MX353154B - Emulsiones de aceite/agua que comprenden alcanos semifluorados. - Google Patents
Emulsiones de aceite/agua que comprenden alcanos semifluorados.Info
- Publication number
- MX353154B MX353154B MX2013007807A MX2013007807A MX353154B MX 353154 B MX353154 B MX 353154B MX 2013007807 A MX2013007807 A MX 2013007807A MX 2013007807 A MX2013007807 A MX 2013007807A MX 353154 B MX353154 B MX 353154B
- Authority
- MX
- Mexico
- Prior art keywords
- emulsions
- semi
- fluorinated alkane
- semifluorinated alkanes
- compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Biophysics (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Anesthesiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La invención proporciona composiciones líquidas en la forma de emulsiones físicamente estables que comprenden un alcano semifluorado. El alcano semifluorado está comprendido en la fase dispersa, la cual puede incluir también un ingrediente farmacéutico activo. Uno de los ingredientes activos preferido es propofol. Las composiciones son, opcionalmente, esterilizables por calor y pueden usarse para aplicaciones de producto farmacéuticas o cosméticas y administrarse tópicamente, intravenosamente o vía otras rutas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11150064 | 2011-01-04 | ||
| PCT/EP2012/050043 WO2012093113A1 (en) | 2011-01-04 | 2012-01-03 | O/w-emulsions comprising semifluorinated alkanes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2013007807A MX2013007807A (es) | 2013-12-16 |
| MX353154B true MX353154B (es) | 2017-12-20 |
Family
ID=43978091
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013007807A MX353154B (es) | 2011-01-04 | 2012-01-03 | Emulsiones de aceite/agua que comprenden alcanos semifluorados. |
Country Status (15)
| Country | Link |
|---|---|
| US (6) | US20140004197A1 (es) |
| EP (2) | EP2661280B1 (es) |
| JP (1) | JP6073244B2 (es) |
| KR (1) | KR101910213B1 (es) |
| CN (1) | CN103313729B (es) |
| AU (1) | AU2012204932B2 (es) |
| BR (1) | BR112013016661B1 (es) |
| CA (1) | CA2819988C (es) |
| DK (2) | DK3202421T3 (es) |
| ES (2) | ES2675242T3 (es) |
| MX (1) | MX353154B (es) |
| PL (2) | PL2661280T3 (es) |
| PT (2) | PT3202421T (es) |
| TR (2) | TR201808752T4 (es) |
| WO (1) | WO2012093113A1 (es) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10045996B2 (en) | 2010-03-17 | 2018-08-14 | Novaliq Gmbh | Pharmaceutical composition for treatment of increased intraocular pressure |
| EP2444063A1 (en) | 2010-10-20 | 2012-04-25 | Novaliq GmbH | Liquid pharmaceutical compositions for the delivery of active ingredients |
| EP2462921A1 (en) | 2010-11-11 | 2012-06-13 | Novaliq GmbH | Liquid pharmaceutical compositions for the treatment of a posterior eye disease |
| DK2714008T3 (en) | 2011-05-25 | 2017-03-13 | Novaliq Gmbh | PHARMACEUTICAL COMPOSITION FOR APPLICATION ON NAIL |
| EP2714010B1 (en) | 2011-05-25 | 2017-03-01 | Novaliq GmbH | Topical pharmaceutical composition based on semifluorinated alkanes |
| ES2625538T3 (es) | 2012-01-23 | 2017-07-19 | Novaliq Gmbh | Composiciones de proteínas estabilizadas basadas en alcanos semifluorados |
| BR112015005008B1 (pt) | 2012-09-12 | 2022-04-19 | Novaliq Gmbh | Composições de alcano semifluorado |
| CN104619314B (zh) | 2012-09-12 | 2017-09-22 | 诺瓦利克有限责任公司 | 包含半氟化烷烃的混合物的组合物 |
| GB2511028A (en) * | 2012-12-18 | 2014-08-27 | Univ Manchester Metropolitan | Nano emulsions, methods of forming the same and uses thereof |
| EP2783703A1 (en) * | 2013-03-25 | 2014-10-01 | B. Braun Melsungen AG | Semifluorocarbon compound containing contrast agent |
| CN114028560A (zh) | 2013-07-23 | 2022-02-11 | 诺瓦利克有限责任公司 | 稳定的抗体组合物 |
| AU2015227307A1 (en) * | 2014-03-03 | 2016-10-13 | Encore Vision, Inc. | Lipoic acid choline ester compositions and methods of use |
