CA2904767C - Methods and compositions for improving cognitive function - Google Patents
Methods and compositions for improving cognitive function Download PDFInfo
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- CA2904767C CA2904767C CA2904767A CA2904767A CA2904767C CA 2904767 C CA2904767 C CA 2904767C CA 2904767 A CA2904767 A CA 2904767A CA 2904767 A CA2904767 A CA 2904767A CA 2904767 C CA2904767 C CA 2904767C
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Landscapes
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| JP6440625B2 (ja) | 2012-11-14 | 2018-12-19 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 精神分裂病を処置するための方法および組成物 |
| WO2014144663A1 (en) | 2013-03-15 | 2014-09-18 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
| RU2578446C1 (ru) * | 2014-12-15 | 2016-03-27 | государственное бюджетное образовательное учреждение высшего профессионального образования "Пермский государственный медицинский университет имени академика Е.А. Вагнера" Министерства здравоохранения Российской Федерации | Способ активации когнитивных функций у лабораторных животных |
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| ES2747993T3 (es) * | 2015-05-22 | 2020-03-12 | Agenebio Inc | Composiciones farmacéuticas de liberación prolongada de levetiracetam |
| CN111172274B (zh) * | 2020-01-22 | 2021-10-15 | 清华大学 | Synaptotagmin-7在双向情感障碍诊断和治疗中的用途 |
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| GB1309692A (en) | 1970-02-13 | 1973-03-14 | Ucb Sa | N-substituted lactams |
| GB1039113A (en) | 1964-08-06 | 1966-08-17 | Ucb Sa | New n-substituted lactams |
| JP2000319257A (ja) | 1969-01-06 | 2000-11-21 | Eisai Co Ltd | 1−ベンジル−4−[(5,6−ジメトキシ−2−フルオロ−1−インダノン)−2−イル]メチルピペリジン |
| IT1045043B (it) | 1975-08-13 | 1980-04-21 | Isf Spa | Derivati pirrolidinici |
| IT1075280B (it) | 1977-02-11 | 1985-04-22 | Isf Spa | Procedimento per la preparazione di derivati pirrolidinici |
| BE864269A (fr) | 1977-03-03 | 1978-06-16 | Parke Davis & Co | Nouveaux n-(aminoalkyl substitue)-2-oxo-1-pyrrolidine-acetamides et procedes pour les produire |
| ATE27T1 (de) | 1978-05-08 | 1981-04-15 | Ucb Sa | Lactam-n-essigsaeuren und ihre amide, verfahren zu ihrer herstellung und heilmittel, die sie enthalten |
| US4654370A (en) | 1979-03-12 | 1987-03-31 | Abbott Laboratories | Glyceryl valproates |
| US4372960A (en) | 1980-12-12 | 1983-02-08 | Warner-Lambert Company | Quaternary derivatives of N-(substituted-aminoalkyl)-2-oxo-1-pyrrolidine-acetamides as cognition activators |
| FR2515179A1 (fr) | 1981-07-24 | 1983-04-29 | Hoffmann La Roche | Derives de pyrrolidine, leur procede de preparation, les intermediaires pour leur synthese et leur application therapeutique |
| IL67623A (en) | 1983-01-05 | 1984-09-30 | Teva Pharma | 1'-ethoxycarbonyloxyethyl ester of valproic acid,its preparation and pharmaceutical compositions containing it |
| IL72381A (en) | 1983-07-20 | 1988-03-31 | Sanofi Sa | Pharmaceutical composition based on valproic acid |
| US4558070A (en) | 1983-10-26 | 1985-12-10 | Abbott Laboratories | Acid salts of valproic acid |
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| GB8412358D0 (en) | 1984-05-15 | 1984-06-20 | Ucb Sa | Pharmaceutical composition |
| US4668687A (en) | 1984-07-23 | 1987-05-26 | Bristol-Myers Company | Psychogeriatric 1-(2-pyrimidinyl)piperazinyl derivatives of 1-pyrrolidin-2-ones |
| US4913906B1 (en) | 1985-02-28 | 2000-06-06 | Yissum Res Dev Co | Controlled release dosage form of valproic acid |
| IL74497A (en) | 1985-03-05 | 1990-02-09 | Proterra Ag | Pharmaceutical compositions containing phenyl carbamate derivatives and certain phenyl carbamate derivatives |
| JPS6222785A (ja) | 1985-07-23 | 1987-01-30 | Sanwa Kagaku Kenkyusho:Kk | 新規な2−オキソピロリジン化合物及びその塩、その製法並びにこれらを有効成分とする脳機能障害の予防及び治療剤 |
