JP6359537B2 - 複素環エステル誘導体の調製プロセス - Google Patents
複素環エステル誘導体の調製プロセス Download PDFInfo
- Publication number
- JP6359537B2 JP6359537B2 JP2015526601A JP2015526601A JP6359537B2 JP 6359537 B2 JP6359537 B2 JP 6359537B2 JP 2015526601 A JP2015526601 A JP 2015526601A JP 2015526601 A JP2015526601 A JP 2015526601A JP 6359537 B2 JP6359537 B2 JP 6359537B2
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- viii
- present
- carbon monoxide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/0825—Preparations of compounds not comprising Si-Si or Si-cyano linkages
- C07F7/083—Syntheses without formation of a Si-C bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261680412P | 2012-08-07 | 2012-08-07 | |
| US61/680,412 | 2012-08-07 | ||
| PCT/US2013/053595 WO2014025675A1 (en) | 2012-08-07 | 2013-08-05 | Process for the preparation of heterocyclic ester derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015525796A JP2015525796A (ja) | 2015-09-07 |
| JP6359537B2 true JP6359537B2 (ja) | 2018-07-18 |
Family
ID=48985861
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015526601A Expired - Fee Related JP6359537B2 (ja) | 2012-08-07 | 2013-08-05 | 複素環エステル誘導体の調製プロセス |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9303046B2 (enExample) |
| EP (1) | EP2882757B1 (enExample) |
| JP (1) | JP6359537B2 (enExample) |
| CN (1) | CN104870454B (enExample) |
| AR (1) | AR092071A1 (enExample) |
| AU (1) | AU2013299922B2 (enExample) |
| ES (1) | ES2608628T3 (enExample) |
| IN (1) | IN2015DN00659A (enExample) |
| JO (1) | JO3185B1 (enExample) |
| TW (1) | TWI608009B (enExample) |
| UY (1) | UY34973A (enExample) |
| WO (1) | WO2014025675A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2882757B1 (en) * | 2012-08-07 | 2016-10-05 | Janssen Pharmaceutica, N.V. | Process for the preparation of heterocyclic ester derivatives |
| MX2019008230A (es) | 2017-01-10 | 2019-10-24 | Bayer Ag | Derivados heterociclicos como agentes de control de plagas. |
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| WO1996011932A1 (en) | 1994-10-14 | 1996-04-25 | Smithkline Beecham Plc | 2-(imidazol-4-yl)carbapeneme derivatives, intermediates thereof and use as antibacterials |
| CA2216943C (en) | 1995-04-19 | 2003-06-17 | Boston Scientific Limited | Drug release coated stent |
| US6117432A (en) | 1995-04-20 | 2000-09-12 | Societe D'exploitation De Produits Pour Les Industries Chimiques (S.E.P.P.I.C.) | Therapeutic composition comprising an antigen or an in vivo generator of a compound comprising an amino acid sequence |
| TW349948B (en) | 1995-10-31 | 1999-01-11 | Janssen Pharmaceutica Nv | Farnesyl transferase inhibiting 2-quinolone derivatives |
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| JP2001505548A (ja) | 1996-12-20 | 2001-04-24 | トヴァリシェストヴォ エス オグラニチェンノイ オトヴェトストヴェンノストジュ“タブジュファーム” | 凍結乾燥ハイドロクロライド−1β,10β−エポキシ−13−ジメチルアミノ−グアヤ−3(4)−エン−6,12−オリドの生成方法および装置 |
| UA59384C2 (uk) | 1996-12-20 | 2003-09-15 | Пфайзер, Інк. | Похідні сульфонамідів та амідів як агоністи простагландину, фармацевтична композиція та способи лікування на їх основі |
