MX365061B - Biomarcadores relacionados a la funcion renal y metodos para usar los mismos. - Google Patents

Biomarcadores relacionados a la funcion renal y metodos para usar los mismos.

Info

Publication number
MX365061B
MX365061B MX2015015561A MX2015015561A MX365061B MX 365061 B MX365061 B MX 365061B MX 2015015561 A MX2015015561 A MX 2015015561A MX 2015015561 A MX2015015561 A MX 2015015561A MX 365061 B MX365061 B MX 365061B
Authority
MX
Mexico
Prior art keywords
kidney function
methods
biomarkers
same
kidney
Prior art date
Application number
MX2015015561A
Other languages
English (en)
Other versions
MX2015015561A (es
Inventor
V Brown Meredith
Perichon Regis
Edmond Cobb Jeffery
Kennedy Adam
Original Assignee
Metabolon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metabolon Inc filed Critical Metabolon Inc
Publication of MX2015015561A publication Critical patent/MX2015015561A/es
Publication of MX365061B publication Critical patent/MX365061B/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/64—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving ketones
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/70—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving creatine or creatinine
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00—Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/34—Genitourinary disorders
    • G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/56—Staging of a disease; Further complications associated with the disease

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Se proporcionan biomarcadores de la función renal y métodos para usar los biomarcadores para evaluar la función renal, monitorear la función renal, diagnosticar lesiones renales agudas, y diagnosticar enfermedades renales crónicas. También se proporcionan modalidades de entidades de moléculas pequeñas como biomarcadores para enfermedades renales crónicas.
MX2015015561A 2013-05-14 2014-05-13 Biomarcadores relacionados a la funcion renal y metodos para usar los mismos. MX365061B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361822965P 2013-05-14 2013-05-14
PCT/US2014/037762 WO2014186311A1 (en) 2013-05-14 2014-05-13 Biomarkers related to kidney function and methods using the same

Publications (2)

Publication Number Publication Date
MX2015015561A MX2015015561A (es) 2016-02-05
MX365061B true MX365061B (es) 2019-05-22

Family

ID=51898805

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2019005748A MX391220B (es) 2013-05-14 2014-05-13 Biomarcadores relacionados a la funcion renal y metodos para usar los mismos.
MX2015015561A MX365061B (es) 2013-05-14 2014-05-13 Biomarcadores relacionados a la funcion renal y metodos para usar los mismos.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2019005748A MX391220B (es) 2013-05-14 2014-05-13 Biomarcadores relacionados a la funcion renal y metodos para usar los mismos.

Country Status (10)