| CN108348777B (zh) | 2015-09-30 | 2020-04-28 | 诺瓦利克有限责任公司 | 半氟化化合物和其组合物 |
| CN113662929A (zh) | 2015-09-30 | 2021-11-19 | 诺瓦利克有限责任公司 | 用于眼部给药的半氟化化合物 |
| USRE50060E1 (en) | 2016-06-23 | 2024-07-30 | Novaliq Gmbh | Topical administration method |
| ES2969758T3 (es) | 2016-09-22 | 2024-05-22 | Novaliq Gmbh | Composiciones farmacéuticas para usar en la terapia de la blefaritis |
| KR20190057338A (ko) | 2016-09-23 | 2019-05-28 | 노바리크 게엠베하 | 시클로스포린을 포함하는 안과 조성물 |
| ES2819005T3 (es) | 2016-12-23 | 2021-04-14 | Novaliq Gmbh | Composición oftálmica para el tratamiento de la enfermedad del ojo seco |
| EP3612228B1 (en) | 2017-04-21 | 2023-08-23 | Dermaliq Therapeutics, Inc. | Iodine compositions |
| EP3619186B1 (en) | 2017-05-05 | 2021-02-17 | Novaliq GmbH | Process for the production of semifluorinated alkanes |
| US11278503B2 (en) | 2017-05-12 | 2022-03-22 | Novaliq Gmbh | Pharmaceutical compositions comprising semifluorinated alkanes for the treatment of contact lense-related conditions |
| MX2020003534A (es) | 2017-09-27 | 2020-07-29 | Novaliq Gmbh | Composiciones oftalmicas que comprenden latanoprost para usarse en el tratamiento de las enfermedades oculares. |
| CN111182893A (zh) | 2017-10-04 | 2020-05-19 | 诺瓦利克有限责任公司 | 包含f6h8的眼用组合物 |
| AU2019228119A1 (en) | 2018-03-02 | 2020-09-10 | Novaliq Gmbh | Pharmaceutical compositions comprising nebivolol |
| IL276888B2 (en) | 2018-03-28 | 2024-12-01 | Novaliq Gmbh | Pharmaceutical composition comprising timolol |
| EP3784246A1 (en) | 2018-04-27 | 2021-03-03 | Novaliq GmbH | Ophthalmic compositions comprising tafluprost for the treatment of glaucoma |
| EP3856124A1 (en) | 2018-09-27 | 2021-08-04 | Novaliq GmbH | Lipid barrier repair |
| ES2950878T3 (es) | 2018-09-27 | 2023-10-16 | Dermaliq Therapeutics Inc | Formulación de protección solar de uso tópico |
| CN112823020A (zh) | 2018-10-12 | 2021-05-18 | 诺瓦利克有限责任公司 | 用于治疗干眼病的眼用组合物 |
| EP3923907B1 (en) | 2019-02-13 | 2024-09-25 | Novaliq GmbH | Compositions and methods for the treatment of ocular neovascularization |
| US11439653B1 (en) | 2021-03-30 | 2022-09-13 | Epalex Corporation | Fospropofol formulations |
| US11478490B1 (en) | 2021-03-30 | 2022-10-25 | Epalex Corporation | Fospropofol formulations |
| US11628178B2 (en) | 2019-03-26 | 2023-04-18 | Epalex Corporation | Fospropofol methods and compositions |
| US11547714B2 (en) | 2020-02-05 | 2023-01-10 | Epalex Corporation | Fospropofol salts, methods and compositions |
| AU2020340561B2 (en) | 2019-09-06 | 2026-01-22 | Novaliq Gmbh | Ophthalmic composition for the treatment of uveitis |
| EP3912621A1 (en) * | 2020-05-19 | 2021-11-24 | tesa Labtec GmbH | Propofol for diagnosis of primary headache |
| FR3112475B1 (fr) | 2020-07-20 | 2023-11-10 | Naos Inst Of Life Science | formulation écobiologique, compatible avec la vie cellulaire, utilisable dans les domaines cosmétiques, dermopharmaceutiques ou vétérinaires |
| JP2024508686A (ja) * | 2021-02-05 | 2024-02-28 | エパレックス コーポレーション | フォスプロポフォールの方法及び組成物 |
| DE102021005495A1 (de) | 2021-11-06 | 2023-05-11 | Kocher-Plastik Maschinenbau Gmbh | Trennvorrichtung |
| DE102021005494A1 (de) | 2021-11-06 | 2023-05-11 | Kocher-Plastik Maschinenbau Gmbh | Trennvorrichtung |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5077036A (en) * | 1986-01-14 | 1991-12-31 | Alliance Pharmaceutical Corp. | Biocompatible stable fluorocarbon emulsions for contrast enhancement and oxygen transport comprising 40-125% wt./volume fluorocarbon combined with a phospholipid |
| FR2679150A1 (fr) * | 1991-07-17 | 1993-01-22 | Atta | Preparations comprenant un fluorocarbure ou compose hautement fluore et un compose organique lipophile-fluorophile, et leurs utilisations. |
