JP6831337B2 - 質量スペクトルデータを処理する技術 - Google Patents

質量スペクトルデータを処理する技術 Download PDF

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JP6831337B2
JP6831337B2 JP2017561835A JP2017561835A JP6831337B2 JP 6831337 B2 JP6831337 B2 JP 6831337B2 JP 2017561835 A JP2017561835 A JP 2017561835A JP 2017561835 A JP2017561835 A JP 2017561835A JP 6831337 B2 JP6831337 B2 JP 6831337B2
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ゲロマノス，スコット・ジェイ
チャバリーニ，スティーブン・ジェイ
デブリン，クルト
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ウオーターズ・テクノロジーズ・コーポレイシヨン
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    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
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    • G01N30/86—Signal analysis
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
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    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
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    • G—PHYSICS
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    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
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    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
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    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
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    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
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    • H01J49/0036—Step by step routines describing the handling of the data generated during a measurement

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JP2017561835A 2015-05-29 2016-05-31 質量スペクトルデータを処理する技術 Expired - Fee Related JP6831337B2 (ja)

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US201562168123P 2015-05-29 2015-05-29
US62/168,123 2015-05-29
PCT/US2016/034959 WO2016196432A1 (en) 2015-05-29 2016-05-31 Techniques for processing of mass spectral data

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JP2018517905A JP2018517905A (ja) 2018-07-05
JP2018517905A5 JP2018517905A5 (enExample) 2019-07-04
JP6831337B2 true JP6831337B2 (ja) 2021-02-17

