MX2015015561A - Biomarcadores relacionados a la funcion renal y metodos para usar los mismos. - Google Patents

Biomarcadores relacionados a la funcion renal y metodos para usar los mismos.

Info

Publication number
MX2015015561A
MX2015015561A MX2015015561A MX2015015561A MX2015015561A MX 2015015561 A MX2015015561 A MX 2015015561A MX 2015015561 A MX2015015561 A MX 2015015561A MX 2015015561 A MX2015015561 A MX 2015015561A MX 2015015561 A MX2015015561 A MX 2015015561A
Authority
MX
Mexico
Prior art keywords
kidney function
methods
biomarkers
same
kidney
Prior art date
Application number
MX2015015561A
Other languages
English (en)
Other versions
MX365061B (es
Inventor
Meredith V Brown
Regis Perichon
Jeffery Edmond Cobb
Adam Kennedy
Original Assignee
Metabolon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metabolon Inc filed Critical Metabolon Inc
Publication of MX2015015561A publication Critical patent/MX2015015561A/es
Publication of MX365061B publication Critical patent/MX365061B/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/64—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving ketones
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/70—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving creatine or creatinine
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00—Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/34—Genitourinary disorders
    • G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/56—Staging of a disease; Further complications associated with the disease

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Se proporcionan biomarcadores de la función renal y métodos para usar los biomarcadores para evaluar la función renal, monitorear la función renal, diagnosticar lesiones renales agudas, y diagnosticar enfermedades renales crónicas. También se proporcionan modalidades de entidades de moléculas pequeñas como biomarcadores para enfermedades renales crónicas.
MX2015015561A 2013-05-14 2014-05-13 Biomarcadores relacionados a la funcion renal y metodos para usar los mismos. MX365061B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361822965P 2013-05-14 2013-05-14
PCT/US2014/037762 WO2014186311A1 (en) 2013-05-14 2014-05-13 Biomarkers related to kidney function and methods using the same

Publications (2)

Publication Number Publication Date
MX2015015561A true MX2015015561A (es) 2016-02-05
MX365061B MX365061B (es) 2019-05-22

Family

ID=51898805

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2015015561A MX365061B (es) 2013-05-14 2014-05-13 Biomarcadores relacionados a la funcion renal y metodos para usar los mismos.
MX2019005748A MX2019005748A (es) 2013-05-14 2015-11-10 Biomarcadores relacionados a la funcion renal y metodos para usar los mismos.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2019005748A MX2019005748A (es) 2013-05-14 2015-11-10 Biomarcadores relacionados a la funcion renal y metodos para usar los mismos.

Country Status (11)

