanguage)
CN (1) CN107567495A (esLanguage)
AU (3) AU2015369809B2 (esLanguage)
BR (1) BR112017013423B1 (esLanguage)
CA (2) CA3225136A1 (esLanguage)
HK (1) HK1246345A1 (esLanguage)
IL (2) IL308064A (esLanguage)
MX (2) MX383857B (esLanguage)
RU (1) RU2712746C2 (esLanguage)
SG (2) SG10202001034PA (esLanguage)
TW (3) TWI751103B (esLanguage)
WO (1) WO2016106192A2 (esLanguage)

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Publication number Publication date
JP7075463B2 (ja) 2022-05-25
AU2025201416A1 (en) 2025-03-20
IL253071B2 (en) 2024-04-01
EP3237604B1 (en) 2026-02-11
MX2017008338A (es) 2017-10-19
US11306341B2 (en) 2022-04-19
RU2020101112A (ru) 2020-03-13
RU2017126045A (ru) 2019-01-24
HK1246345A1 (zh) 2018-09-07
AU2022204152B2 (en) 2024-11-28
CA3225136A1 (en) 2016-06-30
US20160177361A1 (en) 2016-06-23
RU2712746C2 (ru) 2020-01-30
CA2971861A1 (en) 2016-06-30
KR102568951B1 (ko) 2023-08-22
CA2971861C (en) 2024-02-13
SG11201705103WA (en) 2017-07-28
IL253071A0 (en) 2017-08-31
TWI751103B (zh) 2022-01-01
KR20230125102A (ko) 2023-08-28
MX2021007433A (es) 2021-08-05
IL308064A (en) 2023-12-01
TW201639881A (zh) 2016-11-16
EP3237604A2 (en) 2017-11-01
BR112017013423B1 (pt) 2023-04-11
TWI843012B (zh) 2024-05-21
US12486524B2 (en) 2025-12-02
AU2022204152A1 (en) 2022-06-30
WO2016106192A3 (en) 2016-11-03
KR102769649B1 (ko) 2025-02-19
JP2021019624A (ja) 2021-02-18
RU2017126045A3 (esLanguage) 2019-06-24
AU2015369809A1 (en) 2017-08-10
JP2017538435A (ja) 2017-12-28
US20220145348A1 (en) 2022-05-12
TW202106706A (zh) 2021-02-16
BR112017013423A2 (pt) 2018-01-09
MX383857B (es) 2025-03-14
JP2022107000A (ja) 2022-07-20
KR20170090508A (ko) 2017-08-07
TWI741851B (zh) 2021-10-01
KR20250025516A (ko) 2025-02-21
WO2016106192A2 (en) 2016-06-30
CN107567495A (zh) 2018-01-09
JP2024050754A (ja) 2024-04-10
TW202200785A (zh) 2022-01-01
IL253071B1 (en) 2023-12-01
SG10202001034PA (en) 2020-04-29
AU2015369809B2 (en) 2022-03-17

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