CL2019000821A1 - Composiciones, métodos y usos para inhibir la actividad arginasa. (divisional solicitud 201801134) - Google Patents

Composiciones, métodos y usos para inhibir la actividad arginasa. (divisional solicitud 201801134)

Info

Publication number
CL2019000821A1
CL2019000821A1 CL2019000821A CL2019000821A CL2019000821A1 CL 2019000821 A1 CL2019000821 A1 CL 2019000821A1 CL 2019000821 A CL2019000821 A CL 2019000821A CL 2019000821 A CL2019000821 A CL 2019000821A CL 2019000821 A1 CL2019000821 A1 CL 2019000821A1
Authority
CL
Chile
Prior art keywords
methods
compositions
divisional application
arginase activity
inhibit arginase
Prior art date
Application number
CL2019000821A
Other languages
English (en)
Inventor
Eric B Sjogren
Jim Li
Zandt Michael Van
Darren Whitehouse
Original Assignee
Calithera Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Calithera Biosciences Inc filed Critical Calithera Biosciences Inc
Publication of CL2019000821A1 publication Critical patent/CL2019000821A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507—Comprising a combination of two or more separate antibodies

Abstract

LA INVENCIÓN SE REFIERE A UNA NUEVA CLASE DE COMPUESTOS QUE EXHIBEN ACTIVIDAD INHIBIDORA DE LA ACTIVIDAD HACIA LA ARGINASA, Y COMPOSICIONES FARMACÉUTICAS QUE COMPRENDEN LOS COMPUESTOS DE LA INVENCIÓN. TAMBIÉN SE PROPORCIONAN EN EL PRESENTE DOCUMENTO LOS MÉTODOS PARA TRATAR EL CÁNCER CON LOS INHIBIDORES DE ARGINASA DE LA INVENCIÓN.
CL2019000821A 2015-10-30 2019-03-28 Composiciones, métodos y usos para inhibir la actividad arginasa. (divisional solicitud 201801134) CL2019000821A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562248632P 2015-10-30 2015-10-30
US201662281964P 2016-01-22 2016-01-22
US201662323034P 2016-04-15 2016-04-15

Publications (1)

Publication Number Publication Date
CL2019000821A1 true CL2019000821A1 (es) 2019-08-09

Family

ID=58631120

Family Applications (4)

Application Number Title Priority Date Filing Date
CL2018001134A CL2018001134A1 (es) 2015-10-30 2018-04-27 Composiciones y métodos para inhibir la actividad arginasa
CL2019000821A CL2019000821A1 (es) 2015-10-30 2019-03-28 Composiciones, métodos y usos para inhibir la actividad arginasa. (divisional solicitud 201801134)
CL2019000820A CL2019000820A1 (es) 2015-10-30 2019-03-28 Compuestos, composiciones y sus usos para inhibir la actividad arginasa. (divisional solicitud 201801134)
CL2019000819A CL2019000819A1 (es) 2015-10-30 2019-03-28 Compuestos y composiciones para inhibir la actividad arginasa. (divisional solicitud 201801134)

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CL2018001134A CL2018001134A1 (es) 2015-10-30 2018-04-27 Composiciones y métodos para inhibir la actividad arginasa

Family Applications After (2)

Application Number Title Priority Date Filing Date
CL2019000820A CL2019000820A1 (es) 2015-10-30 2019-03-28 Compuestos, composiciones y sus usos para inhibir la actividad arginasa. (divisional solicitud 201801134)
CL2019000819A CL2019000819A1 (es) 2015-10-30 2019-03-28 Compuestos y composiciones para inhibir la actividad arginasa. (divisional solicitud 201801134)

Country Status (36)

Country Link
US (4) US10065974B2 (es)
EP (3) EP3693375B1 (es)
JP (3) JP6833844B2 (es)
KR (2) KR20220118559A (es)
CN (4) CN108271371B (es)
AU (3) AU2016343656B2 (es)
BR (3) BR122020022280B1 (es)
CA (1) CA3003271A1 (es)
CL (4) CL2018001134A1 (es)
CO (1) CO2018004750A2 (es)
CR (3) CR20210390A (es)
CY (1) CY1123557T1 (es)
DK (1) DK3368541T3 (es)
EA (1) EA038276B1 (es)
EC (1) ECSP18040250A (es)
ES (2) ES2808988T3 (es)
HK (1) HK1252560A1 (es)
HR (1) HRP20201046T1 (es)
HU (1) HUE054972T2 (es)
IL (3) IL258731B (es)
LT (1) LT3368541T (es)
MA (2) MA50636A (es)
MD (1) MD3368541T2 (es)
MX (1) MX2018005294A (es)
MY (1) MY201783A (es)
NZ (1) NZ742742A (es)
PH (1) PH12018500899A1 (es)
PL (1) PL3368541T3 (es)
PT (1) PT3368541T (es)
RS (1) RS60695B1 (es)
SG (4) SG10201911402YA (es)
SI (1) SI3368541T1 (es)
TW (3) TWI710565B (es)
UA (1) UA125289C2 (es)
WO (1) WO2017075363A1 (es)
ZA (4) ZA201803556B (es)

