CA2920147C - Peptides capable of reactivating p53 mutants - Google Patents
Peptides capable of reactivating p53 mutants Download PDFInfo
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- CA2920147C CA2920147C CA2920147A CA2920147A CA2920147C CA 2920147 C CA2920147 C CA 2920147C CA 2920147 A CA2920147 A CA 2920147A CA 2920147 A CA2920147 A CA 2920147A CA 2920147 C CA2920147 C CA 2920147C
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- Biophysics (AREA)
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| US201361862977P | 2013-08-07 | 2013-08-07 | |
| US61/862,977 | 2013-08-07 | ||
| PCT/IB2014/063777 WO2015019318A1 (en) | 2013-08-07 | 2014-08-07 | Peptides capable of reactivating p53 mutants |
Publications (2)
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| CA2920147A1 CA2920147A1 (en) | 2015-02-12 |
| CA2920147C true CA2920147C (en) | 2022-09-20 |
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| CA2920147A Active CA2920147C (en) | 2013-08-07 | 2014-08-07 | Peptides capable of reactivating p53 mutants |
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| EP (1) | EP3030571B1 (OSRAM) |
| JP (2) | JP6554099B2 (OSRAM) |
| CN (1) | CN105579464B (OSRAM) |
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| IL (2) | IL243944B (OSRAM) |
| RU (2) | RU2721423C2 (OSRAM) |
| WO (1) | WO2015019318A1 (OSRAM) |
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| JP6554099B2 (ja) | 2013-08-07 | 2019-07-31 | イェダ リサーチ アンド ディベロップメント カンパニー リミテッドＹｅｄａ Ｒｅｓｅａｒｃｈ Ａｎｄ Ｄｅｖｅｌｏｐｍｅｎｔ Ｃｏ．Ｌｔｄ． | ｐ５３変異体を再活性化することの可能なペプチド |
| CN105112377B (zh) * | 2015-09-25 | 2018-10-30 | 福州迈新生物技术开发有限公司 | 一株分泌抗p53单克隆抗体的杂交瘤细胞株及其应用 |
| RU2762089C2 (ru) * | 2016-02-04 | 2021-12-15 | Иеда Рисеч Энд Девелопмент Ко. Лтд. | ПЕПТИДЫ И ИХ ПРИМЕНЕНИЕ В ЛЕЧЕНИИ ЗАБОЛЕВАНИЙ, НАРУШЕНИЙ ИЛИ СОСТОЯНИЙ, АССОЦИИРОВАННЫХ С МУТАНТНЫМ р53 |
| US20220251159A1 (en) * | 2016-02-04 | 2022-08-11 | Yeda Research And Development Co., Ltd | Peptides and use of same in the treatment of diseases, disroders or conditions associated with a mutant p53 |
| FI3688027T3 (fi) | 2017-09-29 | 2025-12-09 | Us Health | Mutatoidun p53:n tunnistavia t-solureseptoreita |
| CR20200291A (es) | 2017-12-07 | 2020-11-18 | Reven Ip Holdco Llc | Composiciones y métodos para el tratamiento de enfermedades metabólicas |
| EP3723785A1 (en) * | 2017-12-17 | 2020-10-21 | Yeda Research and Development Co. Ltd | Cop9 signalosome (csn) complex modulators and uses thereof |
| WO2019134650A1 (en) * | 2018-01-02 | 2019-07-11 | Rui Jin Hospital, Shanghai Jiao Tong University School Of Medicine | Mp53 rescue compounds and methods of treating a p53 disorder |
| WO2019134070A1 (en) * | 2018-01-02 | 2019-07-11 | Rui Jin Hospital, Shanghai Jiao Tong University School Of Medicine | Panda as novel therapeutic |
| AR120059A1 (es) * | 2019-06-12 | 2022-02-02 | Reven Ip Holdco Llc | Métodos y composiciones para mejorar resultados de pacientes con cáncer |
| JP7402026B2 (ja) | 2019-11-27 | 2023-12-20 | 株式会社小松製作所 | 作業機械の制御システム、作業機械、作業機械の制御方法 |
| EP4121441A1 (en) | 2020-03-16 | 2023-01-25 | Yeda Research and Development Co. Ltd | Peptide analogs and use of same in treating diseases, disorders or conditions associated with a mutant p53 protein |
| CN111574591B (zh) * | 2020-04-29 | 2021-09-21 | 西安交通大学医学院第一附属医院 | 一种多肽及其合成方法 |
| CN111686127B (zh) * | 2020-06-04 | 2022-02-15 | 华南理工大学 | 锌铁纳米材料在降解突变p53蛋白中的应用 |
| CN113750246B (zh) * | 2020-06-04 | 2023-12-05 | 华南理工大学 | ZIF-8纳米材料在降解广谱突变p53蛋白中的应用 |
| WO2021262483A1 (en) * | 2020-06-24 | 2021-12-30 | Pmv Pharmaceuticals, Inc. | METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION |
| JP2024501840A (ja) * | 2020-12-21 | 2024-01-16 | アラウヌス バイオサイエンシズ， インコーポレイテッド | ペプチダーゼ切断可能基質およびその同定方法ならびにその使用方法 |
| CN112921032A (zh) * | 2020-12-29 | 2021-06-08 | 苏州中科先进技术研究院有限公司 | 一种引物对、探针、试剂盒及其使用方法 |
| CN115466786A (zh) * | 2021-06-11 | 2022-12-13 | 上海交通大学医学院附属瑞金医院 | 一种筛选适合用p53复活药物治疗p53异常相关疾病病人的方法 |
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| US5294605A (en) | 1990-07-19 | 1994-03-15 | The Scripps Research Institute | Amphiphilic peptide compositions and analogues thereof |
