JP6642935B2 - 眼投与用の半フッ素化化合物 - Google Patents

眼投与用の半フッ素化化合物 Download PDF

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Publication number
JP6642935B2
JP6642935B2 JP2018515471A JP2018515471A JP6642935B2 JP 6642935 B2 JP6642935 B2 JP 6642935B2 JP 2018515471 A JP2018515471 A JP 2018515471A JP 2018515471 A JP2018515471 A JP 2018515471A JP 6642935 B2 JP6642935 B2 JP 6642935B2
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composition
compound
symptoms
composition according
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JP2018529693A (ja
JP2018529693A5 (enExample
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シェラー，ディーター
グリレンベルガー，ラルフ
レッシャー，フランク
フォス，ハルトムート
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ノバリック ゲーエムベーハー
ノバリック ゲーエムベーハー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/02—Halogenated hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
    • C07C17/263—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
    • C07C17/266—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions of hydrocarbons and halogenated hydrocarbons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C19/00—Acyclic saturated compounds containing halogen atoms
    • C07C19/08—Acyclic saturated compounds containing halogen atoms containing fluorine

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
JP2018515471A 2015-09-30 2016-09-29 眼投与用の半フッ素化化合物 Active JP6642935B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP15187760.2 2015-09-30
EP15187760 2015-09-30
EP15192429.7 2015-10-30
EP15192429 2015-10-30
PCT/EP2016/073262 WO2017055453A1 (en) 2015-09-30 2016-09-29 Semifluorinated compounds for ophthalmic administration

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019240070A Division JP7050741B2 (ja) 2015-09-30 2019-12-30 眼投与用の半フッ素化化合物

Publications (3)

Publication Number Publication Date
JP2018529693A JP2018529693A (ja) 2018-10-11
JP2018529693A5 JP2018529693A5 (enExample) 2019-12-19
JP6642935B2 true JP6642935B2 (ja) 2020-02-12

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JP2018515471A Active JP6642935B2 (ja) 2015-09-30 2016-09-29 眼投与用の半フッ素化化合物
JP2019240070A Active JP7050741B2 (ja) 2015-09-30 2019-12-30 眼投与用の半フッ素化化合物

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JP2019240070A Active JP7050741B2 (ja) 2015-09-30 2019-12-30 眼投与用の半フッ素化化合物

Country Status (14)

Country Link
US (2) US11154513B2 (enExample)
EP (3) EP3722274B1 (enExample)
JP (2) JP6642935B2 (enExample)
KR (2) KR102584063B1 (enExample)
CN (3) CN108349855B (enExample)
AU (3) AU2016329261B2 (enExample)
CA (1) CA2998269C (enExample)
DE (1) DE202016008739U1 (enExample)
DK (2) DK3356313T3 (enExample)
ES (2) ES2953837T3 (enExample)
MX (2) MX391587B (enExample)
PL (2) PL3722274T3 (enExample)
PT (1) PT3356313T (enExample)
WO (1) WO2017055453A1 (enExample)

Cited By (1)

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JP2020073551A (ja) * 2015-09-30 2020-05-14 ノバリック ゲーエムベーハー 眼投与用の半フッ素化化合物

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EP2462921A1 (en) 2010-11-11 2012-06-13 Novaliq GmbH Liquid pharmaceutical compositions for the treatment of a posterior eye disease
JP6039145B2 (ja) 2011-05-25 2016-12-07 ノバリック ゲーエムベーハー 半フッ化アルカンを基礎にした局所薬学的組成物
CN104066442B (zh) 2012-01-23 2018-05-18 诺瓦利克有限责任公司 基于半氟化烷烃的稳定蛋白质组合物
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DK3399962T3 (da) * 2016-12-23 2020-09-07 Novaliq Gmbh Oftalmisk sammensætning til behandling af tør øjensygdom
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JP2021522219A (ja) 2018-04-27 2021-08-30 ノバリック ゲーエムベーハー 緑内障の治療のためのタフルプロストを含む眼科用組成物
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