HK1246345A1 - 培養哺乳動物細胞的方法 - Google Patents

培養哺乳動物細胞的方法

Info

Publication number
HK1246345A1
HK1246345A1 HK18105611.8A HK18105611A HK1246345A1 HK 1246345 A1 HK1246345 A1 HK 1246345A1 HK 18105611 A HK18105611 A HK 18105611A HK 1246345 A1 HK1246345 A1 HK 1246345A1
Authority
HK
Hong Kong
Prior art keywords
culturing
methods
mammalian cell
mammalian
cell
Prior art date
Application number
HK18105611.8A
Other languages
English (en)
Inventor
Christopher Hwang
Timothy Johnson
Jason Walther
Cheng Cheng
Jonathan Wang
Neha Shah
Seul-A Bae
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of HK1246345A1 publication Critical patent/HK1246345A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0681—Cells of the genital tract; Non-germinal cells from gonads
    • C12N5/0682—Cells of the female genital tract, e.g. endometrium; Non-germinal cells from ovaries, e.g. ovarian follicle cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/0043—Medium free of human- or animal-derived components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/005—Protein-free medium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2465—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1) acting on alpha-galactose-glycoside bonds, e.g. alpha-galactosidase (3.2.1.22)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/50—Soluble polymers, e.g. polyethyleneglycol [PEG]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01022—Alpha-galactosidase (3.2.1.22)
HK18105611.8A 2014-12-22 2018-04-30 培養哺乳動物細胞的方法 HK1246345A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462095734P 2014-12-22 2014-12-22
PCT/US2015/067040 WO2016106192A2 (en) 2014-12-22 2015-12-21 Methods of culturing a mammalian cell

Publications (1)

Publication Number Publication Date
HK1246345A1 true HK1246345A1 (zh) 2018-09-07

Family

ID=55527619

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18105611.8A HK1246345A1 (zh) 2014-12-22 2018-04-30 培養哺乳動物細胞的方法

Country Status (15)

Country Link
US (2) US11306341B2 (zh)
EP (1) EP3237604A2 (zh)
JP (4) JP6843750B2 (zh)
KR (2) KR102568951B1 (zh)
CN (1) CN107567495A (zh)
AU (2) AU2015369809B2 (zh)
BR (1) BR112017013423B1 (zh)
CA (2) CA2971861C (zh)
HK (1) HK1246345A1 (zh)
IL (2) IL253071B2 (zh)
MX (2) MX2017008338A (zh)
RU (1) RU2712746C2 (zh)
SG (2) SG11201705103WA (zh)
TW (3) TWI751103B (zh)
WO (1) WO2016106192A2 (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201506343QA (en) 2013-02-22 2015-09-29 Genzyme Corp Microcarrier perfusion culturing methods and uses thereof
ES2717927T3 (es) 2013-02-22 2019-06-26 Genzyme Corp Procedimientos de cultivo por perfusión de microportadores y usos de los mismos
TW202204596A (zh) 2014-06-06 2022-02-01 美商健臻公司 灌注培養方法及其用途
TWI776235B (zh) 2014-06-09 2022-09-01 美商健臻公司 種子罐培養法(seed train processes)及其用途
BR112017013423B1 (pt) 2014-12-22 2023-04-11 Genzyme Corporation Métodos para cultivo de célula de mamífero
US11391725B2 (en) * 2018-03-16 2022-07-19 Genzyme Corporation Methods for improving cell viability in a production bioreactor
EP4196769A1 (en) * 2020-08-12 2023-06-21 Allen Institute Systems, devices, and methods for quality control of cell production using predictive tagging
CN112795531B (zh) * 2021-04-11 2021-08-06 依科赛生物科技（太仓）有限公司 一种cho细胞无血清无蛋白培养基及其用途