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EP (1) EP3304382B1 (enExample)
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KR (1) KR20180033466A (enExample)
CN (1) CN108140060B (enExample)
WO (1) WO2016196432A1 (enExample)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6698668B2 (ja) * 2015-02-05 2020-05-27 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド 断片化エネルギーを切り替えながらの幅広い四重極ｒｆ窓の高速スキャニング
JP6831337B2 (ja) * 2015-05-29 2021-02-17 ウオーターズ・テクノロジーズ・コーポレイシヨン 質量スペクトルデータを処理する技術
GB2544959B (en) * 2015-09-17 2019-06-05 Thermo Fisher Scient Bremen Gmbh Mass spectrometer
EP4328583A3 (en) * 2016-04-08 2024-05-01 Shimadzu Corporation Chromatograph mass spectrometer
EP3285190B1 (en) * 2016-05-23 2025-07-23 Thermo Finnigan LLC Systems and methods for sample comparison and classification
US10909177B1 (en) * 2017-01-17 2021-02-02 Workday, Inc. Percentile determination system
CN110692118A (zh) * 2017-06-01 2020-01-14 萨默费尼根有限公司 质谱仪碰撞能量的自动测定
US20190034047A1 (en) * 2017-07-31 2019-01-31 Wisconsin Alumni Research Foundation Web-Based Data Upload and Visualization Platform Enabling Creation of Code-Free Exploration of MS-Based Omics Data
DE102017008885B4 (de) * 2017-09-22 2024-04-25 Bruker Daltonics GmbH & Co. KG Massenspektrometrisches Verfahren und MALDI-TOF-Massenspektrometer
JP7105049B2 (ja) * 2017-10-02 2022-07-22 日本電子株式会社 質量分析データ処理装置、及び質量分析データ処理方法
US10878944B2 (en) * 2018-03-23 2020-12-29 Thermo Finnigan Llc Methods for combining predicted and observed mass spectral fragmentation data
WO2019232520A1 (en) 2018-06-01 2019-12-05 Cerno Bioscience Llc Mass spectral analysis of large molecules
US11573201B2 (en) 2018-06-15 2023-02-07 Okinawa Institute Of Science And Technology School Corporation Method and system for identifying structure of compound
EP3884270A1 (en) * 2018-11-21 2021-09-29 Waters Technologies Ireland Limited Techniques for evaluating analytical instrument performance
CN109543324B (zh) * 2018-11-28 2022-09-13 哈尔滨工业大学 基于皮尔逊相关系数的热机械分析曲线转折点的测定方法
US11913922B2 (en) * 2019-03-15 2024-02-27 Waters Technologies Ireland Limited Techniques for targeted compound analysis
US11887700B2 (en) * 2019-05-03 2024-01-30 Waters Technologies Ireland Limited Techniques for generating encoded representations of compounds
TWI723867B (zh) * 2019-05-10 2021-04-01 中央研究院 用以產生高解析度圖譜的動態數據校正方法及裝置
GB2584125B (en) * 2019-05-22 2021-11-03 Thermo Fisher Scient Bremen Gmbh Dynamic control of accumulation time for chromatography mass spectrometry
WO2020240506A1 (en) * 2019-05-31 2020-12-03 Dh Technologies Development Pte. Ltd. Method for real time encoding of scanning swath data and probabilistic framework for precursor inference
US12002670B2 (en) * 2019-07-04 2024-06-04 Shimadzu Corporation Chromatograph mass spectrometer
JP7583812B2 (ja) * 2019-12-17 2024-11-14 エフ． ホフマン－ラ ロシュ アーゲー 複数の反復ハードウェア構成要素を有する少なくとも１つの分析装置を較正するための方法
CN112305400B (zh) * 2020-01-04 2023-09-29 成都华微电子科技股份有限公司 一种参数快速扫描测试装置和方法
CA3166241A1 (en) * 2020-01-31 2021-08-05 Jikang WU High confidence compound identification by liquid chromatography-mass spectrometry
CN111370072B (zh) * 2020-03-04 2020-11-17 西湖大学 基于数据非依赖采集质谱的分子组学数据结构的实现方法
JP7375640B2 (ja) * 2020-03-23 2023-11-08 株式会社島津製作所 イメージング質量分析システム、及び、イメージング質量分析を利用した分析方法
CN111351876A (zh) * 2020-04-01 2020-06-30 上海中科新生命生物科技有限公司 一种抗体药中宿主细胞蛋白半绝对定量检测方法
CN111418383B (zh) * 2020-04-16 2021-08-24 桂林理工大学 基于根系发育参数的污染暴露下化学调控剂的筛选方法
WO2021214728A1 (en) * 2020-04-24 2021-10-28 Waters Technologies Ireland Limited Methods, mediums, and systems to compare data within and between cohorts
CN111398402B (zh) * 2020-04-29 2022-09-27 中国计量科学研究院 基于线性离子阱梯度隔离策略的离子构象分布表征方法
GB202012094D0 (en) * 2020-08-04 2020-09-16 Micromass Ltd Ion identification using ion mobility spectrometry
JP7667250B2 (ja) * 2020-08-06 2025-04-22 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド 質量分析法における荷電状態割り当てのためのシステムおよび方法
CN111830184B (zh) * 2020-08-07 2021-06-22 中国农业科学院农业质量标准与检测技术研究所 一种鉴别氯吡脲施用后薄皮甜瓜果实质量差异的方法
JP7580577B2 (ja) * 2020-08-14 2024-11-11 メタボロン，インコーポレイテッド 複雑な混合物の小分子成分を決定するための方法並びに関連する装置及びコンピュータプログラム製品
US11587774B2 (en) * 2020-09-21 2023-02-21 Thermo Finnigan Llc Using real time search results to dynamically exclude product ions that may be present in the master scan
CN116324403A (zh) * 2020-10-30 2023-06-23 Dh科技发展私人贸易有限公司 通过质谱法进行的化合物识别
CN112634997B (zh) * 2020-11-16 2024-09-06 中国科学院上海有机化学研究所 一种甾醇数据库建立及甾醇分析方法
US11721538B2 (en) * 2020-11-17 2023-08-08 Thermo Finnigan Llc Feeding real time search results of chimeric MS2 spectra into the dynamic exclusion list
KR102518410B1 (ko) * 2021-02-03 2023-04-06 한국과학기술연구원 기체크로마토그래피의 ucm 정보를 이용한 유종분석방법 및 장치
EP4047371A1 (en) * 2021-02-18 2022-08-24 Thermo Fisher Scientific (Bremen) GmbH Method and apparatus for analysing samples of biomolecules using mass spectrometry with data-independent acquisition
WO2023084770A1 (ja) 2021-11-15 2023-05-19 日本たばこ産業株式会社 非燃焼加熱型スティック
EP4181169A1 (en) * 2021-11-15 2023-05-17 Thermo Fisher Scientific (Bremen) GmbH Mass spectrometer isolation profile analyser
CN114091627B (zh) * 2022-01-20 2022-03-25 华谱科仪(北京)科技有限公司 色谱仪试验数据验证方法、装置、存储介质及电子设备
WO2023193172A1 (en) * 2022-04-07 2023-10-12 Aspentech Corporation Automated, configurable, rigorous reversible lumping for chemical separations
KR20250002633A (ko) * 2022-04-27 2025-01-07 엘리멘탈 사이언티픽, 인코포레이티드 국소적 최소 분석을 통한 나노입자 검출 역치 결정
US11908670B2 (en) 2022-05-16 2024-02-20 Thermo Finnigan Llc Systems and methods of ion population regulation in mass spectrometry
WO2023233327A1 (en) * 2022-05-31 2023-12-07 Waters Technologies Ireland Limited Methods, mediums, and systems for targeted isotope clustering
WO2024026114A1 (en) * 2022-07-29 2024-02-01 The General Hospital Corporation High-throughput proteome mapping
GB2621393B (en) * 2022-08-12 2024-12-25 Thermo Fisher Scient Bremen Gmbh Methods and mass spectrometry systems for acquiring mass spectral data
CN115130788B (zh) * 2022-08-29 2022-11-22 江苏濠玥电子科技有限公司 基于大数据分析的用电预测系统
JP2024070693A (ja) * 2022-11-11 2024-05-23 トヨタ自動車株式会社 情報処理装置、情報処理方法、及び情報処理プログラム
WO2024133265A1 (en) * 2022-12-19 2024-06-27 Ares Trading S.A. Method for determining peak characteristics on analytical data sets
EP4390390A1 (en) * 2022-12-19 2024-06-26 Ares Trading S.A. Method for determining peak characteristics on analytical data sets
US12085497B1 (en) 2023-04-12 2024-09-10 Elemental Scientific, Inc. Nanoparticle analysis for ultra-low level concentrations of nanoparticles in fluid samples
CN116106396B (zh) * 2023-04-13 2023-06-27 杭州汇健科技有限公司 质谱数据的全谱拟合动态校正方法、装置、介质及质谱仪
US20240402201A1 (en) * 2023-06-01 2024-12-05 Thermo Finnigan Llc Acquisition scheduling and load balancing for targeted mass spectrometry
CN117330690B (zh) * 2023-08-21 2025-10-03 国科大杭州高等研究院 一种数据非依赖性采集质谱特征碎片的非靶标分析方法
CN117334257A (zh) * 2023-09-15 2024-01-02 浙江寿仙谷植物药研究院有限公司 一种灵芝多层级筛查质谱数据库及其建立方法和应用
CN117524385B (zh) * 2024-01-04 2024-04-16 西瑞思创(西安)实验仪器有限公司 一种高通量全自动材料快速评价分析软件数据处理方法
CN118067827B (zh) * 2024-04-22 2024-08-06 清谱科技(苏州)有限公司 一种用于idh基因突变标志物检测的质谱系统及提高检测准确性的方法

