SG11201705103WA - Methods of culturing a mammalian cell - Google Patents
Methods of culturing a mammalian cellInfo
- Publication number
- SG11201705103WA SG11201705103WA SG11201705103WA SG11201705103WA SG11201705103WA SG 11201705103W A SG11201705103W A SG 11201705103WA SG 11201705103W A SG11201705103W A SG 11201705103WA SG 11201705103W A SG11201705103W A SG 11201705103WA SG 11201705103W A SG11201705103W A SG 11201705103WA
- Authority
- SG
- Singapore
- Prior art keywords
- culturing
- methods
- mammalian cell
- mammalian
- cell
- Prior art date
Links
- 238000012258 culturing Methods 0.000 title 1
- 210000004962 mammalian cell Anatomy 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0681—Cells of the genital tract; Non-germinal cells from gonads
- C12N5/0682—Cells of the female genital tract, e.g. endometrium; Non-germinal cells from ovaries, e.g. ovarian follicle cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/0043—Medium free of human- or animal-derived components
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/005—Protein-free medium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2465—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1) acting on alpha-galactose-glycoside bonds, e.g. alpha-galactosidase (3.2.1.22)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/50—Soluble polymers, e.g. polyethyleneglycol [PEG]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01022—Alpha-galactosidase (3.2.1.22)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Reproductive Health (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462095734P | 2014-12-22 | 2014-12-22 | |
| PCT/US2015/067040 WO2016106192A2 (en) | 2014-12-22 | 2015-12-21 | Methods of culturing a mammalian cell |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201705103WA true SG11201705103WA (en) | 2017-07-28 |
Family
ID=55527619
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201705103WA SG11201705103WA (en) | 2014-12-22 | 2015-12-21 | Methods of culturing a mammalian cell |
| SG10202001034PA SG10202001034PA (en) | 2014-12-22 | 2015-12-21 | Methods of culturing a mammalian cell |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10202001034PA SG10202001034PA (en) | 2014-12-22 | 2015-12-21 | Methods of culturing a mammalian cell |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US11306341B2 (en) |
| EP (1) | EP3237604A2 (en) |
| JP (4) | JP6843750B2 (en) |
| KR (2) | KR20230125102A (en) |
| CN (1) | CN107567495A (en) |
| AU (2) | AU2015369809B2 (en) |
| BR (1) | BR112017013423B1 (en) |
| CA (2) | CA3225136A1 (en) |
| HK (1) | HK1246345A1 (en) |
| IL (2) | IL308064A (en) |
| MX (2) | MX2017008338A (en) |
| RU (1) | RU2712746C2 (en) |
| SG (2) | SG11201705103WA (en) |
| TW (2) | TWI741851B (en) |
| WO (1) | WO2016106192A2 (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX367025B (en) | 2013-02-22 | 2019-08-02 | Genzyme Corp | Microcarrier perfusion culturing methods and uses thereof. |
| ES2717927T3 (en) | 2013-02-22 | 2019-06-26 | Genzyme Corp | Cultivation procedures by perfusion of microcarriers and uses thereof |
| TWI743024B (en) | 2014-06-06 | 2021-10-21 | 美商健臻公司 | Perfusion culturing methods and uses thereof |
| TWI776235B (en) | 2014-06-09 | 2022-09-01 | 美商健臻公司 | Seed train processes and uses thereof |
| BR112017013423B1 (en) | 2014-12-22 | 2023-04-11 | Genzyme Corporation | MAMMALIAN CELL CULTIVATION METHODS |
| BR112020018823A2 (en) | 2018-03-16 | 2021-02-09 | Genzyme Corporation | methods to improve cell viability in a production bioreactor |
