JP6771464B2 - Ｃｂｐおよび／またはｅｐ３００インヒビターとしての、４，５，６，７−テトラヒドロ−１ｈ−ピラゾロ［４，３−ｃ］ピリジン−３−アミン化合物 - Google Patents
Ｃｂｐおよび／またはｅｐ３００インヒビターとしての、４，５，６，７−テトラヒドロ−１ｈ−ピラゾロ［４，３−ｃ］ピリジン−３−アミン化合物 Download PDFInfo
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- JP6771464B2 JP6771464B2 JP2017528520A JP2017528520A JP6771464B2 JP 6771464 B2 JP6771464 B2 JP 6771464B2 JP 2017528520 A JP2017528520 A JP 2017528520A JP 2017528520 A JP2017528520 A JP 2017528520A JP 6771464 B2 JP6771464 B2 JP 6771464B2
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
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| CNPCT/CN2014/092380 | 2014-11-27 | ||
| CN2014092380 | 2014-11-27 | ||
| CNPCT/CN2015/092965 | 2015-10-27 | ||
| CN2015092965 | 2015-10-27 | ||
| PCT/US2015/062794 WO2016086200A1 (en) | 2014-11-27 | 2015-11-25 | 4,5,6,7-tetrahydro-1 h-pyrazolo[4,3-c]pyridin-3-amine compounds as cbp and/or ep300 inhibitors |
Publications (3)
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| JP2017537100A JP2017537100A (ja) | 2017-12-14 |
| JP2017537100A5 JP2017537100A5 (cg-RX-API-DMAC7.html) | 2019-01-10 |
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| JP2017528520A Active JP6771464B2 (ja) | 2014-11-27 | 2015-11-25 | Ｃｂｐおよび／またはｅｐ３００インヒビターとしての、４，５，６，７−テトラヒドロ−１ｈ−ピラゾロ［４，３−ｃ］ピリジン−３−アミン化合物 |
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| WO (1) | WO2016086200A1 (cg-RX-API-DMAC7.html) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2019516759A (ja) * | 2016-05-24 | 2019-06-20 | ジェネンテック， インコーポレイテッド | がんの処置のためのピラゾロピリジン誘導体 |
| JP2024517496A (ja) * | 2021-05-14 | 2024-04-22 | 武漢朗来科技発展有限公司 | Ｒｏｃｋ阻害剤の酸付加塩及び塩の結晶形、組成物並びに薬物用途 |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MA40940A (fr) * | 2014-11-10 | 2017-09-19 | Constellation Pharmaceuticals Inc | Pyrrolopyridines substituées utilisées en tant qu'inhibiteurs de bromodomaines |
| JP6639497B2 (ja) | 2014-11-10 | 2020-02-05 | ジェネンテック， インコーポレイテッド | ブロモドメインインヒビターおよびその使用 |
| MA40943A (fr) | 2014-11-10 | 2017-09-19 | Constellation Pharmaceuticals Inc | Pyrrolopyridines substituées utilisées en tant qu'inhibiteurs de bromodomaines |
| KR20170101913A (ko) * | 2014-12-05 | 2017-09-06 | 에이치 리 모피트 캔서 센터 앤드 리서어치 인스티튜트 아이엔씨 | 암 면역치료의 보조제로서의 브로모도메인 억제제 |
| CN107531692B (zh) | 2015-01-29 | 2020-12-25 | 基因泰克公司 | 治疗化合物及其用途 |
| AR104259A1 (es) | 2015-04-15 | 2017-07-05 | Celgene Quanticel Res Inc | Inhibidores de bromodominio |
| CN115028617A (zh) * | 2016-05-24 | 2022-09-09 | 基因泰克公司 | Cbp/ep300的杂环抑制剂及其在治疗癌症中的用途 |
| US20190270797A1 (en) | 2016-07-25 | 2019-09-05 | Epizyme, Inc. | Crebbp related cancer therapy |
| GB201617630D0 (en) * | 2016-10-18 | 2016-11-30 | Cellcentric Ltd | Pharmaceutical compounds |
| GB201617627D0 (en) * | 2016-10-18 | 2016-11-30 | Cellcentric Ltd | Pharmaceutical compounds |
| US11040027B2 (en) | 2017-01-17 | 2021-06-22 | Heparegenix Gmbh | Protein kinase inhibitors for promoting liver regeneration or reducing or preventing hepatocyte death |
| EP3643703A4 (en) * | 2017-06-21 | 2020-12-23 | Daiichi Sankyo Co., Ltd. | EP300 / CREBBP INHIBITOR |
| CA3075880A1 (en) | 2017-09-15 | 2019-03-21 | Forma Therapeutics, Inc. | Tetrahydro-imidazo quinoline compositions as cbp/p300 inhibitors |
| BR112020008765A2 (pt) | 2017-11-02 | 2020-10-20 | Aicuris Gmbh & Co. Kg | indol-2-carboxamidas pirazolo-piperidina substituídas altamente ativas inovadoras ativas contra o vírus da hepatite b (hbv) |
| WO2019191667A1 (en) * | 2018-03-29 | 2019-10-03 | Board Of Regents, The University Of Texas System | Imidazopiperazine inhibitors of transcription activating proteins |
| WO2019195846A1 (en) | 2018-04-06 | 2019-10-10 | Board Of Regents, The University Of Texas System | Imidazopiperazinone inhibitors of transcription activating proteins |
| GB201806320D0 (en) | 2018-04-18 | 2018-05-30 | Cellcentric Ltd | Process |
| GB201809295D0 (en) | 2018-06-06 | 2018-07-25 | Institute Of Cancer Res Royal Cancer Hospital | Lox inhibitors |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2019516759A (ja) * | 2016-05-24 | 2019-06-20 | ジェネンテック， インコーポレイテッド | がんの処置のためのピラゾロピリジン誘導体 |
| JP7014736B2 (ja) | 2016-05-24 | 2022-02-01 | ジェネンテック， インコーポレイテッド | がんの処置のためのピラゾロピリジン誘導体 |
| JP2024517496A (ja) * | 2021-05-14 | 2024-04-22 | 武漢朗来科技発展有限公司 | Ｒｏｃｋ阻害剤の酸付加塩及び塩の結晶形、組成物並びに薬物用途 |
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| EP3224258B1 (en) | 2019-08-14 |
| WO2016086200A1 (en) | 2016-06-02 |
| HK1248695A1 (zh) | 2018-10-19 |
| CN107531690B (zh) | 2020-11-06 |
| WO2016086200A9 (en) | 2016-06-23 |
| CN107531690A (zh) | 2018-01-02 |
| US20160158207A1 (en) | 2016-06-09 |
| US20170333406A1 (en) | 2017-11-23 |
| US9763922B2 (en) | 2017-09-19 |
| EP3224258A1 (en) | 2017-10-04 |
| EP3632915A1 (en) | 2020-04-08 |
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