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2340150C (en) 2000-06-09 2005-11-22 Micromass Limited Methods and apparatus for mass spectrometry
TWI314212B (en) * 2000-12-14 2009-09-01 Stroobant Paul Differential phage capture proteomics
ATE327512T1 (de) * 2001-12-08 2006-06-15 Micromass Ltd Massenspektrometrie-verfahren
GB2408574B (en) 2001-12-08 2006-01-04 Micromass Ltd Method of mass spectrometry
JP4449064B2 (ja) * 2003-01-27 2010-04-14 ティーイーエル エピオン インク． ガスクラスタ・イオン・ビームを測定しかつ制御する方法とそのための装置
US7684934B2 (en) * 2003-06-06 2010-03-23 The United States Of America As Represented By The Department Of Health And Human Services Pattern recognition of whole cell mass spectra
US7197402B2 (en) * 2004-10-14 2007-03-27 Highchem, Ltd. Determination of molecular structures using tandem mass spectrometry
WO2006133191A2 (en) * 2005-06-03 2006-12-14 Waters Investments Limited Methods and apparatus for performing retention-time matching
CA2656565A1 (en) * 2006-06-29 2008-08-07 Ionwerks, Inc. Neutral/ion reactor in adiabatic supersonic gas flow for ion mobility time-of-flight mass spectrometry
GB2471155B (en) 2009-05-06 2016-04-20 Agilent Technologies Inc Data dependent acquisition system for mass spectrometery and methods of use
JP5375411B2 (ja) * 2009-07-29 2013-12-25 株式会社島津製作所 クロマトグラフ質量分析データ解析方法及び装置
CN102169791B (zh) * 2010-02-05 2015-11-25 岛津分析技术研发（上海）有限公司 一种串级质谱分析装置及质谱分析方法
JP5441064B2 (ja) * 2010-09-07 2014-03-12 独立行政法人科学技術振興機構 物質の構造解析方法
CN106055895B (zh) * 2010-09-15 2021-02-19 Dh科技发展私人贸易有限公司 产物离子谱的数据独立获取及参考谱库匹配
CN102445544B (zh) * 2010-10-15 2013-10-30 中国科学院计算技术研究所 一种提高单同位素峰判断准确率的方法和系统
JP5408107B2 (ja) * 2010-11-10 2014-02-05 株式会社島津製作所 Ｍｓ／ｍｓ型質量分析装置及び同装置用プログラム
DE102010054580B3 (de) * 2010-12-15 2012-04-26 Bruker Daltonik Gmbh Proteomanalyse in Massenspektrometern mit HF-Ionenfallen
US8536518B2 (en) 2011-06-27 2013-09-17 U.S. Department of Homeland Security Ion mobility spectrometer to mass spectrometer interface
JP5840915B2 (ja) * 2011-10-27 2016-01-06 株式会社日立製作所 糖ペプチドイオンを効率的に選択可能な質量分析方法及び装置
WO2013098618A1 (en) * 2011-12-29 2013-07-04 Dh Technologies Development Pte. Ltd. Use of windowed mass spectrometry data for retention time determination or confirmation
JP5757270B2 (ja) * 2012-04-26 2015-07-29 株式会社島津製作所 クロマトグラフ質量分析用データ処理装置
CN102788720B (zh) * 2012-06-05 2016-01-06 西北大学 一种滤膜辅助分离生物样本中糖蛋白全n-连接糖链及其鉴别方法
EP3155638B1 (en) * 2014-06-13 2023-09-20 Waters Technologies Corporation Analysis of complex biological matrices through targeting and advanced precursor and product ion alignment
JP6698668B2 (ja) * 2015-02-05 2020-05-27 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド 断片化エネルギーを切り替えながらの幅広い四重極ｒｆ窓の高速スキャニング
JP6831337B2 (ja) * 2015-05-29 2021-02-17 ウオーターズ・テクノロジーズ・コーポレイシヨン 質量スペクトルデータを処理する技術

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