Country Link
US (2) US10539575B2 (es)
EP (3) EP2997366B1 (es)
JP (1) JP6595984B2 (es)
CN (2) CN105209909B (es)
AU (1) AU2014265669B2 (es)
BR (1) BR112015028253A2 (es)
CA (2) CA3184836A1 (es)
ES (2) ES2702123T3 (es)
MX (2) MX391220B (es)
WO (1) WO2014186311A1 (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3184836A1 (en) * 2013-05-14 2014-11-20 Metabolon, Inc. Biomarkers related to kidney function and methods using the same
CN111239415B (zh) 2013-10-17 2024-03-26 综合医院公司 鉴定响应于用于自身免疫性疾病的治疗的受试者的方法以及用于治疗该疾病的组合物
US10254272B2 (en) * 2015-01-09 2019-04-09 Global Genomics Group, LLC Blood based biomarkers for diagnosing atherosclerotic coronary artery disease
WO2016115496A1 (en) * 2015-01-15 2016-07-21 Joslin Diabetes Center Metabolite biomarkers predictive of renal disease in diabetic patients
EP3355914B1 (en) 2015-09-29 2024-03-06 The General Hospital Corporation A composition comprising bcg for reducing cholesterol.
US20170234874A1 (en) * 2015-10-07 2017-08-17 Clearbridge Biophotonics Pte Ltd. Integrated visual morphology and cell protein expression using resonance-light scattering
US12057228B1 (en) 2015-12-30 2024-08-06 Cerner Innovation, Inc. Predicting newly incident chronic kidney disease
AU2017301949B2 (en) * 2016-07-28 2021-09-23 Metabolon, Inc. Compounds, reagents, and uses thereof
EP3552022B1 (en) * 2016-11-25 2021-06-09 Implexion AB Metabolic disorders
WO2018118630A1 (en) 2016-12-19 2018-06-28 Metabolon, Inc. Mass spectrometry assay method for detection and quantitation of kidney function metabolites
CN108956790A (zh) * 2017-05-18 2018-12-07 中国人民解放军第二军医大学第二附属医院 一组氨基酸标志物在急性肾损伤诊断试剂盒中的应用
CN107132266A (zh) * 2017-06-21 2017-09-05 佛山科学技术学院 一种基于随机森林的水质分类方法及系统
EP3665705B1 (en) 2017-08-08 2024-12-18 Fresenius Medical Care Holdings, Inc. Systems and methods for treating and estimating progression of chronic kidney disease
CN107326093B (zh) * 2017-09-04 2020-01-21 东南大学 基于Taqman探针的慢性肾脏病相关基因检测荧光定量PCR一步法试剂盒及其应用
CA3077029A1 (en) * 2017-09-28 2019-04-04 Metabolon, Inc. Compounds, reagents, and uses thereof
CA3089817A1 (en) * 2018-01-19 2019-07-25 Mars, Incorporated Biomarkers and classification algorithms for chronic kidney disease in cats
US20210327589A1 (en) * 2018-07-14 2021-10-21 Mars, Incorporated Biomarkers and test models for chronic kidney disease
WO2020171158A1 (ja) * 2019-02-20 2020-08-27 株式会社パートナーファーム 固相反応チップ及びこれを用いた測定方法
WO2021018774A1 (en) * 2019-07-26 2021-02-04 Fundació Institut D'investigació Biomèdica De Bellvitge (Idibell) Ergothioneine, s-methyl-ergothioneine, and uses thereof
CN112305089B (zh) * 2019-07-26 2022-04-29 长沙都正生物科技股份有限公司 一种慢性肾病诊断生物标记物及其应用
CN111487338B (zh) * 2020-04-16 2022-06-10 中南大学湘雅二医院 一种与肾功能相关的无创生物标记物及其应用
WO2021232211A1 (zh) * 2020-05-19 2021-11-25 深圳市中医院 诊断肾病的标志物以及诊断方法
KR102697110B1 (ko) 2020-12-07 2024-08-22 킴벌리-클라크 월드와이드, 인크. 대사산물을 검출하기 위한 방법 및 소비자 제품
CN114910587B (zh) * 2022-05-12 2024-03-19 军科正源(上海)生物医药科技有限公司 一种尿液检测用高效液相-串联质谱分析方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02196787A (ja) 1989-01-25 1990-08-03 Otsuka Pharmaceut Co Ltd シュードウリジン誘導体
JPH0661278B2 (ja) 1990-09-18 1994-08-17 旭化成工業株式会社 ミオイノシトールの高感度定量法および定量用組成物
US5712084A (en) * 1995-09-08 1998-01-27 Research Corporation Technologies, Inc. Donor kidney viability test for improved preservation
CN101377492B (zh) 2007-08-29 2014-04-23 北京九强生物技术股份有限公司 胱抑素c测定试剂盒
EP2324354B1 (en) * 2008-08-29 2014-07-16 Astute Medical, Inc. Methods for prognosis of acute renal failure
US9421330B2 (en) * 2008-11-03 2016-08-23 Bayer Healthcare Llc Mitigation of contrast-induced nephropathy
CN104034901A (zh) * 2008-11-22 2014-09-10 阿斯图特医药公司 用于诊断和预后肾损伤和肾衰竭的方法和组合物
WO2010124269A1 (en) 2009-04-24 2010-10-28 National Center For Genome Resources Methods for diagnosis of sepsis and risk of death
JP5197846B2 (ja) * 2009-04-30 2013-05-15 紀陽 田仲 腎疾患重篤度を判定する方法又は装置若しくはその作動方法
US8637482B2 (en) * 2009-06-08 2014-01-28 Quark Pharmaceuticals, Inc. Methods for treating chronic kidney disease
JP5757626B2 (ja) 2009-09-04 2015-07-29 国立大学法人東北大学 ヒトにおける新たな腎疾患マーカー物質
KR20120123056A (ko) 2009-12-20 2012-11-07 아스튜트 메디컬 인코포레이티드 신손상 및 신부전을 진단 및 예측하는 방법 및 조성물
WO2011146683A1 (en) * 2010-05-19 2011-11-24 Metabolon, Inc. Methods and reagents for metabolomics and histology in a biological sample and a kit for the same
CA2802273A1 (en) 2010-08-06 2012-02-09 Pronota N.V. Perlecan as a biomarker for renal dysfunction
JP5916058B2 (ja) 2011-08-26 2016-05-11 国立大学法人東北大学 細胞ストレス状態のバイオマーカー
KR20140074293A (ko) 2011-09-14 2014-06-17 바스프 에스이 신장 독성을 평가하기 위한 수단 및 방법
WO2013048344A1 (en) * 2011-09-29 2013-04-04 National University Of Singapore Urinary metabolomic markers for renal insufficiency
CA3184836A1 (en) * 2013-05-14 2014-11-20 Metabolon, Inc. Biomarkers related to kidney function and methods using the same
AU2017301949B2 (en) * 2016-07-28 2021-09-23 Metabolon, Inc. Compounds, reagents, and uses thereof

Also Published As

Publication number Publication date
HK1218331A1 (zh) 2017-02-10
AU2014265669B2 (en) 2020-05-14
EP3546940A1 (en) 2019-10-02
HK1222905A1 (en) 2017-07-14
EP3546940B1 (en) 2021-02-17
WO2014186311A1 (en) 2014-11-20
CN110196335A (zh) 2019-09-03
US20200103417A1 (en) 2020-04-02
CN105209909B (zh) 2019-06-07
US20160116486A1 (en) 2016-04-28
MX2015015561A (es) 2016-02-05
EP2997366A4 (en) 2017-04-12
BR112015028253A2 (pt) 2017-07-25
CN105209909A (zh) 2015-12-30
AU2014265669A1 (en) 2015-12-24
CA2911204C (en) 2023-03-28
MX391220B (es) 2025-03-21
US10539575B2 (en) 2020-01-21
JP6595984B2 (ja) 2019-10-23
JP2016520192A (ja) 2016-07-11
ES2702123T3 (es) 2019-02-27
EP2997366A1 (en) 2016-03-23
EP3410115A1 (en) 2018-12-05
CA3184836A1 (en) 2014-11-20
CA2911204A1 (en) 2014-11-20
MX2019005748A (es) 2019-08-12
ES2871823T3 (es) 2021-11-02
EP2997366B1 (en) 2018-10-10

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