BR112015028253A2 - biomarcadores relacionados à função renal e métodos para utilização dos mesmos - Google Patents

biomarcadores relacionados à função renal e métodos para utilização dos mesmos

Info

Publication number
BR112015028253A2
BR112015028253A2 BR112015028253A BR112015028253A BR112015028253A2 BR 112015028253 A2 BR112015028253 A2 BR 112015028253A2 BR 112015028253 A BR112015028253 A BR 112015028253A BR 112015028253 A BR112015028253 A BR 112015028253A BR 112015028253 A2 BR112015028253 A2 BR 112015028253A2
Authority
BR
Brazil
Prior art keywords
renal function
methods
biomarkers
related biomarkers
kidney disease
Prior art date
Application number
BR112015028253A
Other languages
English (en)
Inventor
Kennedy Adam
Edmond Cobb Jeffrey
V Brown Meredith
Perichon Regis
Original Assignee
Metabolon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metabolon Inc filed Critical Metabolon Inc
Publication of BR112015028253A2 publication Critical patent/BR112015028253A2/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/64—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving ketones
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/70—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving creatine or creatinine
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00—Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/34—Genitourinary disorders
    • G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/56—Staging of a disease; Further complications associated with the disease

Abstract

resumo patente de invenção: "biomarcadores relacionados à função renal e métodos para utilização dos mesmos". a presente invenção refere-se a biomarcadores da função renal e métodos para a utilização dos ditos biomarcadores para avaliar a função renal, monitoração da função renal, diagnóstico da lesão renal aguda e diagnóstico de doença renal crônica. também são fornecidos suítes de pequenas entidades de molécula como biomarcadores para a doença renal crônica.
BR112015028253A 2013-05-14 2014-05-13 biomarcadores relacionados à função renal e métodos para utilização dos mesmos BR112015028253A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361822965P 2013-05-14 2013-05-14
PCT/US2014/037762 WO2014186311A1 (en) 2013-05-14 2014-05-13 Biomarkers related to kidney function and methods using the same

Publications (1)

Publication Number Publication Date
BR112015028253A2 true BR112015028253A2 (pt) 2017-07-25

Family

ID=51898805

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015028253A BR112015028253A2 (pt) 2013-05-14 2014-05-13 biomarcadores relacionados à função renal e métodos para utilização dos mesmos

Country Status (11)

Country Link
US (2) US10539575B2 (pt)
EP (3) EP3546940B1 (pt)
JP (1) JP6595984B2 (pt)
CN (2) CN105209909B (pt)
AU (1) AU2014265669B2 (pt)
BR (1) BR112015028253A2 (pt)
CA (2) CA2911204C (pt)
ES (2) ES2702123T3 (pt)
HK (2) HK1218331A1 (pt)
MX (2) MX365061B (pt)
WO (1) WO2014186311A1 (pt)

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US20180003721A1 (en) * 2015-01-15 2018-01-04 Joslin Diabetes Center Metabolite Biomarkers Predictive Of Renal Disease In Diabetic Patients
US11266730B2 (en) 2015-09-29 2022-03-08 The General Hospital Corporation Methods of treating and diagnosing disease using biomarkers for BCG therapy
US20170234874A1 (en) * 2015-10-07 2017-08-17 Clearbridge Biophotonics Pte Ltd. Integrated visual morphology and cell protein expression using resonance-light scattering
CN109563127B (zh) * 2016-07-28 2024-01-05 麦特博隆股份有限公司 化合物、试剂及其用途
EP3552022B1 (en) * 2016-11-25 2021-06-09 Implexion AB Metabolic disorders
WO2018118630A1 (en) 2016-12-19 2018-06-28 Metabolon, Inc. Mass spectrometry assay method for detection and quantitation of kidney function metabolites
CN108956790A (zh) * 2017-05-18 2018-12-07 中国人民解放军第二军医大学第二附属医院 一组氨基酸标志物在急性肾损伤诊断试剂盒中的应用
CN107132266A (zh) * 2017-06-21 2017-09-05 佛山科学技术学院 一种基于随机森林的水质分类方法及系统
US11026625B2 (en) 2017-08-08 2021-06-08 Fresenius Medical Care Holdings, Inc. Systems and methods for treating and estimating progression of chronic kidney disease
CN107326093B (zh) * 2017-09-04 2020-01-21 东南大学 基于Taqman探针的慢性肾脏病相关基因检测荧光定量PCR一步法试剂盒及其应用
JP7163375B2 (ja) * 2017-09-28 2022-10-31 メタボルン インコーポレーティッド 化合物、試薬、およびそれらの使用
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CN112305089B (zh) * 2019-07-26 2022-04-29 长沙都正生物科技股份有限公司 一种慢性肾病诊断生物标记物及其应用
JP7424593B2 (ja) * 2019-07-26 2024-01-30 フンダシオ・インスティトゥート・ディンヴェスティガシオ・ビオメディカ・デ・ベルヴィッチ（イディベル） エルゴチオネイン、ｓ－メチル－エルゴチオネイン、及びそれらの使用
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CN114910587B (zh) * 2022-05-12 2024-03-19 军科正源(上海)生物医药科技有限公司 一种尿液检测用高效液相-串联质谱分析方法

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Also Published As

Publication number Publication date
CA3184836A1 (en) 2014-11-20
AU2014265669B2 (en) 2020-05-14
CN105209909A (zh) 2015-12-30
ES2871823T3 (es) 2021-11-02
MX2015015561A (es) 2016-02-05
US10539575B2 (en) 2020-01-21
CA2911204A1 (en) 2014-11-20
CA2911204C (en) 2023-03-28
MX365061B (es) 2019-05-22
EP2997366B1 (en) 2018-10-10
US20160116486A1 (en) 2016-04-28
US20200103417A1 (en) 2020-04-02
CN105209909B (zh) 2019-06-07
EP2997366A4 (en) 2017-04-12
AU2014265669A1 (en) 2015-12-24
JP2016520192A (ja) 2016-07-11
EP2997366A1 (en) 2016-03-23
ES2702123T3 (es) 2019-02-27
CN110196335A (zh) 2019-09-03
HK1222905A1 (zh) 2017-07-14
HK1218331A1 (zh) 2017-02-10
EP3546940B1 (en) 2021-02-17
WO2014186311A1 (en) 2014-11-20
EP3410115A1 (en) 2018-12-05
JP6595984B2 (ja) 2019-10-23
MX2019005748A (es) 2019-08-12
EP3546940A1 (en) 2019-10-02

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]