| TW591030B (en) | 1997-03-10 | 2004-06-11 | Janssen Pharmaceutica Nv | Farnesyl transferase inhibiting 1,8-annelated quinolinone derivatives substituted with N- or C-linked imidazoles |
| EP0977750B1 (en) | 1997-04-25 | 2007-07-04 | Janssen Pharmaceutica N.V. | Farnesyltransferase inhibiting quinazolinones |
| TW491872B (en) | 1997-05-27 | 2002-06-21 | Ciba Sc Holding Ag | Block oligomers containing l-hydrocarbyloxy-2,2,6,6-tetramethyl-4- piperidyl groups as stabilizers for lower polyolefin |
| US6100254A (en) | 1997-10-10 | 2000-08-08 | Board Of Regents, The University Of Texas System | Inhibitors of protein tyrosine kinases |
| PT1060619E (pt) | 1998-03-05 | 2002-11-29 | Formula One Administration Ltd | Sistema de comunicacao de dados |
| US6303654B1 (en) | 1998-03-12 | 2001-10-16 | Wisconsin Alumni Research Foundation | Acyclic monoterpenoid derivatives |
| WO2000001691A1 (en) | 1998-07-01 | 2000-01-13 | Merck & Co., Inc. | Process for making farnesyl-protein transferase inhibitors |
| WO2000002871A1 (en) | 1998-07-10 | 2000-01-20 | Merck & Co., Inc. | Novel angiogenesis inhibitors |
| CA2341739C (en) | 1998-08-27 | 2005-07-12 | Pfizer Products Inc. | Quinolin-2-one derivatives useful as anticancer agents |
| AP2001002079A0 (en) | 1998-08-27 | 2001-03-31 | Pfizer Prod Inc | Alkynyl-substituted quinolin-2-one derivatives useful as anticancer agents. |
| GB9824579D0 (en) | 1998-11-10 | 1999-01-06 | Novartis Ag | Organic compounds |
| CZ302374B6 (cs) | 1998-12-23 | 2011-04-20 | Janssen Pharmaceutica N.V. | Derivát 1,2-anelovaného chinolinu, zpusob a meziprodukt pro jeho prípravu a farmaceutický prostredek s jeho obsahem |
| AU779008C (en) | 1999-01-11 | 2005-06-30 | Princeton University | High affinity inhibitors for target validation and uses thereof |
| US7125875B2 (en) | 1999-04-15 | 2006-10-24 | Bristol-Myers Squibb Company | Cyclic protein tyrosine kinase inhibitors |
| PT1169038E (pt) | 1999-04-15 | 2012-10-26 | Bristol Myers Squibb Co | Inibidores cíclicos da proteína tirosina cinase |
| ES2223705T3 (es) | 1999-04-28 | 2005-03-01 | Board Of Regents, The University Of Texas System | Composiciones y metodos para el tratamiento de cancer mediante inhibi cion selectiva del vegf. |
| US6346625B1 (en) | 1999-06-23 | 2002-02-12 | Astrazeneca Ab | Protein kinase inhibitors |
| DE19962924A1 (de) | 1999-12-24 | 2001-07-05 | Bayer Ag | Substituierte Oxazolidinone und ihre Verwendung |
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| CN101340909B (zh) | 2005-10-18 | 2012-01-11 | 詹森药业有限公司 | 抑制flt3激酶的方法 |
| CA2649919C (en) | 2006-04-20 | 2019-06-18 | Janssen Pharmaceutica N.V. | Phenyl-or pyridinyl amides as inhibitors of protein tyrosine kinases |
| MX2008013531A (es) | 2006-04-20 | 2009-01-20 | Janssen Pharmaceutica Nv | Inhibidores de c-fms cinasa. |
| US8697716B2 (en) | 2006-04-20 | 2014-04-15 | Janssen Pharmaceutica Nv | Method of inhibiting C-KIT kinase |
| WO2007124316A1 (en) | 2006-04-20 | 2007-11-01 | Janssen Pharmaceutica N.V. | Heterocyclic compounds as inhibitors of c-fms kinase |
