JP6580305B2 - 外用医薬組成物 - Google Patents

外用医薬組成物 Download PDF

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Publication number
JP6580305B2
JP6580305B2 JP2014070678A JP2014070678A JP6580305B2 JP 6580305 B2 JP6580305 B2 JP 6580305B2 JP 2014070678 A JP2014070678 A JP 2014070678A JP 2014070678 A JP2014070678 A JP 2014070678A JP 6580305 B2 JP6580305 B2 JP 6580305B2
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JP
Japan
Prior art keywords
pharmaceutical composition
tocopherol
weight
external
diclofenac
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2014070678A
Other languages
English (en)
Japanese (ja)
Other versions
JP2015189760A (ja
Inventor
和克 阿度
和克 阿度
こずえ 今井
こずえ 今井
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kobayashi Pharmaceutical Co Ltd
Original Assignee
Kobayashi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP2014070678A priority Critical patent/JP6580305B2/ja
Application filed by Kobayashi Pharmaceutical Co Ltd filed Critical Kobayashi Pharmaceutical Co Ltd
Priority to MYPI2016703598A priority patent/MY182059A/en
Priority to SG10201810093PA priority patent/SG10201810093PA/en
Priority to TW104109752A priority patent/TWI712408B/zh
Priority to PCT/JP2015/059323 priority patent/WO2015151990A1/ja
Priority to CN201580028390.6A priority patent/CN106456598B/zh
Priority to SG11201608123VA priority patent/SG11201608123VA/en
Publication of JP2015189760A publication Critical patent/JP2015189760A/ja
Application granted granted Critical
Publication of JP6580305B2 publication Critical patent/JP6580305B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2014070678A 2014-03-30 2014-03-30 外用医薬組成物 Active JP6580305B2 (ja)

Priority Applications (7)

Application Number Priority Date Filing Date Title
JP2014070678A JP6580305B2 (ja) 2014-03-30 2014-03-30 外用医薬組成物
SG10201810093PA SG10201810093PA (en) 2014-03-30 2015-03-26 Pharmaceutical composition for external use
TW104109752A TWI712408B (zh) 2014-03-30 2015-03-26 外用醫藥組成物
PCT/JP2015/059323 WO2015151990A1 (ja) 2014-03-30 2015-03-26 外用医薬組成物
MYPI2016703598A MY182059A (en) 2014-03-30 2015-03-26 Pharmaceutical composition for external use
CN201580028390.6A CN106456598B (zh) 2014-03-30 2015-03-26 外用药物组合物
SG11201608123VA SG11201608123VA (en) 2014-03-30 2015-03-26 Pharmaceutical composition for external use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2014070678A JP6580305B2 (ja) 2014-03-30 2014-03-30 外用医薬組成物

Publications (2)

Publication Number Publication Date
JP2015189760A JP2015189760A (ja) 2015-11-02
JP6580305B2 true JP6580305B2 (ja) 2019-09-25

Family

ID=54240316

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014070678A Active JP6580305B2 (ja) 2014-03-30 2014-03-30 外用医薬組成物

Country Status (6)

Country Link
JP (1) JP6580305B2 (zh)
CN (1) CN106456598B (zh)
MY (1) MY182059A (zh)
SG (2) SG10201810093PA (zh)
TW (1) TWI712408B (zh)
WO (1) WO2015151990A1 (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7086597B2 (ja) * 2017-12-28 2022-06-20 小林製薬株式会社 外用組成物
JP7086596B2 (ja) * 2017-12-28 2022-06-20 小林製薬株式会社 外用組成物

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5976013A (ja) * 1982-10-23 1984-04-28 Toko Yakuhin Kogyo Kk 外用ゲル製剤
JP3044352B2 (ja) * 1989-11-20 2000-05-22 ライオン株式会社 貼付剤
US5350769A (en) * 1990-10-30 1994-09-27 Ss Pharmaceutical Co., Ltd. Antiinflammatory gel preparation
JP3100408B2 (ja) * 1991-03-26 2000-10-16 株式会社資生堂 ジクロフェナックナトリウム含有皮膚外用製剤
JPH11255644A (ja) * 1998-03-09 1999-09-21 Lintec Corp 経皮吸収型解熱消炎鎮痛剤
US7138394B2 (en) * 2002-09-27 2006-11-21 Alpharx Inc. Vehicle for topical delivery of anti-inflammatory compounds
JP4820065B2 (ja) * 2004-05-24 2011-11-24 同仁医薬化工株式会社 消炎鎮痛外用水性液剤
AR051397A1 (es) * 2004-10-21 2007-01-10 Novartis Ag Composicion farmaceutica
CH699814B1 (de) * 2007-05-14 2010-05-14 Mepha Ag Diclofenac zur topischen Anwendung als Spray.
EP2211837B1 (en) * 2007-06-08 2013-11-13 Troikaa Pharmaceuticals Ltd A non-aqueous topical solution of diclofenac and process for preparing the same
CN102292068B (zh) * 2009-01-30 2013-10-09 克迪斯药品有限公司 双氯芬酸、卡马西平和苄达明的透皮递送
JP5421063B2 (ja) * 2009-10-23 2014-02-19 帝國製薬株式会社 ジクロフェナクナトリウム含有水性貼付剤
CN104010635A (zh) * 2011-09-09 2014-08-27 Api起源有限责任公司 包含trpv1选择性激动剂的止痛组合物及其制备和应用
JP6738120B2 (ja) * 2013-03-29 2020-08-12 小林製薬株式会社 外用医薬組成物

Also Published As

Publication number Publication date
CN106456598B (zh) 2020-06-02
JP2015189760A (ja) 2015-11-02
SG11201608123VA (en) 2016-11-29
SG10201810093PA (en) 2018-12-28
WO2015151990A1 (ja) 2015-10-08
CN106456598A (zh) 2017-02-22
MY182059A (en) 2021-01-18
TW201622712A (zh) 2016-07-01
TWI712408B (zh) 2020-12-11

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