JP6554099B2 - ｐ５３変異体を再活性化することの可能なペプチド - Google Patents
ｐ５３変異体を再活性化することの可能なペプチド Download PDFInfo
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4746—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used p53
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
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- A—HUMAN NECESSITIES
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Landscapes
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
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- Toxicology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
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| US201361862977P | 2013-08-07 | 2013-08-07 | |
| US61/862,977 | 2013-08-07 | ||
| PCT/IB2014/063777 WO2015019318A1 (en) | 2013-08-07 | 2014-08-07 | Peptides capable of reactivating p53 mutants |
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| JP2019125644A Division JP2019214573A (ja) | 2013-08-07 | 2019-07-04 | ｐ５３変異体を再活性化することの可能なペプチド |
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| JP2016527891A JP2016527891A (ja) | 2016-09-15 |
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| US (4) | US9856289B2 (OSRAM) |
| EP (1) | EP3030571B1 (OSRAM) |
| JP (2) | JP6554099B2 (OSRAM) |
| CN (1) | CN105579464B (OSRAM) |
| AU (2) | AU2016200713B2 (OSRAM) |
| BR (1) | BR112016002721A2 (OSRAM) |
| CA (1) | CA2920147C (OSRAM) |
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| HU (1) | HUE049292T2 (OSRAM) |
| IL (2) | IL243944B (OSRAM) |
| RU (2) | RU2721423C2 (OSRAM) |
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| WO2015019318A1 (en) | 2013-08-07 | 2015-02-12 | Yeda Research And Development Co. Ltd. | Peptides capable of reactivating p53 mutants |
| CN105112377B (zh) * | 2015-09-25 | 2018-10-30 | 福州迈新生物技术开发有限公司 | 一株分泌抗p53单克隆抗体的杂交瘤细胞株及其应用 |
| CA3012302A1 (en) * | 2016-02-04 | 2017-08-10 | Yeda Research And Development Co. Ltd. | Peptides and use of same in the treatment of diseases, disorders or conditions associated with a mutant p53 |
| US20220251159A1 (en) * | 2016-02-04 | 2022-08-11 | Yeda Research And Development Co., Ltd | Peptides and use of same in the treatment of diseases, disroders or conditions associated with a mutant p53 |
| CR20200170A (es) * | 2017-09-29 | 2020-11-23 | Us Health | Receptores de células t que reconocen p53 mutado |
| PH12020550788A1 (en) | 2017-12-07 | 2021-04-19 | Reven Llc | Compositions and methods for the treatment of metabolic conditions |
| WO2019116376A1 (en) * | 2017-12-17 | 2019-06-20 | Yeda Research And Development Co. Ltd. | Cop9 signalosome (csn) complex modulators and uses thereof |
| WO2019134650A1 (en) * | 2018-01-02 | 2019-07-11 | Rui Jin Hospital, Shanghai Jiao Tong University School Of Medicine | Mp53 rescue compounds and methods of treating a p53 disorder |
| WO2019134070A1 (en) * | 2018-01-02 | 2019-07-11 | Rui Jin Hospital, Shanghai Jiao Tong University School Of Medicine | Panda as novel therapeutic |
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| US6184205B1 (en) | 1994-07-22 | 2001-02-06 | University Of North Carolina At Chapel Hill | GRB2 SH3 binding peptides and methods of isolating and using same |
| US6169073B1 (en) * | 1995-02-16 | 2001-01-02 | Bayer Corporation | Peptides and peptidomimetics with structural similarity to human p53 that activate p53 function |
| US5877282A (en) | 1996-09-20 | 1999-03-02 | Bristol-Myers Squibb Company | Peptide inhibitors of nuclear protein translocation having nuclear localization sequences and methods of use thereof |
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