| US4663318A (en) | 1986-01-15 | 1987-05-05 | Bonnie Davis | Method of treating Alzheimer's disease |
| IT1190133B (it) | 1986-06-19 | 1988-02-10 | Chiesi Farma Spa | Derivati di acido valproico e di acido (e)-2-valproenoico,procedimento per la loro preparazione e relative composizioni farmaceutiche |
| US4816456A (en) | 1986-10-01 | 1989-03-28 | Summers William K | Administration of monoamine acridines in cholinergic neuronal deficit states |
| HU201906B (en) | 1987-03-04 | 1991-01-28 | Sandoz Ag | Process for producing phenyl-carbamate derivative and acid additional salts and pharmaceutical compositions containing them |
| FI91401C (fi) | 1987-03-17 | 1994-06-27 | Hoechst Roussel Pharma | Menetelmä terapeuttisesti aktiivisten substituoitujen 9-aminotetrahydroakriinien ja niille läheisten yhdisteiden valmistamiseksi |
| DE3709230A1 (de) | 1987-03-20 | 1988-10-06 | Desitin Arzneimittel Gmbh | Neues calciumsalz der valproinsaeure |
| IT1225462B (it) | 1987-04-03 | 1990-11-14 | Mediolanum Farmaceutici Srl | Sali organici di derivati della fisostigmina |
| US5002955A (en) | 1987-04-23 | 1991-03-26 | Hoechst-Roussel Pharmaceuticals Inc. | Fused heteroalkylene quinolinamines and use as cholinergic agents |
| AU632458B2 (en) | 1987-05-04 | 1993-01-07 | Bonnie Davis | Compounds for the treatment of alzheimer's disease |
| US5187165A (en) | 1987-05-15 | 1993-02-16 | Hoechst-Roussel Pharmaceuticals Inc. | Memory enhancing and analgesic 1,2,3a,8,8a-hexahydro-3a,8(and 1,3a,8)-di(and tri)methylpyrrolo[2,3-b]indoles |
| FI95572C (fi) | 1987-06-22 | 1996-02-26 | Eisai Co Ltd | Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi |
| JPS6422883A (en) | 1987-07-17 | 1989-01-25 | Sanwa Kagaku Kenkyusho Co | 1-pyrrolidine acetamide derivative, its salt, production thereof and prophylactic and remedial agent for cereral dysfunction containing said derivative and salt as active ingredient |
| ES2026198T3 (es) | 1987-07-22 | 1992-04-16 | Farvalsa Ag | Compuesto a base de acido valproico solido, estable a la humedad y metodo para su preparacion. |
| US4950658A (en) | 1988-12-06 | 1990-08-21 | Board Of Trustees Of Southern Illinois Univ. | Method of medical treatment of Alzheimer's disease |
| HUT53607A (en) | 1989-01-17 | 1990-11-28 | Hoffmann La Roche | Process for production of derivatives of cyclohexan-acetamid |
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2014
- 2014-03-14 CN CN201480023830.4A patent/CN105142623A/zh active Pending
- 2014-03-14 WO PCT/US2014/029362 patent/WO2014144801A1/en not_active Ceased
- 2014-03-14 AU AU2014228512A patent/AU2014228512A1/en not_active Abandoned
- 2014-03-14 JP JP2016503074A patent/JP6433482B2/ja active Active
- 2014-03-14 HK HK16106610.9A patent/HK1218623A1/zh unknown
- 2014-03-14 US US14/776,378 patent/US11160785B2/en not_active Expired - Fee Related
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| WO2014144801A1 (en) | 2014-09-18 |
| CN105142623A (zh) | 2015-12-09 |
| US11160785B2 (en) | 2021-11-02 |
| AU2020210168B2 (en) | 2021-09-16 |
| EP2968220A1 (en) | 2016-01-20 |
| AU2019201994A1 (en) | 2019-04-18 |
| JP2016514688A (ja) | 2016-05-23 |
| DK2968220T3 (da) | 2021-06-14 |
| JP2019206576A (ja) | 2019-12-05 |
| AU2020210168A1 (en) | 2020-08-13 |
| AU2014228512A1 (en) | 2015-10-01 |
| JP7084632B2 (ja) | 2022-06-15 |
| JP2021046438A (ja) | 2021-03-25 |
| CA2904767A1 (en) | 2014-09-18 |
| EP2968220A4 (en) | 2016-10-19 |
| US20160271108A1 (en) | 2016-09-22 |
| ES2881081T3 (es) | 2021-11-26 |
| HK1218623A1 (zh) | 2017-03-03 |
| JP6808679B2 (ja) | 2021-01-06 |
| JP2018131462A (ja) | 2018-08-23 |
| EP2968220B1 (en) | 2021-05-05 |
| JP6433482B2 (ja) | 2018-12-05 |
| HK1220364A1 (zh) | 2017-05-05 |
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