AU2016329261B2 - Semifluorinated compounds for ophthalmic administration - Google Patents

Semifluorinated compounds for ophthalmic administration Download PDF

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Publication number
AU2016329261B2
AU2016329261B2 AU2016329261A AU2016329261A AU2016329261B2 AU 2016329261 B2 AU2016329261 B2 AU 2016329261B2 AU 2016329261 A AU2016329261 A AU 2016329261A AU 2016329261 A AU2016329261 A AU 2016329261A AU 2016329261 B2 AU2016329261 B2 AU 2016329261B2
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AU
Australia
Prior art keywords
composition
eye
symptoms
itching
ophthalmic
Prior art date
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Active
Application number
AU2016329261A
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English (en)
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AU2016329261A1 (en
Inventor
Ralf Grillenberger
Frank Loscher
Dieter Scherer
Hartmut Voss
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Novaliq GmbH
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Novaliq GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novaliq GmbH filed Critical Novaliq GmbH
Publication of AU2016329261A1 publication Critical patent/AU2016329261A1/en
Application granted granted Critical
Publication of AU2016329261B2 publication Critical patent/AU2016329261B2/en
Priority to AU2020205239A priority Critical patent/AU2020205239B9/en
Priority to AU2022200366A priority patent/AU2022200366B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/02—Halogenated hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
    • C07C17/263—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
    • C07C17/266—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions of hydrocarbons and halogenated hydrocarbons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C19/00—Acyclic saturated compounds containing halogen atoms
    • C07C19/08—Acyclic saturated compounds containing halogen atoms containing fluorine

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
AU2016329261A 2015-09-30 2016-09-29 Semifluorinated compounds for ophthalmic administration Active AU2016329261B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2020205239A AU2020205239B9 (en) 2015-09-30 2020-07-14 Semifluorinated compounds for ophthalmic administration
AU2022200366A AU2022200366B2 (en) 2015-09-30 2022-01-20 Semifluorinated compounds for ophthalmic administration

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP15187760.2 2015-09-30
EP15187760 2015-09-30
EP15192429.7 2015-10-30
EP15192429 2015-10-30
PCT/EP2016/073262 WO2017055453A1 (en) 2015-09-30 2016-09-29 Semifluorinated compounds for ophthalmic administration

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2020205239A Division AU2020205239B9 (en) 2015-09-30 2020-07-14 Semifluorinated compounds for ophthalmic administration

Publications (2)

Publication Number Publication Date
AU2016329261A1 AU2016329261A1 (en) 2018-04-12
AU2016329261B2 true AU2016329261B2 (en) 2020-05-07

Family

ID=57068093

Family Applications (3)

Application Number Title Priority Date Filing Date
AU2016329261A Active AU2016329261B2 (en) 2015-09-30 2016-09-29 Semifluorinated compounds for ophthalmic administration
AU2020205239A Active AU2020205239B9 (en) 2015-09-30 2020-07-14 Semifluorinated compounds for ophthalmic administration
AU2022200366A Active AU2022200366B2 (en) 2015-09-30 2022-01-20 Semifluorinated compounds for ophthalmic administration

Family Applications After (2)

Application Number Title Priority Date Filing Date
AU2020205239A Active AU2020205239B9 (en) 2015-09-30 2020-07-14 Semifluorinated compounds for ophthalmic administration
AU2022200366A Active AU2022200366B2 (en) 2015-09-30 2022-01-20 Semifluorinated compounds for ophthalmic administration

Country Status (14)

Country Link
US (2) US11154513B2 (enExample)
EP (3) EP4234523A1 (enExample)
JP (2) JP6642935B2 (enExample)
KR (2) KR102584063B1 (enExample)
CN (4) CN110693825B (enExample)
AU (3) AU2016329261B2 (enExample)
CA (1) CA2998269C (enExample)
DE (1) DE202016008739U1 (enExample)
DK (2) DK3356313T3 (enExample)
ES (2) ES2953837T3 (enExample)
MX (2) MX2018003781A (enExample)
PL (2) PL3356313T3 (enExample)
PT (1) PT3356313T (enExample)
WO (1) WO2017055453A1 (enExample)

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BR112012023421B1 (pt) 2010-03-17 2021-09-14 Novaliq Gmbh Composição farmacêutica para tratamento de aumento de pressão intraocular
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EP2462921A1 (en) 2010-11-11 2012-06-13 Novaliq GmbH Liquid pharmaceutical compositions for the treatment of a posterior eye disease
DK3192501T3 (da) 2011-05-25 2020-08-03 Novaliq Gmbh Topisk farmaceutisk sammensætning baseret på semifluorerede alkaner
US9757460B2 (en) 2012-01-23 2017-09-12 Novaliq Gmbh Stabilised protein compositions based on semifluorinated alkanes
CN113679699B (zh) 2012-09-12 2022-10-28 诺瓦利克有限责任公司 包含半氟化烷烃的混合物的组合物
WO2014041071A1 (en) 2012-09-12 2014-03-20 Novaliq Gmbh Semifluorinated alkane compositions
CN105555311B (zh) 2013-07-23 2021-10-08 诺瓦利克有限责任公司 稳定的抗体组合物
DK3495023T3 (da) 2015-09-30 2020-07-20 Novaliq Gmbh Semifluorerede forbindelser og sammensætninger deraf
EP4234523A1 (en) * 2015-09-30 2023-08-30 Novaliq GmbH Semifluorinated compounds for ophthalmic administration
AU2017281296B2 (en) 2016-06-23 2021-03-11 Novaliq Gmbh Topical administration method
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EP3619186B1 (en) 2017-05-05 2021-02-17 Novaliq GmbH Process for the production of semifluorinated alkanes
US11278503B2 (en) 2017-05-12 2022-03-22 Novaliq Gmbh Pharmaceutical compositions comprising semifluorinated alkanes for the treatment of contact lense-related conditions
CN111372566A (zh) 2017-09-27 2020-07-03 诺瓦利克有限责任公司 用于治疗眼部疾病的包含拉坦前列素的眼科用组合物
CN119909046A (zh) 2017-10-04 2025-05-02 诺瓦利克有限责任公司 包含f6h8的眼用组合物
KR20200128407A (ko) 2018-03-02 2020-11-12 노바리크 게엠베하 네비볼롤을 포함하는 약제학적 조성물
WO2019206956A1 (en) 2018-04-27 2019-10-31 Novaliq Gmbh Ophthalmic compositions comprising tafluprost for the treatment of glaucoma
CN112739311B (zh) 2018-09-27 2023-07-14 德马利克治疗公司 局部用防晒配制品
CA3112504A1 (en) 2018-09-27 2020-04-02 Novaliq Gmbh Lipid barrier repair
WO2020074697A1 (en) 2018-10-12 2020-04-16 Novaliq Gmbh Ophthalmic composition for treatment of dry eye disease
EP3923907B1 (en) 2019-02-13 2024-09-25 Novaliq GmbH Compositions and methods for the treatment of ocular neovascularization
AU2020340561B2 (en) 2019-09-06 2026-01-22 Novaliq Gmbh Ophthalmic composition for the treatment of uveitis

Citations (1)

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WO2014041055A1 (en) * 2012-09-12 2014-03-20 Novaliq Gmbh Compositions comprising mixtures of semifluorinated alkanes

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