JP6306691B2 - ジカルボン酸を用いたエステル化セルロースエーテル - Google Patents

ジカルボン酸を用いたエステル化セルロースエーテル Download PDF

Info

Publication number
JP6306691B2
JP6306691B2 JP2016513984A JP2016513984A JP6306691B2 JP 6306691 B2 JP6306691 B2 JP 6306691B2 JP 2016513984 A JP2016513984 A JP 2016513984A JP 2016513984 A JP2016513984 A JP 2016513984A JP 6306691 B2 JP6306691 B2 JP 6306691B2
Authority
JP
Japan
Prior art keywords
cellulose ether
group
esterified cellulose
esterified
hpmc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2016513984A
Other languages
English (en)
Japanese (ja)
Other versions
JP2016519198A (ja
Inventor
リージェン・イン
マーク・エイ・ヒルマイヤー
スティーヴン・ジェイ・ギラウド
ロバート・エル・シュミット
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dow Global Technologies LLC
University of Minnesota System
Original Assignee
Dow Global Technologies LLC
University of Minnesota System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Global Technologies LLC, University of Minnesota System filed Critical Dow Global Technologies LLC
Publication of JP2016519198A publication Critical patent/JP2016519198A/ja
Application granted granted Critical
Publication of JP6306691B2 publication Critical patent/JP6306691B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B13/00—Preparation of cellulose ether-esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2016513984A 2013-05-14 2014-05-07 ジカルボン酸を用いたエステル化セルロースエーテル Expired - Fee Related JP6306691B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361822977P 2013-05-14 2013-05-14
US61/822,977 2013-05-14
PCT/US2014/037070 WO2014186185A1 (en) 2013-05-14 2014-05-07 Cellulose ethers esterified with dicarboxylic acids

Publications (2)

Publication Number Publication Date
JP2016519198A JP2016519198A (ja) 2016-06-30
JP6306691B2 true JP6306691B2 (ja) 2018-04-04

Family

ID=50977076

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016513984A Expired - Fee Related JP6306691B2 (ja) 2013-05-14 2014-05-07 ジカルボン酸を用いたエステル化セルロースエーテル

Country Status (7)

