JP6433482B2 - 認知機能を改善するための方法および組成物 - Google Patents
認知機能を改善するための方法および組成物 Download PDFInfo
- Publication number
- JP6433482B2 JP6433482B2 JP2016503074A JP2016503074A JP6433482B2 JP 6433482 B2 JP6433482 B2 JP 6433482B2 JP 2016503074 A JP2016503074 A JP 2016503074A JP 2016503074 A JP2016503074 A JP 2016503074A JP 6433482 B2 JP6433482 B2 JP 6433482B2
- Authority
- JP
- Japan
- Prior art keywords
- oxo
- butanamide
- pharmaceutically acceptable
- cognitive
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- JUPNUOIZFNVFOB-UHFFFAOYSA-O CN(C(C1)=O)c(cc2)c1cc2[OH2+] Chemical compound CN(C(C1)=O)c(cc2)c1cc2[OH2+] JUPNUOIZFNVFOB-UHFFFAOYSA-O 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Emergency Medicine (AREA)
- Addiction (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361800191P | 2013-03-15 | 2013-03-15 | |
| US61/800,191 | 2013-03-15 | ||
| PCT/US2014/029362 WO2014144801A1 (en) | 2013-03-15 | 2014-03-14 | Methods and compositions for improving cognitive function |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018101373A Division JP6808679B2 (ja) | 2013-03-15 | 2018-05-28 | 認知機能を改善するための方法および組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016514688A JP2016514688A (ja) | 2016-05-23 |
| JP2016514688A5 JP2016514688A5 (enExample) | 2017-04-20 |
| JP6433482B2 true JP6433482B2 (ja) | 2018-12-05 |
Family
ID=51537797
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016503074A Active JP6433482B2 (ja) | 2013-03-15 | 2014-03-14 | 認知機能を改善するための方法および組成物 |
| JP2018101373A Active JP6808679B2 (ja) | 2013-03-15 | 2018-05-28 | 認知機能を改善するための方法および組成物 |
| JP2019144290A Active JP7084632B2 (ja) | 2013-03-15 | 2019-08-06 | 認知機能を改善するための方法および組成物 |
| JP2020207747A Pending JP2021046438A (ja) | 2013-03-15 | 2020-12-15 | 認知機能を改善するための方法および組成物 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018101373A Active JP6808679B2 (ja) | 2013-03-15 | 2018-05-28 | 認知機能を改善するための方法および組成物 |
| JP2019144290A Active JP7084632B2 (ja) | 2013-03-15 | 2019-08-06 | 認知機能を改善するための方法および組成物 |
| JP2020207747A Pending JP2021046438A (ja) | 2013-03-15 | 2020-12-15 | 認知機能を改善するための方法および組成物 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US11160785B2 (enExample) |
| EP (1) | EP2968220B1 (enExample) |
| JP (4) | JP6433482B2 (enExample) |
| CN (1) | CN105142623A (enExample) |
| AU (3) | AU2014228512A1 (enExample) |
| CA (1) | CA2904767C (enExample) |
| DK (1) | DK2968220T3 (enExample) |
| ES (1) | ES2881081T3 (enExample) |
| HK (1) | HK1218623A1 (enExample) |
| WO (1) | WO2014144801A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9212390B2 (en) * | 2010-04-30 | 2015-12-15 | Exiqon A/S | In situ hybridization method and buffer |
| EP3610890A1 (en) | 2012-11-14 | 2020-02-19 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
| WO2014144663A1 (en) | 2013-03-15 | 2014-09-18 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
| RU2578446C1 (ru) * | 2014-12-15 | 2016-03-27 | государственное бюджетное образовательное учреждение высшего профессионального образования "Пермский государственный медицинский университет имени академика Е.А. Вагнера" Министерства здравоохранения Российской Федерации | Способ активации когнитивных функций у лабораторных животных |
| MA50634A (fr) * | 2015-05-22 | 2021-04-28 | Agenebio Inc | Compositions pharmaceutiques à libération prolongée comportant du lévétiracétam |
| NZ738682A (en) | 2015-05-22 | 2022-01-28 | Agenebio Inc | Extended release pharmaceutical compositions of levetiracetam |
| KR102523237B1 (ko) | 2016-08-03 | 2023-04-18 | 유니버시티 오브 사우스 플로리다 | 신경 장애의 치료를 위한 리일린 조성물 |
| CN111172274B (zh) * | 2020-01-22 | 2021-10-15 | 清华大学 | Synaptotagmin-7在双向情感障碍诊断和治疗中的用途 |
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| JP6808679B2 (ja) | 2021-01-06 |
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| US20160271108A1 (en) | 2016-09-22 |
| CA2904767C (en) | 2022-06-21 |
| AU2019201994A1 (en) | 2019-04-18 |
| US11160785B2 (en) | 2021-11-02 |
| DK2968220T3 (da) | 2021-06-14 |
| CN105142623A (zh) | 2015-12-09 |
| HK1220364A1 (zh) | 2017-05-05 |
| JP2021046438A (ja) | 2021-03-25 |
| AU2014228512A1 (en) | 2015-10-01 |
| AU2020210168A1 (en) | 2020-08-13 |
| HK1218623A1 (zh) | 2017-03-03 |
| EP2968220A1 (en) | 2016-01-20 |
| ES2881081T3 (es) | 2021-11-26 |
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