JP6469610B2 - 吸入器 - Google Patents
吸入器 Download PDFInfo
- Publication number
- JP6469610B2 JP6469610B2 JP2016096893A JP2016096893A JP6469610B2 JP 6469610 B2 JP6469610 B2 JP 6469610B2 JP 2016096893 A JP2016096893 A JP 2016096893A JP 2016096893 A JP2016096893 A JP 2016096893A JP 6469610 B2 JP6469610 B2 JP 6469610B2
- Authority
- JP
- Japan
- Prior art keywords
- chamber
- dosing
- inhaler
- drug
- metering
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
- A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
- A61M15/0051—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a tape, e.g. strips
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
- A61M15/001—Details of inhalators; Constructional features thereof with means for agitating the medicament using ultrasonic means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0043—Non-destructive separation of the package, e.g. peeling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
- A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
- A61M15/005—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a cylindrical surface
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
- A61M15/0053—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type or way of disposal
- A61M15/0055—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type or way of disposal the used dosages being coiled
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0085—Inhalators using ultrasonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
- A61M2016/0018—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
- A61M2016/0021—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with a proportional output signal, e.g. from a thermistor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/02—Gases
- A61M2202/0266—Nitrogen (N)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/062—Desiccants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0272—Electro-active or magneto-active materials
- A61M2205/0294—Piezoelectric materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/12—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/82—Internal energy supply devices
- A61M2205/8206—Internal energy supply devices battery-operated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2250/00—Specially adapted for animals
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Anesthesiology (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Medicinal Preparation (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Description
12 個別の投薬コンパートメント
15 フィルム、泊、またはテープ
20 鞘
21 充填アクセス・ポートホール
22 投薬ポートホール
30 投薬チャンバ
32 投薬孔
40 フロー・チャンネル
50 振動発生デバイス
52 動力源
60 投薬リング
70 リング鞘
71 充填アクセス・ポートホール
72 投薬ポートホール
101 吸入器
105 個別の投与量
110 ハウジング
111 振動発生デバイス
112 バッテリ
113 モータ
116 空気取り入れ口
117 圧力センサ
119 oリング
120 カートリッジ
121 エーロゾル・チャンバ
122 膜
123 フロー・チャンネル
124 フロー・チャンネル
125 マウスピース
130 ブリスタ・ストリップ
131 ブリスタ
133 支持体
134 凹部
135 箔、フィルム、またはテープ
140 送りデバイス
141 取り除きデバイス
142 ブリスタ検出スイッチ
143 ギア
144 ギア
145 巻取りスプール
148 パイロット・ループ
150 開放されたエリア
201 医薬品物質
210 リザーバ
211 ピストン
212 圧縮ばね
220 計量ドラム
222 計量凹み
225 計量ドア、第1の計量ドア
226 計量ドア、第2の計量ドア
230 鞘
231 充填アクセス・ポートホール
232 投薬ポートホール
240 投薬チャンバ
250 フロー・チャンネル
330 組み合わせリザーバおよび投薬チャンバ
336 チャンバ・シール
340 フロー・チャンネル
344 振動発生デバイス
352 動力源
360 窒素ライン
Claims (5)
- 人または患者の気道に医薬品を引渡すための吸入器であって、
振動発生デバイスと、モータあるいは機械的前進メカニズムとが入るハウジングと、
前記ハウジングと調和して作用を及ぼすべく形成された取り外し可能なカートリッジであって、ループを形成するカートリッジとを包含し、前記取り外し可能なカートリッジが、さらに、
前記カートリッジの前記ループ内に配された、個別の投与量の医薬品を入れる複数のブリスタを有するストリップと、
フロー・チャンネルと、
前記フロー・チャンネルに接続されるように配置された空気取り入れ口と、
前記フロー・チャンネルに接続されるエーロゾル・チャンバであって、前記振動発生デバイスと接触するように配置された膜は前記エーロゾル・チャンバの壁を形成し、前記エーロゾル・チャンバが、前記医薬品の塊を解くための共振チャンバを形成する前記エーロゾル・チャンバと、
前記医薬品を前記患者に引渡すための前記フロー・チャンネルに接続されたマウスピースと、
前記ストリップを前記エーロゾル・チャンバに関して進ませるデバイスと、
前記エーロゾル・チャンバ近傍の単一のブリスタを開放するためのデバイスであって、前記医薬品の単回分の投与量が前記エーロゾル・チャンバに引渡される前記デバイスと、を包含し、
それによって、前記振動発生デバイスが前記エーロゾル・チャンバと調和して作用を及ぼす、吸入器。 - 前記ハウジングは、さらに、前記空気取り入れ口の中、あるいは近くに位置する圧力センサを包含する、請求項1に記載の吸入器。
- 前記ストリップを前進させるデバイスは、前記ハウジング内に包含される前記モータあるいは少なくとも1つの機械的前進メカニズムによって駆動される、請求項1に記載の吸入器。
- 前記振動発生デバイスは、圧電デバイスである、請求項1に記載の吸入器。
- 前記医薬品が粉末形式である、請求項1に記載の吸入器。
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29240310P | 2010-01-05 | 2010-01-05 | |
US29240110P | 2010-01-05 | 2010-01-05 | |
US29240410P | 2010-01-05 | 2010-01-05 | |
US61/292,403 | 2010-01-05 | ||
US61/292,404 | 2010-01-05 | ||
US61/292,401 | 2010-01-05 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012548100A Division JP6017961B2 (ja) | 2010-01-05 | 2011-01-05 | 吸入デバイスおよび方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2016165510A JP2016165510A (ja) | 2016-09-15 |
JP6469610B2 true JP6469610B2 (ja) | 2019-02-13 |
Family
ID=44223979
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012548100A Expired - Fee Related JP6017961B2 (ja) | 2010-01-05 | 2011-01-05 | 吸入デバイスおよび方法 |
JP2014210159A Expired - Fee Related JP6087887B2 (ja) | 2010-01-05 | 2014-10-14 | 吸入器 |
JP2015246356A Expired - Fee Related JP6283344B2 (ja) | 2010-01-05 | 2015-12-17 | 吸入器 |
JP2016096893A Expired - Fee Related JP6469610B2 (ja) | 2010-01-05 | 2016-05-13 | 吸入器 |
Family Applications Before (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012548100A Expired - Fee Related JP6017961B2 (ja) | 2010-01-05 | 2011-01-05 | 吸入デバイスおよび方法 |
JP2014210159A Expired - Fee Related JP6087887B2 (ja) | 2010-01-05 | 2014-10-14 | 吸入器 |
JP2015246356A Expired - Fee Related JP6283344B2 (ja) | 2010-01-05 | 2015-12-17 | 吸入器 |
Country Status (11)
Country | Link |
---|---|
US (3) | US8991390B2 (ja) |
EP (2) | EP3431128A1 (ja) |
JP (4) | JP6017961B2 (ja) |
CN (3) | CN105381524A (ja) |
CA (1) | CA2784041C (ja) |
ES (1) | ES2702753T3 (ja) |
HK (1) | HK1221184A1 (ja) |
MY (1) | MY187036A (ja) |
PH (2) | PH12014501462A1 (ja) |
TW (1) | TWI589313B (ja) |
WO (1) | WO2011085022A1 (ja) |
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CA2784041C (en) | 2010-01-05 | 2017-11-07 | Microdose Therapeutx, Inc. | Inhalation device and method |
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JP2021513901A (ja) * | 2018-02-23 | 2021-06-03 | マイクロドース セラピューテクス,インコーポレイテッド | 吸入器およびその使用方法 |
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