DK2900279T3 - Grpr-antagonister til detektering, diagnose og behandling af grpr-positiv cancer - Google Patents

Grpr-antagonister til detektering, diagnose og behandling af grpr-positiv cancer

Info

Publication number
DK2900279T3
DK2900279T3 DK13815181.6T DK13815181T DK2900279T3 DK 2900279 T3 DK2900279 T3 DK 2900279T3 DK 13815181 T DK13815181 T DK 13815181T DK 2900279 T3 DK2900279 T3 DK 2900279T3
Authority
DK
Denmark
Prior art keywords
grpr
diagnosis
detection
treatment
antagonists
Prior art date
Application number
DK13815181.6T
Other languages
English (en)
Inventor
Theodosia Maina-Nock
Berthold Artur Nock
Jong Hendriks Marion De
Original Assignee
Advanced Accelerator Applications Usa Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced Accelerator Applications Usa Inc filed Critical Advanced Accelerator Applications Usa Inc
Application granted granted Critical
Publication of DK2900279T3 publication Critical patent/DK2900279T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/008Peptides; Proteins
DK13815181.6T 2012-09-25 2013-09-25 Grpr-antagonister til detektering, diagnose og behandling af grpr-positiv cancer DK2900279T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261705513P 2012-09-25 2012-09-25
PCT/US2013/061712 WO2014052471A1 (en) 2012-09-25 2013-09-25 Grpr-antagonists for detection, diagnosis and treatment of grpr-positive cancer

Publications (1)

Publication Number Publication Date
DK2900279T3 true DK2900279T3 (da) 2019-09-30

Family

ID=49887190

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13815181.6T DK2900279T3 (da) 2012-09-25 2013-09-25 Grpr-antagonister til detektering, diagnose og behandling af grpr-positiv cancer

Country Status (19)

Country Link
US (6) US9839703B2 (da)
EP (2) EP2900279B1 (da)
JP (4) JP6562838B2 (da)
KR (2) KR102190005B1 (da)
AU (4) AU2013323596C1 (da)
BR (1) BR112015006453B1 (da)
CA (2) CA2886068C (da)
DK (1) DK2900279T3 (da)
ES (1) ES2745635T3 (da)
HR (1) HRP20191620T1 (da)
HU (1) HUE045724T2 (da)
IL (3) IL237844B (da)
LT (1) LT2900279T (da)
MX (1) MX362675B (da)
PL (1) PL2900279T3 (da)
PT (1) PT2900279T (da)
RU (2) RU2019119378A (da)
SI (1) SI2900279T1 (da)
WO (1) WO2014052471A1 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013007660A1 (en) * 2011-07-08 2013-01-17 Biosynthema Inc. Enhanced in vivo targeting of radiolabelled peptides with the means of enzyme inhibitors
PT2900279T (pt) * 2012-09-25 2019-10-14 Advanced Accelerator Applications Usa Inc Antagonistas de grpr para a deteção, diagnóstico e tratamento de cancro positivo para grpr
EP3015462A1 (en) * 2014-10-29 2016-05-04 OctreoPharm Schiences GmbH Enantiopure chelating agents for chelator coupled pharmaceuticals, corresponding preparation method thereof and chelator coupled pharmaceuticals
EP3101012A1 (en) 2015-06-04 2016-12-07 Bayer Pharma Aktiengesellschaft New gadolinium chelate compounds for use in magnetic resonance imaging
WO2018048882A1 (en) 2016-09-06 2018-03-15 The Research Foundation For The State University Of New York Positron imaging tomography imaging agent composition and method for bacterial infection
JP7034160B2 (ja) 2016-11-28 2022-03-11 バイエル・ファルマ・アクティエンゲゼルシャフト 磁気共鳴画像法に使用するための高緩和度ガドリニウムキレート化合物
PT3568205T (pt) 2017-01-12 2023-10-26 Radiomedix Inc Tratamento de células de cancro que sobrexpressam recetores de somatostatina com a utilização de derivados de ocreótido quelado a radioisótopos
CN113195005B (zh) * 2018-10-12 2023-07-21 国际先进加速器应用公司 包含放射性标记的grpr拮抗剂和表面活性剂的药物组合物
WO2021068051A1 (en) * 2018-11-13 2021-04-15 Provincial Health Services Authority Radiolabeled bombesin-derived compounds for in vivo imaging of gastrin-releasing peptide receptor (grpr) and treatment of grpr-related disorders
US11944690B2 (en) 2018-11-23 2024-04-02 Bayer Aktiengesellschaft Formulation of contrast media and process of preparation thereof
JP2022548875A (ja) * 2019-09-16 2022-11-22 ノバルティス アーゲー 安定した濃縮放射性医薬組成物
TW202123975A (zh) * 2019-09-17 2021-07-01 義大利商先進艾斯雷特應用(義大利)公司 放射性標記grpr拮抗劑之方法及其套組
AU2020356262A1 (en) * 2019-09-24 2022-05-05 Novartis Ag Radiolabelled GRPR-antagonist for use as theragnostic
AU2020405585A1 (en) * 2019-12-19 2022-08-11 Technische Universität München Modified GRPR antagonist peptides for imaging and therapy of cancer

