JP6595984B2 - 腎機能に関連付けられるバイオマーカーおよびそれを使用する方法 - Google Patents

腎機能に関連付けられるバイオマーカーおよびそれを使用する方法 Download PDF

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JP6595984B2
JP6595984B2 JP2016514016A JP2016514016A JP6595984B2 JP 6595984 B2 JP6595984 B2 JP 6595984B2 JP 2016514016 A JP2016514016 A JP 2016514016A JP 2016514016 A JP2016514016 A JP 2016514016A JP 6595984 B2 JP6595984 B2 JP 6595984B2
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biomarkers
renal function
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JP2016520192A (ja
JP2016520192A5 (cg-RX-API-DMAC7.html
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ペリション、リージス
コブ、ジェフリー、エドモンド
ブラウン、メレディス、ブイ．
ケネディー、アダム
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メタボロン，インコーポレイテッド
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/64—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving ketones
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/70—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving creatine or creatinine
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00—Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/34—Genitourinary disorders
    • G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/56—Staging of a disease; Further complications associated with the disease

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  • Life Sciences & Earth Sciences (AREA)
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  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2016514016A 2013-05-14 2014-05-13 腎機能に関連付けられるバイオマーカーおよびそれを使用する方法 Active JP6595984B2 (ja)

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US201361822965P 2013-05-14 2013-05-14
US61/822,965 2013-05-14
PCT/US2014/037762 WO2014186311A1 (en) 2013-05-14 2014-05-13 Biomarkers related to kidney function and methods using the same

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JP2016520192A JP2016520192A (ja) 2016-07-11
JP2016520192A5 JP2016520192A5 (cg-RX-API-DMAC7.html) 2017-06-22
JP6595984B2 true JP6595984B2 (ja) 2019-10-23

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US (2) US10539575B2 (cg-RX-API-DMAC7.html)
EP (3) EP2997366B1 (cg-RX-API-DMAC7.html)
JP (1) JP6595984B2 (cg-RX-API-DMAC7.html)
CN (2) CN110196335A (cg-RX-API-DMAC7.html)
AU (1) AU2014265669B2 (cg-RX-API-DMAC7.html)
BR (1) BR112015028253A2 (cg-RX-API-DMAC7.html)
CA (2) CA3184836A1 (cg-RX-API-DMAC7.html)
ES (2) ES2702123T3 (cg-RX-API-DMAC7.html)
MX (2) MX391220B (cg-RX-API-DMAC7.html)
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EP3355914B1 (en) * 2015-09-29 2024-03-06 The General Hospital Corporation A composition comprising bcg for reducing cholesterol.
US20170234874A1 (en) * 2015-10-07 2017-08-17 Clearbridge Biophotonics Pte Ltd. Integrated visual morphology and cell protein expression using resonance-light scattering
US12057228B1 (en) * 2015-12-30 2024-08-06 Cerner Innovation, Inc. Predicting newly incident chronic kidney disease
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JP7393206B2 (ja) * 2016-12-19 2023-12-06 メタボロン，インコーポレイテッド 腎機能代謝産物の検出及び定量化のための質量分析アッセイ方法
CN108956790A (zh) * 2017-05-18 2018-12-07 中国人民解放军第二军医大学第二附属医院 一组氨基酸标志物在急性肾损伤诊断试剂盒中的应用
CN107132266A (zh) * 2017-06-21 2017-09-05 佛山科学技术学院 一种基于随机森林的水质分类方法及系统
EP4567822A3 (en) 2017-08-08 2025-09-10 Fresenius Medical Care Holdings, Inc. Systems and methods for treating and estimating progression of chronic kidney disease
CN107326093B (zh) * 2017-09-04 2020-01-21 东南大学 基于Taqman探针的慢性肾脏病相关基因检测荧光定量PCR一步法试剂盒及其应用
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CN113454462A (zh) * 2019-02-20 2021-09-28 株式会社合伙企业 固相反应芯片和使用该固相反应芯片的测定方法
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CN112305089B (zh) * 2019-07-26 2022-04-29 长沙都正生物科技股份有限公司 一种慢性肾病诊断生物标记物及其应用
CN111487338B (zh) * 2020-04-16 2022-06-10 中南大学湘雅二医院 一种与肾功能相关的无创生物标记物及其应用
WO2021232211A1 (zh) * 2020-05-19 2021-11-25 深圳市中医院 诊断肾病的标志物以及诊断方法
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JP2016520192A (ja) 2016-07-11
CN105209909A (zh) 2015-12-30
US20160116486A1 (en) 2016-04-28
MX2015015561A (es) 2016-02-05
EP3410115A1 (en) 2018-12-05
EP2997366A1 (en) 2016-03-23
CN110196335A (zh) 2019-09-03
EP2997366A4 (en) 2017-04-12
MX2019005748A (es) 2019-08-12
EP2997366B1 (en) 2018-10-10
CA2911204A1 (en) 2014-11-20
US20200103417A1 (en) 2020-04-02
WO2014186311A1 (en) 2014-11-20
CN105209909B (zh) 2019-06-07
CA3184836A1 (en) 2014-11-20
MX365061B (es) 2019-05-22
BR112015028253A2 (pt) 2017-07-25
AU2014265669A1 (en) 2015-12-24
AU2014265669B2 (en) 2020-05-14
EP3546940B1 (en) 2021-02-17
US10539575B2 (en) 2020-01-21
ES2871823T3 (es) 2021-11-02
HK1218331A1 (zh) 2017-02-10
EP3546940A1 (en) 2019-10-02
MX391220B (es) 2025-03-21
ES2702123T3 (es) 2019-02-27
HK1222905A1 (en) 2017-07-14
CA2911204C (en) 2023-03-28

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