JP6602765B2 - クロマトグラフィー再使用のための方法 - Google Patents

クロマトグラフィー再使用のための方法 Download PDF

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JP6602765B2
JP6602765B2 JP2016540425A JP2016540425A JP6602765B2 JP 6602765 B2 JP6602765 B2 JP 6602765B2 JP 2016540425 A JP2016540425 A JP 2016540425A JP 2016540425 A JP2016540425 A JP 2016540425A JP 6602765 B2 JP6602765 B2 JP 6602765B2
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antibody
protein
polypeptide
buffer
purification
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JP2016530533A (ja
JP2016530533A5 (https=
Inventor
エクタ マハジャン，
カピル コタリー，
ジョアンナ ソ，
ジェイ ワーバー，
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ジェネンテック， インコーポレイテッド
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/20—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the sorbent material
    • B01D15/203—Equilibration or regeneration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G or L chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J49/00—Regeneration or reactivation of ion-exchangers; Apparatus therefor
    • B01J49/60—Cleaning or rinsing ion-exchange beds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2016540425A 2013-09-05 2014-09-05 クロマトグラフィー再使用のための方法 Active JP6602765B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361874305P 2013-09-05 2013-09-05
US61/874,305 2013-09-05
PCT/US2014/054313 WO2015035180A1 (en) 2013-09-05 2014-09-05 Method for chromatography reuse

Related Child Applications (1)

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JP2018242197A Division JP2019094334A (ja) 2013-09-05 2018-12-26 クロマトグラフィー再使用のための方法

Publications (3)

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JP2016530533A JP2016530533A (ja) 2016-09-29
JP2016530533A5 JP2016530533A5 (https=) 2017-10-19
JP6602765B2 true JP6602765B2 (ja) 2019-11-06

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JP2016540425A Active JP6602765B2 (ja) 2013-09-05 2014-09-05 クロマトグラフィー再使用のための方法
JP2018242197A Withdrawn JP2019094334A (ja) 2013-09-05 2018-12-26 クロマトグラフィー再使用のための方法
JP2021088108A Withdrawn JP2021155421A (ja) 2013-09-05 2021-05-26 クロマトグラフィー再使用のための方法
JP2023035358A Pending JP2023085273A (ja) 2013-09-05 2023-03-08 クロマトグラフィー再使用のための方法
JP2025135562A Withdrawn JP2025186245A (ja) 2013-09-05 2025-08-15 クロマトグラフィー再使用のための方法

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JP2018242197A Withdrawn JP2019094334A (ja) 2013-09-05 2018-12-26 クロマトグラフィー再使用のための方法
JP2021088108A Withdrawn JP2021155421A (ja) 2013-09-05 2021-05-26 クロマトグラフィー再使用のための方法
JP2023035358A Pending JP2023085273A (ja) 2013-09-05 2023-03-08 クロマトグラフィー再使用のための方法
JP2025135562A Withdrawn JP2025186245A (ja) 2013-09-05 2025-08-15 クロマトグラフィー再使用のための方法

Country Status (9)

Country Link
US (2) US20150093800A1 (https=)
EP (1) EP3041593B1 (https=)
JP (5) JP6602765B2 (https=)
KR (1) KR20160050062A (https=)
CN (1) CN105848746B (https=)
CA (1) CA2922832A1 (https=)
MX (1) MX2016002798A (https=)
RU (1) RU2016112549A (https=)
WO (1) WO2015035180A1 (https=)

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WO2015035180A1 (en) 2015-03-12
EP3041593C0 (en) 2025-01-29
CN105848746B (zh) 2019-07-09
MX2016002798A (es) 2016-07-21
EP3041593A1 (en) 2016-07-13
EP3041593B1 (en) 2025-01-29
RU2016112549A (ru) 2017-10-10
CA2922832A1 (en) 2015-03-12
JP2016530533A (ja) 2016-09-29
US20190054396A1 (en) 2019-02-21
EP3041593A4 (en) 2017-08-30
JP2025186245A (ja) 2025-12-23
JP2019094334A (ja) 2019-06-20
JP2023085273A (ja) 2023-06-20
KR20160050062A (ko) 2016-05-10
US10940401B2 (en) 2021-03-09
JP2021155421A (ja) 2021-10-07
CN105848746A (zh) 2016-08-10
US20150093800A1 (en) 2015-04-02

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