MX2018001584A - Composiciones de solución sólida para aines. - Google Patents
Composiciones de solución sólida para aines.Info
- Publication number
- MX2018001584A MX2018001584A MX2018001584A MX2018001584A MX2018001584A MX 2018001584 A MX2018001584 A MX 2018001584A MX 2018001584 A MX2018001584 A MX 2018001584A MX 2018001584 A MX2018001584 A MX 2018001584A MX 2018001584 A MX2018001584 A MX 2018001584A
- Authority
- MX
- Mexico
- Prior art keywords
- namely
- weight
- nsaids
- solid solution
- room temperature
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Una composición farmacéutica para el tratamiento contra la inflamación o del dolor o de la inflamación crónica que es líquida a la temperatura normal del cuerpo humano, más precisamente, a una temperatura de 37°C, que es sólida a temperatura ambiente, es decir, a una temperatura de 20°C, y que contiene: a) del 25% a 31% en peso de un fármaco antiinflamatorio no esteroideo (AINE); b) del 34% al 40% en peso de un lípido el cual es sólido a temperatura ambiente, es decir, a una temperatura de 20°C; c) del 22% al 28% en peso de un lípido el cual es líquido a temperatura ambiente, es decir, a una temperatura de 20°C; y d) del 7% al 13% en peso de un agente estabilizante conteniendo un polímero líquido de glicol.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15180256.8A EP3127556A1 (en) | 2015-08-07 | 2015-08-07 | Solid solution compositions for nsaid |
| US14/821,687 US9744132B2 (en) | 2010-10-29 | 2015-08-07 | Solid solution compositions and use in chronic inflammation |
| PCT/EP2016/068900 WO2017025517A1 (en) | 2015-08-07 | 2016-08-08 | SOLID SOLUTION COMPOSITIONS FOR NSAIDs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2018001584A true MX2018001584A (es) | 2019-01-31 |
Family
ID=56800263
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018001584A MX2018001584A (es) | 2015-08-07 | 2016-08-08 | Composiciones de solución sólida para aines. |
Country Status (10)
| Country | Link |
|---|---|
| EP (2) | EP3988091A1 (es) |
| JP (1) | JP6989489B2 (es) |
| CN (1) | CN108025078A (es) |
| AU (1) | AU2016306610B2 (es) |
| CA (1) | CA2994899C (es) |
| ES (1) | ES2906571T3 (es) |
| IL (1) | IL257385A (es) |
| MX (1) | MX2018001584A (es) |
| PL (1) | PL3331568T3 (es) |
| WO (1) | WO2017025517A1 (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9271950B2 (en) | 2010-10-29 | 2016-03-01 | Infirst Healthcare Limited | Compositions for treating chronic inflammation and inflammatory diseases |
| US9744132B2 (en) | 2010-10-29 | 2017-08-29 | Infirst Healthcare Limited | Solid solution compositions and use in chronic inflammation |
| US11202831B2 (en) | 2010-10-29 | 2021-12-21 | Infirst Healthcare Limited | Solid solution compositions and use in cardiovascular disease |
| US9504664B2 (en) | 2010-10-29 | 2016-11-29 | Infirst Healthcare Limited | Compositions and methods for treating severe pain |
| US9308213B2 (en) | 2010-10-29 | 2016-04-12 | Infirst Healthcare Limited | Solid solution compositions and use in chronic inflammation |
| US8895536B2 (en) | 2010-10-29 | 2014-11-25 | Infirst Healthcare Ltd. | Compositions and methods for treating chronic inflammation and inflammatory diseases |
| US11224659B2 (en) | 2010-10-29 | 2022-01-18 | Infirst Healthcare Limited | Solid solution compositions and use in severe pain |
| US10695431B2 (en) | 2010-10-29 | 2020-06-30 | Infirst Healthcare Limited | Solid solution compositions and use in cardiovascular disease |
| US10695432B2 (en) | 2010-10-29 | 2020-06-30 | Infirst Healthcare Limited | Solid solution compositions and use in severe pain |
| US11730709B2 (en) | 2010-10-29 | 2023-08-22 | Infirst Healthcare Limited | Compositions and methods for treating severe pain |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0000773D0 (sv) * | 2000-03-08 | 2000-03-08 | Astrazeneca Ab | New formulation |
| US9308213B2 (en) * | 2010-10-29 | 2016-04-12 | Infirst Healthcare Limited | Solid solution compositions and use in chronic inflammation |
| US10695432B2 (en) * | 2010-10-29 | 2020-06-30 | Infirst Healthcare Limited | Solid solution compositions and use in severe pain |
| CN104981253B (zh) * | 2013-01-14 | 2019-05-10 | 因佛斯特医疗有限公司 | 固溶体组合物及其在慢性炎症中的用途 |
-
2016
- 2016-08-08 EP EP21214529.6A patent/EP3988091A1/en active Pending
- 2016-08-08 CN CN201680054597.5A patent/CN108025078A/zh active Pending
- 2016-08-08 PL PL16756963T patent/PL3331568T3/pl unknown
- 2016-08-08 MX MX2018001584A patent/MX2018001584A/es unknown
- 2016-08-08 EP EP16756963.1A patent/EP3331568B1/en active Active
- 2016-08-08 CA CA2994899A patent/CA2994899C/en active Active
- 2016-08-08 JP JP2018506262A patent/JP6989489B2/ja active Active
- 2016-08-08 WO PCT/EP2016/068900 patent/WO2017025517A1/en active Application Filing
- 2016-08-08 ES ES16756963T patent/ES2906571T3/es active Active
- 2016-08-08 AU AU2016306610A patent/AU2016306610B2/en active Active
-
2018
- 2018-02-07 IL IL257385A patent/IL257385A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP6989489B2 (ja) | 2022-01-05 |
| EP3331568B1 (en) | 2021-12-15 |
| EP3331568A1 (en) | 2018-06-13 |
| CA2994899A1 (en) | 2017-02-16 |
| CA2994899C (en) | 2024-04-16 |
| JP2018526351A (ja) | 2018-09-13 |
| ES2906571T3 (es) | 2022-04-19 |
| CN108025078A (zh) | 2018-05-11 |
| WO2017025517A1 (en) | 2017-02-16 |
| IL257385A (en) | 2018-04-30 |
| AU2016306610A1 (en) | 2018-03-01 |
| PL3331568T3 (pl) | 2022-02-28 |
| EP3988091A1 (en) | 2022-04-27 |
| AU2016306610B2 (en) | 2019-02-28 |
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