| US5614393A (en) * | 1991-10-10 | 1997-03-25 | Rhone-Poulenc Agrochimie | Production of γ-linolenic acid by a Δ6-desaturase |
| US5969120A (en) * | 1993-09-03 | 1999-10-19 | Research Development Foundation | Mutants of the RB and P53 genes |
| US6184205B1 (en) | 1994-07-22 | 2001-02-06 | University Of North Carolina At Chapel Hill | GRB2 SH3 binding peptides and methods of isolating and using same |
| US6169073B1 (en) * | 1995-02-16 | 2001-01-02 | Bayer Corporation | Peptides and peptidomimetics with structural similarity to human p53 that activate p53 function |
| US5877282A (en) | 1996-09-20 | 1999-03-02 | Bristol-Myers Squibb Company | Peptide inhibitors of nuclear protein translocation having nuclear localization sequences and methods of use thereof |
| AU7238098A (en) * | 1997-05-15 | 1998-12-08 | Kyowa Hakko Kogyo Co. Ltd. | Peptides having cyclic structures and exerting p53 protein activty-restoring effect on p53 protein mutants |
| US20030224379A1 (en) * | 2000-01-21 | 2003-12-04 | Tang Y. Tom | Novel nucleic acids and polypeptides |
| WO2002072600A2 (en) | 2001-01-26 | 2002-09-19 | Inhibitex, Inc. | Monoclonal antibodies to the clfa protein and method of use in treating or preventing infections |
| EP1472276A4 (en) * | 2001-02-28 | 2007-05-09 | Keith M Skubitz | PEPTIDES OF SMALL SIZE CAPACITY TO MODULATE THE FUNCTION OF THE MEMBERS OF THE FAMILY OF CD66 (CEACAM) |
| AU2003205830A1 (en) * | 2002-01-23 | 2003-09-02 | Mohamed Raafat El-Gewely | Molecular libraries |
| US7361747B2 (en) * | 2003-05-22 | 2008-04-22 | The University Of Hong Kong | Isolation and characterization of the precursor virus of human SARS virus: SARS-associated corona virus-like virus |
| EP1957045A2 (en) * | 2005-03-14 | 2008-08-20 | Board of Regents, The University of Texas System | Bioactive fus1 peptides and nanoprticle-polypeptide complexes |
| US8877201B2 (en) * | 2007-10-25 | 2014-11-04 | Wake Forest University Health Sciences | Bordetella outer-membrane protein antigens and methods of making and using the same |
| EP2268658B1 (en) * | 2008-03-13 | 2015-12-09 | Universita'Degli Studi di Trieste | Peptides and aptamers thereof as specific modulators of mutant p53 function |
| US8287845B2 (en) * | 2008-12-18 | 2012-10-16 | E I Du Pont De Nemours And Company | Hair-binding peptides |
| US9517252B2 (en) * | 2011-09-09 | 2016-12-13 | Agency For Science, Technology And Research | p53 activating peptides |
| EP2771349B1 (en) * | 2011-09-16 | 2020-02-26 | Iogenetics, LLC. | Bioinformatic processes for determination of peptide binding |
| JP6306593B2 (ja) * | 2012-09-13 | 2018-04-04 | ユニベルシテ ドゥ ジュネーブ | 細胞透過性ペプチド |
| JP6554099B2 (ja) | 2013-08-07 | 2019-07-31 | イェダ リサーチ アンド ディベロップメント カンパニー リミテッドＹｅｄａ Ｒｅｓｅａｒｃｈ Ａｎｄ Ｄｅｖｅｌｏｐｍｅｎｔ Ｃｏ．Ｌｔｄ． | ｐ５３変異体を再活性化することの可能なペプチド |
| RU2762089C2 (ru) | 2016-02-04 | 2021-12-15 | Иеда Рисеч Энд Девелопмент Ко. Лтд. | ПЕПТИДЫ И ИХ ПРИМЕНЕНИЕ В ЛЕЧЕНИИ ЗАБОЛЕВАНИЙ, НАРУШЕНИЙ ИЛИ СОСТОЯНИЙ, АССОЦИИРОВАННЫХ С МУТАНТНЫМ р53 |
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2014
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- 2014-08-07 RU RU2019119609A patent/RU2721423C2/ru active
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- 2014-08-07 HU HUE14834903A patent/HUE049292T2/hu unknown
- 2014-08-07 BR BR112016002721-3A patent/BR112016002721A2/pt not_active Application Discontinuation
- 2014-08-07 RU RU2016106583A patent/RU2693487C2/ru active
- 2014-08-07 CA CA2920147A patent/CA2920147C/en active Active
- 2014-08-07 EP EP14834903.8A patent/EP3030571B1/en active Active
- 2014-08-07 CN CN201480053550.8A patent/CN105579464B/zh not_active Expired - Fee Related
- 2014-08-07 WO PCT/IB2014/063777 patent/WO2015019318A1/en not_active Ceased
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2016
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- 2016-02-04 US US15/015,208 patent/US9856289B2/en active Active
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2017
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