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Publication number Publication date
CR20210389A (es) 2021-09-16
CY1123557T1 (el) 2022-03-24
KR20180084063A (ko) 2018-07-24
CL2018001134A1 (es) 2018-10-26
TWI710565B (zh) 2020-11-21
ZA201803556B (en) 2021-02-24
AU2016343656A1 (en) 2018-06-07
CN108271371A (zh) 2018-07-10
ECSP18040250A (es) 2018-10-31
EA038276B1 (ru) 2021-08-04
PT3368541T (pt) 2020-07-06
IL258731A (en) 2018-06-28
PH12018500899A1 (en) 2018-10-29
DK3368541T3 (da) 2020-06-29
HK1252560A1 (zh) 2019-05-31
MY201783A (en) 2024-03-18
ZA201907091B (en) 2021-05-26
MD3368541T2 (ro) 2020-09-30
US20200223872A1 (en) 2020-07-16
US20170121352A1 (en) 2017-05-04
TW202146028A (zh) 2021-12-16
US10851118B2 (en) 2020-12-01
SG11201802961PA (en) 2018-05-30
IL281503A (en) 2021-04-29
ZA201907093B (en) 2021-03-31
WO2017075363A1 (en) 2017-05-04
EP4011887A1 (en) 2022-06-15
RS60695B1 (sr) 2020-09-30
US20180346489A1 (en) 2018-12-06
NZ742742A (en) 2023-04-28
SG10202003966RA (en) 2020-06-29
SG10201911402YA (en) 2020-02-27
EP3693375B1 (en) 2022-02-16
TWI775556B (zh) 2022-08-21
IL288225A (en) 2022-01-01
AU2020286278A1 (en) 2021-01-14
ES2808988T3 (es) 2021-03-02
ES2910928T3 (es) 2022-05-17
HUE054972T2 (hu) 2021-10-28
US10065974B2 (en) 2018-09-04
UA125289C2 (uk) 2022-02-16
LT3368541T (lt) 2020-09-25
MA50636A (fr) 2021-04-14
TW202110858A (zh) 2021-03-16
CN113150016A (zh) 2021-07-23
CR20210390A (es) 2021-10-19
JP6833844B2 (ja) 2021-02-24
MA43131B1 (fr) 2020-07-29
CL2019000820A1 (es) 2019-08-09
US10844080B2 (en) 2020-11-24
AU2016343656B2 (en) 2020-09-17
KR20220118559A (ko) 2022-08-25
CN113150015A (zh) 2021-07-23
BR122020022280B1 (pt) 2022-05-03
CR20180282A (es) 2018-11-30
JP2022071010A (ja) 2022-05-13
MX2018005294A (es) 2018-09-21
CN113201002A (zh) 2021-08-03
TWI734630B (zh) 2021-07-21
EP3368541A1 (en) 2018-09-05
BR112018008746B1 (pt) 2021-11-16
CN108271371B (zh) 2021-02-09
HRP20201046T1 (hr) 2020-10-16
EP3368541A4 (en) 2019-07-17
SG10201911406TA (en) 2020-01-30
AU2020286278B2 (en) 2022-03-17
EP3368541B1 (en) 2020-05-27
ZA201907092B (en) 2021-04-28
BR122020022275B1 (pt) 2022-05-03
TW201726692A (zh) 2017-08-01
EP3693375A1 (en) 2020-08-12
BR112018008746A8 (pt) 2019-02-26
SI3368541T1 (sl) 2020-10-30
IL258731B (en) 2021-04-29
CL2019000819A1 (es) 2019-08-09
AU2022203703A1 (en) 2022-06-16
IL281503B (en) 2022-01-01
US20210061822A1 (en) 2021-03-04
CO2018004750A2 (es) 2018-10-31
JP2021075543A (ja) 2021-05-20
CA3003271A1 (en) 2017-05-04
EA201891057A1 (ru) 2018-12-28
BR112018008746A2 (pt) 2018-10-30
KR102434308B1 (ko) 2022-08-19
JP2018533582A (ja) 2018-11-15
JP7032583B2 (ja) 2022-03-08
PL3368541T3 (pl) 2020-11-02

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