CA2998269C - Semifluorinated compounds for ophthalmic administration - Google Patents

Semifluorinated compounds for ophthalmic administration Download PDF

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Publication number
CA2998269C
CA2998269C CA2998269A CA2998269A CA2998269C CA 2998269 C CA2998269 C CA 2998269C CA 2998269 A CA2998269 A CA 2998269A CA 2998269 A CA2998269 A CA 2998269A CA 2998269 C CA2998269 C CA 2998269C
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CA
Canada
Prior art keywords
composition
eye
compound
ophthalmic
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2998269A
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English (en)
French (fr)
Other versions
CA2998269A1 (en
Inventor
Dieter Scherer
Ralf Grillenberger
Frank Loscher
Hartmut Voss
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novaliq GmbH
Original Assignee
Novaliq GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novaliq GmbH filed Critical Novaliq GmbH
Publication of CA2998269A1 publication Critical patent/CA2998269A1/en
Application granted granted Critical
Publication of CA2998269C publication Critical patent/CA2998269C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/02Halogenated hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008Introducing ophthalmic products into the ocular cavity or retaining products therein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00Preparation of halogenated hydrocarbons
    • C07C17/26Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
    • C07C17/263Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
    • C07C17/266Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions of hydrocarbons and halogenated hydrocarbons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C19/00Acyclic saturated compounds containing halogen atoms
    • C07C19/08Acyclic saturated compounds containing halogen atoms containing fluorine

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
CA2998269A 2015-09-30 2016-09-29 Semifluorinated compounds for ophthalmic administration Active CA2998269C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP15187760.2 2015-09-30
EP15187760 2015-09-30
EP15192429.7 2015-10-30
EP15192429 2015-10-30
PCT/EP2016/073262 WO2017055453A1 (en) 2015-09-30 2016-09-29 Semifluorinated compounds for ophthalmic administration

Publications (2)

Publication Number Publication Date
CA2998269A1 CA2998269A1 (en) 2017-04-06
CA2998269C true CA2998269C (en) 2021-03-23

Family

ID=57068093

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2998269A Active CA2998269C (en) 2015-09-30 2016-09-29 Semifluorinated compounds for ophthalmic administration

Country Status (14)

Country Link
US (2) US11154513B2 (enExample)
EP (3) EP4234523A1 (enExample)
JP (2) JP6642935B2 (enExample)
KR (2) KR102584063B1 (enExample)
CN (4) CN113662929A (enExample)
AU (3) AU2016329261B2 (enExample)
CA (1) CA2998269C (enExample)
DE (1) DE202016008739U1 (enExample)
DK (2) DK3356313T3 (enExample)
ES (2) ES2803248T3 (enExample)
MX (2) MX2018003781A (enExample)
PL (2) PL3722274T3 (enExample)
PT (1) PT3356313T (enExample)
WO (1) WO2017055453A1 (enExample)

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AU2020340561A1 (en) 2019-09-06 2022-03-31 Novaliq Gmbh Ophthalmic composition for the treatment of uveitis

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