JP6156144B2 - 親和性複合体に対する抗体 - Google Patents

親和性複合体に対する抗体 Download PDF

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Publication number
JP6156144B2
JP6156144B2 JP2013534624A JP2013534624A JP6156144B2 JP 6156144 B2 JP6156144 B2 JP 6156144B2 JP 2013534624 A JP2013534624 A JP 2013534624A JP 2013534624 A JP2013534624 A JP 2013534624A JP 6156144 B2 JP6156144 B2 JP 6156144B2
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antibody
vitamin
affinity complex
complex
affinity
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Japanese (ja)
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JPWO2013042426A1 (ja
Inventor
和也 小見
和也 小見
豪 安藤
豪 安藤
内田　好昭
好昭 内田
勝利 碁石
勝利 碁石
麻子 岡
麻子 岡
貴志 白川
貴志 白川
拓弥 佐久
拓弥 佐久
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Fujirebio Inc
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Fujirebio Inc
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/743—Steroid hormones
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/78—Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/32—Immunoglobulins specific features characterized by aspects of specificity or valency specific for a neo-epitope on a complex, e.g. antibody-antigen or ligand-receptor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Endocrinology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2013534624A 2011-09-21 2012-07-04 親和性複合体に対する抗体 Active JP6156144B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2011206162 2011-09-21
JP2011206162 2011-09-21
JP2012006359 2012-01-16
JP2012006359 2012-01-16
PCT/JP2012/067062 WO2013042426A1 (ja) 2011-09-21 2012-07-04 親和性複合体に対する抗体

Publications (2)

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JPWO2013042426A1 JPWO2013042426A1 (ja) 2015-03-26
JP6156144B2 true JP6156144B2 (ja) 2017-07-05

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JP2013534624A Active JP6156144B2 (ja) 2011-09-21 2012-07-04 親和性複合体に対する抗体

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US (1) US9599608B2 (https=)
EP (1) EP2759551B1 (https=)
JP (1) JP6156144B2 (https=)
KR (1) KR101720394B1 (https=)
CN (1) CN103827145A (https=)
AU (1) AU2012310880B2 (https=)
BR (1) BR112014006405A2 (https=)
CA (1) CA2849274C (https=)
IL (1) IL231404A0 (https=)
IN (1) IN2014CN02113A (https=)
RU (1) RU2014115676A (https=)
TW (1) TW201313743A (https=)
WO (1) WO2013042426A1 (https=)

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US10983136B2 (en) 2013-01-28 2021-04-20 Diasorin S.P.A. Use of 1,25-dihydroxyvitamin D values in ratio with PTH as a prognostic biomarker
US11261257B2 (en) 2013-01-28 2022-03-01 Diasorin S.P.A. Methods for detecting 1,25-dihydroxyvitamin D and related antibodies
EP2955516B1 (en) 2013-02-06 2017-06-28 Fujirebio Inc. Vitamin d measurement method and measurement kit
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CN106244562B (zh) * 2016-05-20 2019-07-23 杭州奥泰生物技术股份有限公司 杂交瘤细胞株及其分泌的抗25羟基维生素d3单克隆抗体和应用
ES2878036T3 (es) * 2016-07-29 2021-11-18 Diazyme Laboratories Inc Métodos y composiciones para el análisis de vitamina D
US11939379B2 (en) 2017-05-19 2024-03-26 The Regents Of The University Of California Antibody chemically induced dimerizer (AbCID) as molecular switches for regulating cellular therapies
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CN114746754A (zh) * 2019-11-20 2022-07-12 东曹株式会社 使用抗免疫复合物抗体的测定方法
JP7683188B2 (ja) * 2019-11-29 2025-05-27 東ソー株式会社 抗イムノコンプレックス抗体を用いた測定法
CN113125696B (zh) * 2019-12-31 2024-03-26 科美博阳诊断技术(上海)有限公司 一种雌二醇均相化学发光检测试剂盒及其应用

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Also Published As

Publication number Publication date
WO2013042426A1 (ja) 2013-03-28
CA2849274A1 (en) 2013-03-28
IL231404A0 (en) 2014-04-30
EP2759551A4 (en) 2015-03-04
US20150037813A1 (en) 2015-02-05
AU2012310880B2 (en) 2015-12-03
KR101720394B1 (ko) 2017-03-27
BR112014006405A2 (pt) 2017-04-04
IN2014CN02113A (https=) 2015-05-29
EP2759551B1 (en) 2019-05-22
US9599608B2 (en) 2017-03-21
KR20140044940A (ko) 2014-04-15
TW201313743A (zh) 2013-04-01
JPWO2013042426A1 (ja) 2015-03-26
RU2014115676A (ru) 2015-10-27
AU2012310880A1 (en) 2014-04-10
CN103827145A (zh) 2014-05-28
EP2759551A1 (en) 2014-07-30
CA2849274C (en) 2018-12-04

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