Country Link
US (1) US9890221B2 (enExample)
EP (1) EP2997046B1 (enExample)
JP (1) JP6306691B2 (enExample)
KR (1) KR20160006788A (enExample)
CN (1) CN105164162B (enExample)
BR (1) BR112015024522A8 (enExample)
WO (1) WO2014186185A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6683561B2 (ja) * 2016-07-12 2020-04-22 信越化学工業株式会社 腸溶性硬カプセル用組成物及び腸溶性硬カプセルの製造方法
CN112704671B (zh) * 2020-12-28 2022-04-19 普洛药业股份有限公司 一种阿莫西林克拉维酸钾胶囊及其制备方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4226981A (en) 1977-09-28 1980-10-07 Shin-Etsu Chemical Co., Ltd. Ether-ester derivatives of cellulose and their applications
DE2917104A1 (de) 1979-04-27 1980-11-06 Hoechst Ag Verfahren zur viskositaetserniedrigung von celluloseethern durch ozon und seine verwendung
JPS607492B2 (ja) * 1979-04-28 1985-02-25 信越化学工業株式会社 腸溶性カプセル
JPS5632424A (en) * 1979-08-27 1981-04-01 Shin Etsu Chem Co Ltd Preparation of formed enteric product
US4365060A (en) * 1979-04-28 1982-12-21 Shin-Etsu Chemical Co. Ltd. Enterosoluble capsules
JPS6225101A (ja) 1985-07-24 1987-02-03 Shin Etsu Chem Co Ltd 低重合度セルロ−スエ−テルの製造方法
JPS6281402A (ja) 1985-10-07 1987-04-14 Shin Etsu Chem Co Ltd セルロ−スエ−テル酸性ジカルボン酸エステルの製造方法
DE3620991A1 (de) 1986-06-23 1988-01-14 Henkel Kgaa Wasserloesliche alkenyl- oder alkylbernsteinsaeureester enthaltende celluloseether
DE4404840A1 (de) * 1994-02-16 1995-08-17 Wolff Walsrode Ag Thermoplastische biologisch abbaubare Polysaccharidderivate, Verfahren zu ihrer Herstellung und ihre Verwendung
DE19529409A1 (de) 1995-08-10 1997-02-13 Wolff Walsrode Ag Maleinsäureadditionsproduktgruppen enthaltende, thermoplastische und biologisch abbaubare Polysaccharidester/-etherester
EP0872233A1 (en) 1997-04-14 1998-10-21 Janssen Pharmaceutica N.V. Antiretroviral compositions with improved bioavailability
US6261218B1 (en) 1998-12-01 2001-07-17 The Dow Chemical Company Process and apparatus for making low molecular weight cellulose ethers
WO2000078285A1 (en) * 1999-06-18 2000-12-28 University Of Medicine And Dentistry Of New Jersey Controlled release of therapeutics by in-situ entrapment by matrix cross-linking
US20020076443A1 (en) * 2000-06-19 2002-06-20 Stanley Stein Multiple phase cross-linked compositions and uses thereof
DE10141680B4 (de) 2001-08-25 2004-02-26 Clariant Gmbh Verfahren zur Herstellung niederviskoser Celluloseether durch sauer-oxidativen Abbau von gemahlenen und getrockneten Celluloseethern
JP2003073443A (ja) * 2001-08-31 2003-03-12 Hiroshi Takimoto 生分解性高吸水性樹脂
JP2003160694A (ja) * 2001-11-28 2003-06-03 Hiroshi Takimoto 生分解性組成物
MXPA06013891A (es) 2004-05-28 2007-01-26 Pfizer Prod Inc Composiciones farmaceuticas con comportamiento potenciado.
EP2325247B1 (en) 2007-11-09 2014-10-08 Dow Global Technologies LLC Cellulose ether coating compositions and method
CN101855247B (zh) 2007-11-09 2013-03-20 联合碳化化学品及塑料技术公司 制备非常低粘度的纤维素醚的方法和产品
CN102933615B (zh) * 2010-06-08 2015-08-12 陶氏环球技术有限责任公司 制备粒状可逆交联的聚合物材料的方法
JP5792807B2 (ja) 2010-06-14 2015-10-14 ダウ グローバル テクノロジーズ エルエルシー アセテートおよびサクシネートの置換が向上されたヒドロキシプロピルメチルセルロースアセテートサクシネート
WO2013154607A1 (en) * 2012-04-11 2013-10-17 Dow Global Technologies Llc Esterified cellulose ethers having a specific substituent distribution
CN102807625A (zh) * 2012-08-23 2012-12-05 浙江中维药业有限公司 一种醋酸羟丙甲纤维素琥珀酸酯的制备方法

Also Published As

Publication number Publication date
CN105164162B (zh) 2017-11-28
EP2997046A1 (en) 2016-03-23
US9890221B2 (en) 2018-02-13
US20160289344A1 (en) 2016-10-06
BR112015024522A8 (pt) 2019-12-10
CN105164162A (zh) 2015-12-16
JP2016519198A (ja) 2016-06-30
WO2014186185A1 (en) 2014-11-20
KR20160006788A (ko) 2016-01-19
EP2997046B1 (en) 2019-09-25
BR112015024522A2 (enExample) 2017-08-22

Similar Documents

Publication Publication Date Title
JP6321688B2 (ja) 低粘度の新規エステル化セルロースエーテル
JP6334574B2 (ja) 新規の超高分子量のエステル化セルロースエーテル
KR102110119B1 (ko) 저점도 및 고분자량의 신규한 에스테르화된 셀룰로스 에테르
JP6133969B2 (ja) 特定の置換基分布を有するエステル化セルロースエーテル
KR102138545B1 (ko) 고분자량 및 높은 균일성을 갖는 신규한 에스테르화된 셀룰로즈 에테르
JP6420520B2 (ja) 新規の高分子量及び高均一性のエステル化セルロースエーテル
JP6267239B2 (ja) 極めて低粘度の新規エステル化セルロースエーテル
JP6356923B2 (ja) 水溶性エステル化セルロースエーテル
JP6371482B2 (ja) エステル化セルロースエーテルの水溶液
US9890221B2 (en) Cellulose ethers esterified with dicarboxylic acid
JP2016532720A (ja) 有機液体希釈剤及び特定のヒドロキシアルキルメチルセルロースを含む組成物

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20151117

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20160107

RD02 Notification of acceptance of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7422

Effective date: 20160107

RD03 Notification of appointment of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7423

Effective date: 20160107

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20160502

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20160629

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20170502

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20171205

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20180122

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20180206

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20180308

R150 Certificate of patent or registration of utility model

Ref document number: 6306691

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

LAPS Cancellation because of no payment of annual fees