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
US6458574B1 (en) * 1996-09-12 2002-10-01 Transkaryotic Therapies, Inc. Treatment of a α-galactosidase a deficiency
AU2002232726A1 (en) 2000-12-20 2002-07-01 Bayer Pharmaceuticals Corporation A device and method for seed-train expansion of mammalian cells
AU2002348151A1 (en) 2001-11-05 2003-05-19 Genvec, Inc. Viral vector production methods and compositions
US6953692B2 (en) 2001-12-18 2005-10-11 Bayer Pharmaceuticals Corporation Device and method for seed-train expansion of mammalian cells
US6974681B1 (en) 2002-08-23 2005-12-13 Immunex Corporation Cell culture performance with vanadate
US7067279B1 (en) 2002-08-23 2006-06-27 Immunex Corporation Cell culture performance with betaine
US20050186669A1 (en) 2004-02-20 2005-08-25 Cesco Bioengineering Co., Ltd. Apparatus and method for preparing and culturing cells
AU2005287162B2 (en) 2004-09-16 2010-12-23 Becton, Dickinson And Company Perfusion bioreactor for culturing cells
EP1891205B1 (en) 2005-06-15 2017-12-27 Zhejiang Jinyishengshi Bioengineering Co., Ltd. Suspension culture vessels
WO2006138143A1 (en) 2005-06-15 2006-12-28 Amprotein Corporation Suspension culture vessels
WO2008024769A2 (en) * 2006-08-21 2008-02-28 Raven Biotechnologies, Inc. Intensified perfusion production method
WO2008106515A1 (en) 2007-02-27 2008-09-04 The Board Of Trustees Of The University Of Illinois Insert device for multiwell plate
WO2009034186A2 (en) 2007-09-13 2009-03-19 Helmholtz-Zentrum für Infektionsforschung GmbH Process for cell cultivation
DK2205244T3 (da) * 2007-11-08 2013-11-25 Ambit Biosciences Corp Fremgangsmåder til indgivelse af n-(5-tert-butyl-isoxazol-3-yl)-n'-{4-[7-(2-morpholin-4-yl-ethoxy-)imidazo-[2,1-b]-[1,3]-benzothiazol-2-yl]-phenyl}urinstof til behandling af proliferativ sygdom
JP5806465B2 (ja) * 2007-12-31 2015-11-10 バクスター・インターナショナル・インコーポレイテッドＢａｘｔｅｒ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｉｎｃｏｒｐ０Ｒａｔｅｄ 実質的に動物性タンパク質を含まない組換えフリンおよび実質的に動物性タンパク質を含まない組換えフリンを作製するための方法
US20090233334A1 (en) * 2008-03-11 2009-09-17 Excellgene Sa Cell cultivation and production of recombinant proteins by means of an orbital shake bioreactor system with disposable bags at the 1,500 liter scale
DE102008019691A1 (de) 2008-04-15 2009-10-29 Technische Universität Ilmenau Teilaktives mikrofluidisches System für die 3D-Zellkultivierung sowie Verfahren zu dessen Perfusion
WO2010120514A2 (en) 2009-03-31 2010-10-21 The Trustees Of The University Of Pennsylvania Antigen-binding proteins comprising recombinant protein scaffolds
EP3255153A1 (en) * 2009-11-17 2017-12-13 E. R. Squibb & Sons, L.L.C. Methods for enhanced protein production
AU2012252305B2 (en) 2011-05-12 2017-02-02 Probiogen Ag Enhancement of protein production yield mediated by a fast shuttling cdc42 gtpase
WO2013116449A1 (en) 2012-02-02 2013-08-08 Corning Incorporated Automatic continuous perfusion cell culture microplate consumables
CN106399094A (zh) 2012-04-01 2017-02-15 Emd密理博公司 细胞培养和梯度迁移化验方法和装置
US20140154726A1 (en) 2012-10-23 2014-06-05 Genzyme Corporation Perfusion Culturing Methods and Uses Thereof
SG11201506343QA (en) 2013-02-22 2015-09-29 Genzyme Corp Microcarrier perfusion culturing methods and uses thereof
ES2717927T3 (es) 2013-02-22 2019-06-26 Genzyme Corp Procedimientos de cultivo por perfusión de microportadores y usos de los mismos
MX2015012114A (es) 2013-03-08 2016-01-12 Genzyme Corp Fabricacion continua integrada de principios activos proteinicos terapeuticos.
WO2014151901A1 (en) 2013-03-14 2014-09-25 Abbvie Inc. Improvement of mammalian cell culture performance through surfactant supplementation of feed media
TWI656839B (zh) 2013-03-15 2019-04-21 健臻公司 高密度細胞儲存方法
US20160131634A1 (en) 2013-05-29 2016-05-12 Biogen Ma Inc. Methods of evaluating cell culture additives
AU2014318420B2 (en) 2013-09-16 2020-01-16 Genzyme Corporation Methods and systems for processing a cell culture
TWI709569B (zh) 2014-01-17 2020-11-11 美商健臻公司 無菌層析樹脂及其用於製造方法的用途
TWI709570B (zh) 2014-01-17 2020-11-11 美商健臻公司 無菌層析法及製法
SG11201610143VA (en) * 2014-06-04 2017-01-27 Amgen Inc Methods for harvesting mammalian cell cultures
TW202204596A (zh) 2014-06-06 2022-02-01 美商健臻公司 灌注培養方法及其用途
TWI776235B (zh) 2014-06-09 2022-09-01 美商健臻公司 種子罐培養法(seed train processes)及其用途
BR112017013423B1 (pt) 2014-12-22 2023-04-11 Genzyme Corporation Métodos para cultivo de célula de mamífero

Also Published As

Publication number Publication date
IL253071B1 (en) 2023-12-01
IL308064A (en) 2023-12-01
TWI751103B (zh) 2022-01-01
CN107567495A (zh) 2018-01-09
EP3237604A2 (en) 2017-11-01
KR20230125102A (ko) 2023-08-28
CA2971861C (en) 2024-02-13
WO2016106192A3 (en) 2016-11-03
TWI741851B (zh) 2021-10-01
JP2022107000A (ja) 2022-07-20
BR112017013423A2 (pt) 2018-01-09
MX2021007433A (es) 2021-08-05
IL253071A0 (en) 2017-08-31
JP6843750B2 (ja) 2021-03-17
KR20170090508A (ko) 2017-08-07
JP7075463B2 (ja) 2022-05-25
AU2015369809A1 (en) 2017-08-10
JP2021019624A (ja) 2021-02-18
US11306341B2 (en) 2022-04-19
CA2971861A1 (en) 2016-06-30
KR102568951B1 (ko) 2023-08-22
RU2020101112A (ru) 2020-03-13
MX2017008338A (es) 2017-10-19
JP2017538435A (ja) 2017-12-28
AU2022204152A1 (en) 2022-06-30
SG11201705103WA (en) 2017-07-28
IL253071B2 (en) 2024-04-01
BR112017013423B1 (pt) 2023-04-11
RU2017126045A (ru) 2019-01-24
TW201639881A (zh) 2016-11-16
CA3225136A1 (en) 2016-06-30
US20160177361A1 (en) 2016-06-23
US20220145348A1 (en) 2022-05-12
TW202106706A (zh) 2021-02-16
RU2017126045A3 (zh) 2019-06-24
SG10202001034PA (en) 2020-04-29
WO2016106192A2 (en) 2016-06-30
AU2015369809B2 (en) 2022-03-17
RU2712746C2 (ru) 2020-01-30
JP2024050754A (ja) 2024-04-10
TW202200785A (zh) 2022-01-01

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