| CA2672960A1 (en) * | 2006-12-20 | 2008-07-10 | Schering Corporation | Novel jnk inhibitors |
| WO2008138184A1 (fr) * | 2007-05-14 | 2008-11-20 | Shanghai Hengrui Pharmaceutical Co.Ltd. | Dérivés de pyrrolo-azacycles, leur procédé de fabrication et leur utilisation en tant qu'inhibiteurs de protéine kinases |
| JO3240B1 (ar) | 2007-10-17 | 2018-03-08 | Janssen Pharmaceutica Nv | c-fms مثبطات كيناز |
| AU2008318656A1 (en) | 2007-10-31 | 2009-05-07 | Janssen Pharmaceutica N.V. | Biomarker for assessing response to FMS treatment |
| JP2012514044A (ja) * | 2008-12-30 | 2012-06-21 | ミレニアム ファーマシューティカルズ, インコーポレイテッド | Rafキナーゼ阻害剤として有用なヘテロアリール化合物 |
| JP2011026305A (ja) * | 2009-06-24 | 2011-02-10 | Daiichi Sankyo Co Ltd | イミダゾールカルボニル化合物を含有する医薬組成物 |
| RU2654068C1 (ru) * | 2009-09-28 | 2018-05-16 | Ф.Хоффманн-Ля Рош Аг | Бензоксазепиновые ингибиторы pi3 и способы применения |
| US9227971B2 (en) * | 2010-01-19 | 2016-01-05 | Merck Sharp & Dohme Corp. | Pyrazolo[1,5-a]pyrimidine compounds as mTOR inhibitors |
| EP2882757B1 (en) * | 2012-08-07 | 2016-10-05 | Janssen Pharmaceutica, N.V. | Process for the preparation of heterocyclic ester derivatives |
-
2013
- 2013-08-05 EP EP13748442.4A patent/EP2882757B1/en not_active Not-in-force
- 2013-08-05 CN CN201380041843.XA patent/CN104870454B/zh not_active Expired - Fee Related
- 2013-08-05 WO PCT/US2013/053595 patent/WO2014025675A1/en not_active Ceased
- 2013-08-05 IN IN659DEN2015 patent/IN2015DN00659A/en unknown
- 2013-08-05 JP JP2015526601A patent/JP6359537B2/ja not_active Expired - Fee Related
- 2013-08-05 AU AU2013299922A patent/AU2013299922B2/en not_active Ceased
- 2013-08-05 US US13/959,120 patent/US9303046B2/en active Active
- 2013-08-05 ES ES13748442.4T patent/ES2608628T3/es active Active
- 2013-08-06 TW TW102128025A patent/TWI608009B/zh not_active IP Right Cessation
- 2013-08-06 JO JOP/2013/0238A patent/JO3185B1/ar active
- 2013-08-07 AR ARP130102809A patent/AR092071A1/es not_active Application Discontinuation
- 2013-08-07 UY UY0001034973A patent/UY34973A/es not_active Application Discontinuation
-
2016
- 2016-02-23 US US15/051,052 patent/US20160168170A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| UY34973A (es) | 2014-02-28 |
| EP2882757B1 (en) | 2016-10-05 |
| AU2013299922B2 (en) | 2018-06-21 |
| ES2608628T3 (es) | 2017-04-12 |
| EP2882757A1 (en) | 2015-06-17 |
| AU2013299922A8 (en) | 2015-03-12 |
| HK1209753A1 (en) | 2016-04-08 |
| US9303046B2 (en) | 2016-04-05 |
| IN2015DN00659A (enExample) | 2015-06-26 |
| WO2014025675A1 (en) | 2014-02-13 |
| TWI608009B (zh) | 2017-12-11 |
| AR092071A1 (es) | 2015-03-18 |
| JP2015525796A (ja) | 2015-09-07 |
| TW201427986A (zh) | 2014-07-16 |
| AU2013299922A1 (en) | 2015-02-12 |
| HK1210617A1 (en) | 2016-04-29 |
| JO3185B1 (ar) | 2018-03-08 |
| US20160168170A1 (en) | 2016-06-16 |
| CN104870454A (zh) | 2015-08-26 |
| US20140046072A1 (en) | 2014-02-13 |
| CN104870454B (zh) | 2020-03-03 |
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