Country Link
US (2) US10539575B2 (es)
EP (3) EP3546940B1 (es)
JP (1) JP6595984B2 (es)
CN (2) CN105209909B (es)
AU (1) AU2014265669B2 (es)
BR (1) BR112015028253A2 (es)
CA (2) CA2911204C (es)
ES (2) ES2871823T3 (es)
HK (2) HK1218331A1 (es)
MX (2) MX365061B (es)
WO (1) WO2014186311A1 (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105209909B (zh) * 2013-05-14 2019-06-07 梅塔博隆股份有限公司 与肾功能相关的生物标记及其使用方法
MX2017008904A (es) * 2015-01-09 2018-02-09 Global Genomics Group Llc Biomarcadores basados en sangre para diagnosticar enfermedad de arteria coronaria ateroesclerotica.
WO2016115496A1 (en) * 2015-01-15 2016-07-21 Joslin Diabetes Center Metabolite biomarkers predictive of renal disease in diabetic patients
US11266730B2 (en) 2015-09-29 2022-03-08 The General Hospital Corporation Methods of treating and diagnosing disease using biomarkers for BCG therapy
US20170234874A1 (en) * 2015-10-07 2017-08-17 Clearbridge Biophotonics Pte Ltd. Integrated visual morphology and cell protein expression using resonance-light scattering
US12057228B1 (en) * 2015-12-30 2024-08-06 Cerner Innovation, Inc. Predicting newly incident chronic kidney disease
EP3491004B1 (en) * 2016-07-28 2021-09-01 Metabolon, Inc. Diagnostic methods, therapeutic agents and uses thereof
WO2018097793A1 (en) * 2016-11-25 2018-05-31 Baeckhed Fredrik Metabolic disorders
CN110088615B (zh) * 2016-12-19 2023-08-22 梅塔博隆股份有限公司 用于肾功能代谢物的检测和定量的质谱法测定方法
CN108956790A (zh) * 2017-05-18 2018-12-07 中国人民解放军第二军医大学第二附属医院 一组氨基酸标志物在急性肾损伤诊断试剂盒中的应用
CN107132266A (zh) * 2017-06-21 2017-09-05 佛山科学技术学院 一种基于随机森林的水质分类方法及系统
EP3665705A1 (en) 2017-08-08 2020-06-17 Fresenius Medical Care Holdings, Inc. Systems and methods for treating and estimating progression of chronic kidney disease
CN107326093B (zh) * 2017-09-04 2020-01-21 东南大学 基于Taqman探针的慢性肾脏病相关基因检测荧光定量PCR一步法试剂盒及其应用
JP7163375B2 (ja) * 2017-09-28 2022-10-31 メタボルン インコーポレーティッド 化合物、試薬、およびそれらの使用
JP7361698B2 (ja) * 2018-01-19 2023-10-16 マース インコーポレーテッド ネコの慢性腎臓疾患のためのバイオマーカー及び分類アルゴリズム
JP2021532344A (ja) * 2018-07-14 2021-11-25 マース インコーポレーテッドMars Incorporated 慢性腎臓病のためのバイオマーカー及びテストモデル
KR20210127945A (ko) * 2019-02-20 2021-10-25 가부시키가이샤 파트너 펌 고상 반응 칩 및 이것을 사용한 측정 방법
US20220265611A1 (en) * 2019-07-26 2022-08-25 Fundació Institut D'investigació Biomèdical De Bellvitge (Idibell) Ergothioneine, s-methyl-ergothioneine, and uses thereof
CN112305089B (zh) * 2019-07-26 2022-04-29 长沙都正生物科技股份有限公司 一种慢性肾病诊断生物标记物及其应用
CN111487338B (zh) * 2020-04-16 2022-06-10 中南大学湘雅二医院 一种与肾功能相关的无创生物标记物及其应用
WO2021232211A1 (zh) * 2020-05-19 2021-11-25 深圳市中医院 诊断肾病的标志物以及诊断方法
CN114910587B (zh) * 2022-05-12 2024-03-19 军科正源(上海)生物医药科技有限公司 一种尿液检测用高效液相-串联质谱分析方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02196787A (ja) 1989-01-25 1990-08-03 Otsuka Pharmaceut Co Ltd シュードウリジン誘導体
JPH0661278B2 (ja) 1990-09-18 1994-08-17 旭化成工業株式会社 ミオイノシトールの高感度定量法および定量用組成物
US5712084A (en) * 1995-09-08 1998-01-27 Research Corporation Technologies, Inc. Donor kidney viability test for improved preservation
CN101377492B (zh) * 2007-08-29 2014-04-23 北京九强生物技术股份有限公司 胱抑素c测定试剂盒
EP2813848A3 (en) * 2008-08-29 2015-03-11 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
US9421330B2 (en) 2008-11-03 2016-08-23 Bayer Healthcare Llc Mitigation of contrast-induced nephropathy
NZ592552A (en) * 2008-11-22 2013-12-20 Astute Medical Inc Methods and compositions for diagnosis and prognosis of renal injury and renal failure
WO2010124269A1 (en) 2009-04-24 2010-10-28 National Center For Genome Resources Methods for diagnosis of sepsis and risk of death
JP5197846B2 (ja) 2009-04-30 2013-05-15 紀陽 田仲 腎疾患重篤度を判定する方法又は装置若しくはその作動方法
EP2440214A4 (en) 2009-06-08 2013-07-31 Quark Pharmaceuticals Inc METHODS OF TREATING CHRONIC RENAL DISEASE
WO2011027573A1 (ja) 2009-09-04 2011-03-10 国立大学法人東北大学 ヒトにおける新たな腎疾患マーカー物質
CA2784889C (en) 2009-12-20 2018-06-19 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
WO2011146683A1 (en) 2010-05-19 2011-11-24 Metabolon, Inc. Methods and reagents for metabolomics and histology in a biological sample and a kit for the same
WO2012017071A1 (en) 2010-08-06 2012-02-09 Pronota N.V. Perlecan as a biomarker for renal dysfunction
JP5916058B2 (ja) 2011-08-26 2016-05-11 国立大学法人東北大学 細胞ストレス状態のバイオマーカー
CN103814295B (zh) 2011-09-14 2016-08-24 巴斯夫欧洲公司 用于评估肾毒性的手段和方法
WO2013048344A1 (en) * 2011-09-29 2013-04-04 National University Of Singapore Urinary metabolomic markers for renal insufficiency
CN105209909B (zh) * 2013-05-14 2019-06-07 梅塔博隆股份有限公司 与肾功能相关的生物标记及其使用方法
EP3491004B1 (en) * 2016-07-28 2021-09-01 Metabolon, Inc. Diagnostic methods, therapeutic agents and uses thereof

Also Published As

Publication number Publication date
AU2014265669B2 (en) 2020-05-14
MX2019005748A (es) 2019-08-12
CA2911204C (en) 2023-03-28
BR112015028253A2 (pt) 2017-07-25
CN105209909A (zh) 2015-12-30
ES2702123T3 (es) 2019-02-27
MX365061B (es) 2019-05-22
CN105209909B (zh) 2019-06-07
CA2911204A1 (en) 2014-11-20
HK1218331A1 (zh) 2017-02-10
CN110196335A (zh) 2019-09-03
US20160116486A1 (en) 2016-04-28
US20200103417A1 (en) 2020-04-02
EP3546940B1 (en) 2021-02-17
JP6595984B2 (ja) 2019-10-23
AU2014265669A1 (en) 2015-12-24
EP3410115A1 (en) 2018-12-05
JP2016520192A (ja) 2016-07-11
EP2997366A4 (en) 2017-04-12
US10539575B2 (en) 2020-01-21
CA3184836A1 (en) 2014-11-20
EP3546940A1 (en) 2019-10-02
EP2997366A1 (en) 2016-03-23
EP2997366B1 (en) 2018-10-10
ES2871823T3 (es) 2021-11-02
WO2014186311A1 (en) 2014-11-20
HK1222905A1 (zh) 2017-07-14

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