| WO2022035973A1 (en) * | 2020-08-12 | 2022-02-17 | Allen Institute | Systems, devices, and methods for quality control of cell production using predictive tagging |
| CN112795531B (en) * | 2021-04-11 | 2021-08-06 | 依科赛生物科技（太仓）有限公司 | CHO cell serum-free and protein-free culture medium and application thereof |
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| US6458574B1 (en) * | 1996-09-12 | 2002-10-01 | Transkaryotic Therapies, Inc. | Treatment of a α-galactosidase a deficiency |
| ES2276853T3 (en) | 2000-12-20 | 2007-07-01 | Bayer Pharmaceuticals Corporation | DEVICE AND PROCEDURE FOR SERIAL EXPANSION OF MAMMER CELL SEEDS. |
| WO2003039459A2 (en) | 2001-11-05 | 2003-05-15 | Genvec, Inc. | Viral vector production methods and compositions |
| US6953692B2 (en) | 2001-12-18 | 2005-10-11 | Bayer Pharmaceuticals Corporation | Device and method for seed-train expansion of mammalian cells |
| US7067279B1 (en) * | 2002-08-23 | 2006-06-27 | Immunex Corporation | Cell culture performance with betaine |
| US6974681B1 (en) * | 2002-08-23 | 2005-12-13 | Immunex Corporation | Cell culture performance with vanadate |
| FR2866655B1 (en) | 2004-02-20 | 2007-05-11 | Cesco Bioengineering Co Ltd | APPARATUS AND METHOD FOR THE PREPARATION AND CULTIVATION OF CELLS |
| WO2006033935A2 (en) | 2004-09-16 | 2006-03-30 | Becton, Dickinson And Company | Perfusion bioreactor for culturing cells |
| JP2008543307A (en) | 2005-06-15 | 2008-12-04 | アンプロテイン コーポレイション | Suspension culture vessel |
| WO2006138143A1 (en) | 2005-06-15 | 2006-12-28 | Amprotein Corporation | Suspension culture vessels |
| US20080206819A1 (en) * | 2006-08-21 | 2008-08-28 | Mary Tsao | Intensified Perfusion Production Method |
| US8501462B2 (en) | 2007-02-27 | 2013-08-06 | The Board Of Trustees Of The University Of Illinois | Insert device for multiwell plate |
| WO2009034186A2 (en) | 2007-09-13 | 2009-03-19 | Helmholtz-Zentrum für Infektionsforschung GmbH | Process for cell cultivation |
| DK2205244T3 (en) | 2007-11-08 | 2013-11-25 | Ambit Biosciences Corp | METHODS FOR ADMINISTRATING N- (5-TERT-BUTYL-ISOXAZOL-3-YL) -N '- {4- [7- (2-MORPHOLIN-4-YL-ETHOXY-) IMIDAZO- [2,1-B] - [1,3] -BENZOTHIAZOL-2-YL] -PHENYL} URINE FOR TREATMENT OF PROLIFERATIVE DISEASE |
| CN110066782B (en) * | 2007-12-31 | 2024-04-16 | 武田药品工业株式会社 | Recombinant furin substantially free of animal proteins and method for producing same |
| US20090233334A1 (en) * | 2008-03-11 | 2009-09-17 | Excellgene Sa | Cell cultivation and production of recombinant proteins by means of an orbital shake bioreactor system with disposable bags at the 1,500 liter scale |
| DE102008019691A1 (en) | 2008-04-15 | 2009-10-29 | Technische Universität Ilmenau | Semi-active microfluidic system for 3D cell culture as well as procedures for its perfusion |
| US8728479B2 (en) | 2009-03-31 | 2014-05-20 | The Trustees Of The University Of Pennsylvania | Antigen-binding proteins comprising recombinant protein scaffolds |
| US8765415B2 (en) * | 2009-11-17 | 2014-07-01 | Medarex, L.L.C. | Methods for enhanced protein production |
| EP2707488B1 (en) | 2011-05-12 | 2017-11-15 | ProBioGen AG | Enhancement of protein production yield mediated by a fast shuttling cdc42 gtpase |
| US20150004686A1 (en) | 2012-02-02 | 2015-01-01 | Corning Incorporated | Automatic continuous perfusion cell culture microplate consumables |
| EP2834649A4 (en) | 2012-04-01 | 2015-12-09 | Emd Millipore Corp | Cell culture and gradient migration assay methods and devices |
