KR102154415B1 - 부분불소화 화합물 - Google Patents

부분불소화 화합물 Download PDF

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Publication number
KR102154415B1
KR102154415B1 KR1020187010285A KR20187010285A KR102154415B1 KR 102154415 B1 KR102154415 B1 KR 102154415B1 KR 1020187010285 A KR1020187010285 A KR 1020187010285A KR 20187010285 A KR20187010285 A KR 20187010285A KR 102154415 B1 KR102154415 B1 KR 102154415B1
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South Korea
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composition
eye
compound
partially fluorinated
compounds
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Korean (ko)
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KR20180059823A (ko
Inventor
디터 쉐러
랄프 그릴렌버거
프랑크 로셔
하르트무트 보스
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노바리크 게엠베하
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/02—Halogenated hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
    • C07C17/263—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
    • C07C17/266—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions of hydrocarbons and halogenated hydrocarbons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C19/00—Acyclic saturated compounds containing halogen atoms
    • C07C19/08—Acyclic saturated compounds containing halogen atoms containing fluorine

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
KR1020187010285A 2015-09-30 2016-09-29 부분불소화 화합물 Active KR102154415B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020207025363A KR102584063B1 (ko) 2015-09-30 2016-09-29 부분불소화 화합물

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP15187760.2 2015-09-30
EP15187760 2015-09-30
EP15192429.7 2015-10-30
EP15192429 2015-10-30
PCT/EP2016/073262 WO2017055453A1 (en) 2015-09-30 2016-09-29 Semifluorinated compounds for ophthalmic administration

Related Child Applications (1)

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KR1020207025363A Division KR102584063B1 (ko) 2015-09-30 2016-09-29 부분불소화 화합물

Publications (2)

Publication Number Publication Date
KR20180059823A KR20180059823A (ko) 2018-06-05
KR102154415B1 true KR102154415B1 (ko) 2020-09-10

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KR1020207025363A Active KR102584063B1 (ko) 2015-09-30 2016-09-29 부분불소화 화합물

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Country Status (14)

Country Link
US (2) US11154513B2 (enExample)
EP (3) EP4234523A1 (enExample)
JP (2) JP6642935B2 (enExample)
KR (2) KR102154415B1 (enExample)
CN (4) CN113662928A (enExample)
AU (3) AU2016329261B2 (enExample)
CA (1) CA2998269C (enExample)
DE (1) DE202016008739U1 (enExample)
DK (2) DK3356313T3 (enExample)
ES (2) ES2803248T3 (enExample)
MX (2) MX2018003781A (enExample)
PL (2) PL3722274T3 (enExample)
PT (1) PT3356313T (enExample)
WO (1) WO2017055453A1 (enExample)

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EP3181119B1 (en) 2012-09-12 2019-07-10 Novaliq GmbH Semifluorinated alkane compositions for use in the treatment of keratoconjunctivitis sicca
PT3024484T (pt) 2013-07-23 2018-10-24 Novaliq Gmbh Composições de anticorpo estabilizadas
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CN111743882A (zh) 2015-09-30 2020-10-09 诺瓦利克有限责任公司 半氟化化合物和其组合物
CN109640900B (zh) 2016-06-23 2020-07-07 诺瓦利克有限责任公司 一种试剂盒
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KR102288022B1 (ko) * 2016-12-23 2021-08-10 노바리크 게엠베하 건성 안 질환 치료용 안구 조성물
MX388460B (es) 2017-04-21 2025-03-20 Dermaliq Therapeutics Inc Composiciones de yodo.
WO2018202835A1 (en) 2017-05-05 2018-11-08 Novaliq Gmbh Process for the production of semifluorinated alkanes
CN110650734B (zh) * 2017-05-12 2024-11-15 诺瓦利克有限责任公司 治疗与隐形眼镜有关病症的包含半氟化烷烃的药物组合物
KR20200059272A (ko) 2017-09-27 2020-05-28 노바리크 게엠베하 안구 질환의 치료에서의 사용을 위한 라타노프로스트를 포함하는 안과적 조성물
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CN112153970A (zh) 2018-04-27 2020-12-29 诺瓦利克有限责任公司 用于治疗青光眼的包含他氟前列素的眼用组合物
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