JP6163429B2 - 神経疾患免疫治療のための方法及び組成物 - Google Patents

神経疾患免疫治療のための方法及び組成物 Download PDF

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JP6163429B2
JP6163429B2 JP2013538846A JP2013538846A JP6163429B2 JP 6163429 B2 JP6163429 B2 JP 6163429B2 JP 2013538846 A JP2013538846 A JP 2013538846A JP 2013538846 A JP2013538846 A JP 2013538846A JP 6163429 B2 JP6163429 B2 JP 6163429B2
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antibody
hvr
amino acid
bace1
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JP2014502150A5 (enExample
JP2014502150A (ja
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ジャスビンダル アトウォル，
ジャスビンダル アトウォル，
ヨンメイ チェン，
ヨンメイ チェン，
セシリア プイ チー チウ，
セシリア プイ チー チウ，
ロバート エー． ラザロ，
ロバート エー． ラザロ，
ウエイルー ワン，
ウエイルー ワン，
ライアン ジェー． ワッツ，
ライアン ジェー． ワッツ，
イェン ウー，
イェン ウー，
インナン チャン，
インナン チャン，
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Genentech Inc
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    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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JP2013538846A 2010-11-10 2011-11-09 神経疾患免疫治療のための方法及び組成物 Active JP6163429B2 (ja)

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US45664210P 2010-11-10 2010-11-10
US61/456,642 2010-11-10
US41831010P 2010-11-30 2010-11-30
US61/418,310 2010-11-30
US41885010P 2010-12-01 2010-12-01
US61/418,850 2010-12-01
US201061426425P 2010-12-22 2010-12-22
US61/426,425 2010-12-22
PCT/US2011/059964 WO2012064836A1 (en) 2010-11-10 2011-11-09 Methods and compositions for neural disease immunotherapy

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CN106084057A (zh) * 2016-06-13 2016-11-09 东北师范大学 Bace1剪切型高效价抗体的制备及应用
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CN107475260B (zh) * 2017-09-08 2020-12-04 东北师范大学 抑制大脑中Aβ累积的BACE1亚型的功能研发及应用
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CN113227131B (zh) 2018-12-20 2025-03-04 豪夫迈·罗氏有限公司 经修饰的抗体Fc及其使用方法
CN119033928A (zh) * 2019-05-01 2024-11-29 纽约大学 抗半乳糖凝集素-9抗体及其用途
US20250304677A1 (en) 2022-07-04 2025-10-02 Vib Vzw Blood-Cerebrospinal Fluid Barrier Crossing Antibodies
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