| WO2014066519A1 (en) | 2012-10-23 | 2014-05-01 | Genzyme Corporation | Perfusion culturing methods and uses thereof |
| ES2717927T3 (en) | 2013-02-22 | 2019-06-26 | Genzyme Corp | Cultivation procedures by perfusion of microcarriers and uses thereof |
| MX367025B (en) | 2013-02-22 | 2019-08-02 | Genzyme Corp | Microcarrier perfusion culturing methods and uses thereof. |
| RU2768003C2 (en) | 2013-03-08 | 2022-03-22 | Джензим Корпорейшн | Integrated continuous production of therapeutic protein-based medicinal agents |
| WO2014151901A1 (en) * | 2013-03-14 | 2014-09-25 | Abbvie Inc. | Improvement of mammalian cell culture performance through surfactant supplementation of feed media |
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| WO2014194137A1 (en) * | 2013-05-29 | 2014-12-04 | Biogen Idec Ma Inc. | Methods of evaluating cell culture additives |
| EP3047013B1 (en) | 2013-09-16 | 2021-08-18 | Genzyme Corporation | Methods and systems for processing a cell culture |
| TWI709569B (en) | 2014-01-17 | 2020-11-11 | 美商健臻公司 | Sterile chromatography resin and use thereof in manufacturing processes |
| TWI671312B (en) | 2014-01-17 | 2019-09-11 | 美商健臻公司 | Sterile chromatography and manufacturing processes |
| ES2709994T3 (en) * | 2014-06-04 | 2019-04-22 | Amgen Inc | Collection methods in mammalian cell cultures |
| TWI743024B (en) | 2014-06-06 | 2021-10-21 | 美商健臻公司 | Perfusion culturing methods and uses thereof |
| TWI776235B (en) | 2014-06-09 | 2022-09-01 | 美商健臻公司 | Seed train processes and uses thereof |
| BR112017013423B1 (en) | 2014-12-22 | 2023-04-11 | Genzyme Corporation | MAMMALIAN CELL CULTIVATION METHODS |
-
2015
- 2015-12-21 BR BR112017013423-3A patent/BR112017013423B1/en active IP Right Grant
- 2015-12-21 AU AU2015369809A patent/AU2015369809B2/en active Active
- 2015-12-21 SG SG11201705103WA patent/SG11201705103WA/en unknown
- 2015-12-21 SG SG10202001034PA patent/SG10202001034PA/en unknown
- 2015-12-21 CN CN201580076640.3A patent/CN107567495A/en active Pending
- 2015-12-21 KR KR1020237027804A patent/KR20230125102A/en not_active Application Discontinuation
- 2015-12-21 US US14/976,486 patent/US11306341B2/en active Active
- 2015-12-21 JP JP2017533539A patent/JP6843750B2/en active Active
- 2015-12-21 KR KR1020177020466A patent/KR102568951B1/en active IP Right Grant
- 2015-12-21 RU RU2017126045A patent/RU2712746C2/en active
- 2015-12-21 CA CA3225136A patent/CA3225136A1/en active Pending
- 2015-12-21 CA CA2971861A patent/CA2971861C/en active Active
- 2015-12-21 IL IL308064A patent/IL308064A/en unknown
- 2015-12-21 WO PCT/US2015/067040 patent/WO2016106192A2/en active Application Filing
- 2015-12-21 EP EP15843061.1A patent/EP3237604A2/en active Pending
- 2015-12-21 IL IL253071A patent/IL253071B2/en unknown
- 2015-12-21 MX MX2017008338A patent/MX2017008338A/en unknown
- 2015-12-22 TW TW109136823A patent/TWI741851B/en active
- 2015-12-22 TW TW104143177A patent/TWI751103B/en active
-
2017
- 2017-06-21 MX MX2021007433A patent/MX2021007433A/en unknown
-
2018
- 2018-04-30 HK HK18105611.8A patent/HK1246345A1/en unknown
-
2020
- 2020-10-23 JP JP2020177700A patent/JP7075463B2/en active Active
-
2022
- 2022-01-11 US US17/572,978 patent/US20220145348A1/en active Pending
- 2022-05-13 JP JP2022079207A patent/JP2022107000A/en active Pending
- 2022-06-14 AU AU2022204152A patent/AU2022204152A1/en active Pending
-
2024
- 2024-02-02 JP JP2024014536A patent/JP2024050754A/en active Pending
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