JP6672140B2 - Ｇｌｐ−１化合物の経口投薬 - Google Patents

Ｇｌｐ−１化合物の経口投薬 Download PDF

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Publication number
JP6672140B2
JP6672140B2 JP2016511088A JP2016511088A JP6672140B2 JP 6672140 B2 JP6672140 B2 JP 6672140B2 JP 2016511088 A JP2016511088 A JP 2016511088A JP 2016511088 A JP2016511088 A JP 2016511088A JP 6672140 B2 JP6672140 B2 JP 6672140B2
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peptide
composition
glp
ethoxy
administered
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JP2016519128A5 (enExample
JP2016519128A (ja
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フレミング・セイエル・ニールセン
ペル・サウエルバリ
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Novo Nordisk AS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2016511088A 2013-05-02 2014-05-02 Ｇｌｐ−１化合物の経口投薬 Active JP6672140B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2019235054A JP7576910B2 (ja) 2013-05-02 2019-12-25 Ｇｌｐ－１化合物の経口投薬

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13166205.8 2013-05-02
EP13166205 2013-05-02
PCT/EP2014/058974 WO2014177683A1 (en) 2013-05-02 2014-05-02 Oral dosing of glp-1 compounds

Related Child Applications (1)

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JP2019235054A Division JP7576910B2 (ja) 2013-05-02 2019-12-25 Ｇｌｐ－１化合物の経口投薬

Publications (3)

Publication Number Publication Date
JP2016519128A JP2016519128A (ja) 2016-06-30
JP2016519128A5 JP2016519128A5 (enExample) 2017-06-15
JP6672140B2 true JP6672140B2 (ja) 2020-03-25

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JP2016511088A Active JP6672140B2 (ja) 2013-05-02 2014-05-02 Ｇｌｐ−１化合物の経口投薬
JP2019235054A Active JP7576910B2 (ja) 2013-05-02 2019-12-25 Ｇｌｐ－１化合物の経口投薬

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Country Status (25)

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US (6) US20160067184A1 (enExample)
EP (2) EP2991671B1 (enExample)
JP (2) JP6672140B2 (enExample)
KR (3) KR20210086717A (enExample)
AU (1) AU2014261336B2 (enExample)
BR (1) BR112015026325A2 (enExample)
CA (1) CA2910903A1 (enExample)
CY (1) CY1120730T1 (enExample)
DK (1) DK2991671T3 (enExample)
ES (1) ES2688462T3 (enExample)
HR (1) HRP20181393T1 (enExample)
HU (1) HUE040609T2 (enExample)
IL (1) IL241813A (enExample)
LT (1) LT2991671T (enExample)
MX (3) MX369259B (enExample)
MY (1) MY172578A (enExample)
PL (1) PL2991671T3 (enExample)
PT (1) PT2991671T (enExample)
RS (1) RS58039B1 (enExample)
RU (1) RU2671406C2 (enExample)
SA (1) SA515370075B1 (enExample)
SI (1) SI2991671T1 (enExample)
SM (1) SMT201800492T1 (enExample)
WO (1) WO2014177683A1 (enExample)
ZA (2) ZA201507096B (enExample)

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