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5019647A (en) * 1988-05-24 1991-05-28 Merck & Co., Inc. Gastrin releasing peptide antagonist
US4943561A (en) 1988-11-28 1990-07-24 Merck & Co., Inc. Gastrin releasing peptide antagonist
US5028692A (en) * 1989-04-25 1991-07-02 Merck & Co., Inc. Gastrin releasing peptide antagonist
JPH04502629A (ja) 1989-11-06 1992-05-14 フアルミタリア・カルロ・エルバ・エツセ・エルレ・エルレ 還元不可逆性ボンベシンアンタゴニスト
JPH07505865A (ja) 1992-02-07 1995-06-29 メレルダウファーマスーティカルズ インコーポレイテッド ボンベシンのフェニルアラニン類似体類
US5620955A (en) 1993-06-18 1997-04-15 Peptide Technologies Corporation Bombesin receptor antagonists and uses thereof
EP1033372A4 (en) 1997-11-18 2000-10-04 Chugai Pharmaceutical Co Ltd COMPOSITIONS WITH ANTI-TUMOR ACTIVITY
CA2783275A1 (en) * 2003-07-24 2005-02-03 Bracco Imaging S.P.A. Stable radiopharmaceutical compositions and methods for their preparation
EP2100900A1 (en) * 2008-03-07 2009-09-16 Universitätsspital Basel Bombesin analog peptide antagonist conjugates
KR20140053819A (ko) 2010-11-22 2014-05-08 피라말 이미징 에스에이 방사선요법용 177루테튬-표지 봄베신 유사체
WO2013007660A1 (en) * 2011-07-08 2013-01-17 Biosynthema Inc. Enhanced in vivo targeting of radiolabelled peptides with the means of enzyme inhibitors
PT2900279T (pt) * 2012-09-25 2019-10-14 Advanced Accelerator Applications Usa Inc Antagonistas de grpr para a deteção, diagnóstico e tratamento de cancro positivo para grpr

Also Published As

Publication number Publication date
IL276300A (en) 2020-09-30
SI2900279T1 (sl) 2019-12-31
LT2900279T (lt) 2019-11-11
AU2013323596B2 (en) 2018-03-22
RU2693465C9 (ru) 2020-08-14
KR20200139846A (ko) 2020-12-14
JP2019167365A (ja) 2019-10-03
RU2015115529A (ru) 2016-11-20
CA3114832A1 (en) 2014-04-03
AU2019216714A1 (en) 2019-09-05
JP2021191800A (ja) 2021-12-16
KR102314293B1 (ko) 2021-10-19
MX2015003772A (es) 2015-11-09
PL2900279T3 (pl) 2020-05-18
KR102190005B1 (ko) 2020-12-15
AU2018204513A1 (en) 2018-07-12
AU2013323596C1 (en) 2020-10-15
AU2018204513B2 (en) 2019-05-23
MX362675B (es) 2019-01-30
AU2013323596A1 (en) 2015-04-02
AU2021201914A1 (en) 2021-04-29
RU2693465C2 (ru) 2019-07-03
US9839703B2 (en) 2017-12-12
EP2900279B1 (en) 2019-08-14
KR20150090886A (ko) 2015-08-06
IL237844B (en) 2018-01-31
IL256649B (en) 2020-08-31
RU2019119378A (ru) 2020-10-23
US20220008568A1 (en) 2022-01-13
JP7358430B2 (ja) 2023-10-10
PT2900279T (pt) 2019-10-14
CA2886068C (en) 2021-06-22
US20180133349A1 (en) 2018-05-17
JP2023126440A (ja) 2023-09-07
HUE045724T2 (hu) 2020-01-28
US20210346529A1 (en) 2021-11-11
JP6562838B2 (ja) 2019-08-21
BR112015006453B1 (pt) 2023-10-17
AU2018204513C1 (en) 2020-10-15
US20200009276A1 (en) 2020-01-09
JP6997135B2 (ja) 2022-02-04
HRP20191620T1 (hr) 2019-12-13
CA2886068A1 (en) 2014-04-03
EP2900279A1 (en) 2015-08-05
BR112015006453A2 (da) 2017-09-05
JP2015533119A (ja) 2015-11-19
US20150265732A1 (en) 2015-09-24
ES2745635T3 (es) 2020-03-03
AU2019216714B2 (en) 2021-04-08
EP3536347A1 (en) 2019-09-11
IL256649A (en) 2018-02-28
US11083805B2 (en) 2021-08-10
US20210346528A1 (en) 2021-11-11
WO2014052471A1 (en) 2014-04-03

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