JP6187255B2 - 癌の治療及び/又は予防用医薬組成物 - Google Patents

癌の治療及び/又は予防用医薬組成物 Download PDF

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JP6187255B2
JP6187255B2 JP2013512276A JP2013512276A JP6187255B2 JP 6187255 B2 JP6187255 B2 JP 6187255B2 JP 2013512276 A JP2013512276 A JP 2013512276A JP 2013512276 A JP2013512276 A JP 2013512276A JP 6187255 B2 JP6187255 B2 JP 6187255B2
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antibody
cancer
caprin
seq
human
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JPWO2013125636A1 (ja
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小林 真一
真一 小林
文義 岡野
文義 岡野
孝則 齋藤
孝則 齋藤
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Toray Industries Inc
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732Antibody-dependent cellular cytotoxicity [ADCC]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2013512276A 2012-02-21 2013-02-21 癌の治療及び/又は予防用医薬組成物 Active JP6187255B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2012035484 2012-02-21
JP2012035484 2012-02-21
PCT/JP2013/054337 WO2013125636A1 (ja) 2012-02-21 2013-02-21 癌の治療及び/又は予防用医薬組成物

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JPWO2013125636A1 JPWO2013125636A1 (ja) 2015-07-30
JP6187255B2 true JP6187255B2 (ja) 2017-08-30

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US (1) US9273130B2 (en:Method)
EP (1) EP2818482B1 (en:Method)
JP (1) JP6187255B2 (en:Method)
KR (1) KR102009238B1 (en:Method)
CN (1) CN104169303B (en:Method)
AU (1) AU2013223143B2 (en:Method)
CA (1) CA2864864C (en:Method)
DK (1) DK2818482T3 (en:Method)
ES (1) ES2739612T3 (en:Method)
HU (1) HUE044611T2 (en:Method)
IN (1) IN2014KN01713A (en:Method)
MX (1) MX360208B (en:Method)
PL (1) PL2818482T3 (en:Method)
PT (1) PT2818482T (en:Method)
RU (1) RU2632645C2 (en:Method)
WO (1) WO2013125636A1 (en:Method)

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CA2864864C (en) 2020-05-12
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MX2014009748A (es) 2014-11-14
KR102009238B1 (ko) 2019-08-09
CN104169303A (zh) 2014-11-26
WO2013125636A1 (ja) 2013-08-29
AU2013223143A1 (en) 2014-09-11
PL2818482T3 (pl) 2019-11-29
CA2864864A1 (en) 2013-08-29
RU2014138040A (ru) 2016-04-10
MX360208B (es) 2018-10-24
US20150004171A1 (en) 2015-01-01
HUE044611T2 (hu) 2019-11-28
PT2818482T (pt) 2019-08-06
EP2818482B1 (en) 2019-05-22
CN104169303B (zh) 2018-05-29
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JPWO2013125636A1 (ja) 2015-07-30
EP2818482A4 (en) 2015-10-07
KR20140130668A (ko) 2014-11-11
IN2014KN01713A (en:Method) 2015-10-23
ES2739612T3 (es) 2020-02-03
RU2632645C2 (ru) 2017-10-06
AU2013223143B2 (en) 2017-12-21
BR112014021101A2 (pt) 2022-03-22

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