| DE19536504C2 (de) * | 1995-09-29 | 1999-09-23 | H Meinert | Verwendung fluorierter Alkane |
| DE19709704C2 (de) * | 1997-03-10 | 1999-11-04 | Michael Georgieff | Verwendung einer flüssigen Präparation von Xenon zur intravenösen Verabreichung bei Einleitung und/oder Aufrechterhaltung der Anaesthesie |
| JP4198318B2 (ja) * | 1998-08-19 | 2008-12-17 | ヤーゴテック アクチェンゲゼルシャフト | プロポフォールの注射可能水性分散物 |
| US6140374A (en) | 1998-10-23 | 2000-10-31 | Abbott Laboratories | Propofol composition |
| AU3898700A (en) | 1999-03-15 | 2000-10-04 | John Claude Krusz | Treatment of acute headaches and chronic pain using rapidly-cleared anesthetic drug at sub-anesthetic dosages |
| US6177477B1 (en) * | 1999-03-24 | 2001-01-23 | American Home Products Corporation | Propofol formulation containing TRIS |
| US6399087B1 (en) * | 2000-12-20 | 2002-06-04 | Amphastar Pharmaceuticals, Inc. | Propofol formulation with enhanced microbial inhibition |
| WO2002089849A1 (en) * | 2001-05-07 | 2002-11-14 | Corium International | Compositions and delivery systems for administration of a local anesthetic agent |
| CA2540621A1 (en) * | 2003-11-19 | 2005-06-09 | Barnes-Jewish Hospital | Enhanced drug delivery |
| TWI368505B (en) * | 2005-05-24 | 2012-07-21 | Wyeth Corp | Versatile high load concentrate compositions for control of ecto-parasites |
| EP1922060B1 (en) | 2005-08-05 | 2009-01-14 | Bharat Serums & Vaccines Ltd. | Intravenous propofol emulsion compositions having preservative efficacy |
| TWI376239B (en) * | 2006-02-01 | 2012-11-11 | Andrew Xian Chen | Vitamin e succinate stabilized pharmaceutical compositions, methods for the preparation and the use thereof |
| EP2110126B9 (de) | 2008-04-18 | 2012-09-19 | Novaliq GmbH | Inhalative und instillative Verwendung von semifluorierten Alkanen als Wirkstoffträger im intrapulmonalen Bereich |
-
2012
- 2012-01-03 KR KR1020137018703A patent/KR101910213B1/ko active Active
- 2012-01-03 PT PT171597883T patent/PT3202421T/pt unknown
- 2012-01-03 EP EP12700455.4A patent/EP2661280B1/en not_active Not-in-force
- 2012-01-03 US US13/978,334 patent/US20140004197A1/en not_active Abandoned
- 2012-01-03 ES ES17159788.3T patent/ES2675242T3/es active Active
- 2012-01-03 CA CA2819988A patent/CA2819988C/en active Active
- 2012-01-03 PT PT12700455T patent/PT2661280T/pt unknown
- 2012-01-03 EP EP17159788.3A patent/EP3202421B1/en active Active
- 2012-01-03 CN CN201280004613.1A patent/CN103313729B/zh active Active
- 2012-01-03 BR BR112013016661-4A patent/BR112013016661B1/pt active IP Right Grant
- 2012-01-03 TR TR2018/08752T patent/TR201808752T4/tr unknown
- 2012-01-03 JP JP2013546732A patent/JP6073244B2/ja not_active Expired - Fee Related
- 2012-01-03 WO PCT/EP2012/050043 patent/WO2012093113A1/en not_active Ceased
- 2012-01-03 ES ES12700455T patent/ES2711760T3/es active Active
- 2012-01-03 DK DK17159788.3T patent/DK3202421T3/en active
- 2012-01-03 PL PL12700455T patent/PL2661280T3/pl unknown
- 2012-01-03 AU AU2012204932A patent/AU2012204932B2/en active Active
- 2012-01-03 MX MX2013007807A patent/MX353154B/es active IP Right Grant
- 2012-01-03 PL PL17159788T patent/PL3202421T3/pl unknown
- 2012-01-03 DK DK12700455.4T patent/DK2661280T3/en active
- 2012-01-03 TR TR2019/01309T patent/TR201901309T4/tr unknown
-
2017
- 2017-04-19 US US15/491,521 patent/US20170216204A1/en not_active Abandoned
-
2019
- 2019-01-28 US US16/259,037 patent/US20190224123A1/en not_active Abandoned
-
2020
- 2020-04-30 US US16/863,918 patent/US20200360285A1/en not_active Abandoned
-
2022
- 2022-12-23 US US18/146,306 patent/US20230139672A1/en not_active Abandoned
-
2025
- 2025-07-18 US US19/274,087 patent/US20250345276A1/en active Pending
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |