JP6433785B2 - トランス−クロミフェン代謝物およびその使用 - Google Patents
トランス−クロミフェン代謝物およびその使用 Download PDFInfo
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- JP6433785B2 JP6433785B2 JP2014524097A JP2014524097A JP6433785B2 JP 6433785 B2 JP6433785 B2 JP 6433785B2 JP 2014524097 A JP2014524097 A JP 2014524097A JP 2014524097 A JP2014524097 A JP 2014524097A JP 6433785 B2 JP6433785 B2 JP 6433785B2
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- clomiphene
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- metabolite
- administration
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- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
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- C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
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| UA113291C2 (xx) | 2011-08-04 | 2017-01-10 | Метаболіти транскломіфену і їх застосування | |
| EP2854763B1 (en) | 2012-05-31 | 2018-09-26 | Repros Therapeutics Inc. | Formulations for vaginal delivery of antiprogestins |
| JP6343619B2 (ja) | 2012-11-02 | 2018-06-13 | レプロス セラピューティクス インコーポレイティド | プロゲステロン依存性病態を処置する方法およびその組成物 |
| WO2014070523A1 (en) * | 2012-11-02 | 2014-05-08 | Repros Therapeutics Inc. | Trans-clomiphene for use in cancer therapy |
| WO2017123577A1 (en) * | 2016-01-12 | 2017-07-20 | Repros Therapeutics Inc. | Trans-clomiphene and progesterone receptor antagonist combination therapy for treating hormone-dependent conditions |
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| US9981906B2 (en) | 2018-05-29 |
| SG10201606425WA (en) | 2016-09-29 |
| EP3351527A1 (en) | 2018-07-25 |
| CN103702975B (zh) | 2016-03-16 |
| CL2014000268A1 (es) | 2014-11-14 |
| UA113291C2 (xx) | 2017-01-10 |
| NI201400008A (es) | 2015-12-10 |
| MX355316B (es) | 2018-04-16 |
| BR112014000908A2 (pt) | 2017-02-21 |
| HK1196349A1 (zh) | 2014-12-12 |
| CR20140124A (es) | 2014-05-13 |
| EP2744777A1 (en) | 2014-06-25 |
| NZ621892A (en) | 2016-03-31 |
| JP2014529584A (ja) | 2014-11-13 |
| ZA201400406B (en) | 2014-11-26 |
| PH12014500144A1 (en) | 2014-02-24 |
| AU2017204171A1 (en) | 2017-07-13 |
| AU2012289964B2 (en) | 2017-03-23 |
| AU2012289964A1 (en) | 2014-01-30 |
| WO2013020017A1 (en) | 2013-02-07 |
| MY191802A (en) | 2022-07-15 |
| JP2019023210A (ja) | 2019-02-14 |
| IL230287B (en) | 2019-07-31 |
| KR20140054110A (ko) | 2014-05-08 |
| CO6862154A2 (es) | 2014-02-10 |
| EA201490416A1 (ru) | 2014-11-28 |
| CA2841572C (en) | 2020-10-13 |
| MY170718A (en) | 2019-08-27 |
| CA2841572A1 (en) | 2013-02-07 |
| MX2014000825A (es) | 2014-02-27 |
| IL230287A0 (en) | 2014-03-06 |
| CN103702975A (zh) | 2014-04-02 |
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