JP6114500B2 - 間葉幹細胞及びその使用法 - Google Patents

間葉幹細胞及びその使用法 Download PDF

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JP6114500B2
JP6114500B2 JP2012058539A JP2012058539A JP6114500B2 JP 6114500 B2 JP6114500 B2 JP 6114500B2 JP 2012058539 A JP2012058539 A JP 2012058539A JP 2012058539 A JP2012058539 A JP 2012058539A JP 6114500 B2 JP6114500 B2 JP 6114500B2
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cells
mesenchymal stem
stem cells
mscs
cell
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Japanese (ja)
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JP2012176948A (ja
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ピッテンジャー，マーク，エフ．
アガワル，スディープタ
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メゾブラスト・インターナショナル・ソシエテ・ア・レスポンサビリテ・リミテ
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2012058539A 2004-03-22 2012-03-15 間葉幹細胞及びその使用法 Expired - Lifetime JP6114500B2 (ja)

Applications Claiming Priority (2)

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US55511804P 2004-03-22 2004-03-22
US60/555,118 2004-03-22

Related Parent Applications (1)

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JP2007505005A Division JP2007530543A (ja) 2004-03-22 2005-03-15 間葉幹細胞及びその使用法

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2014241859A Division JP5997237B2 (ja) 2004-03-22 2014-11-28 間葉幹細胞及びその使用法
JP2017003854A Division JP6382360B2 (ja) 2004-03-22 2017-01-13 間葉幹細胞及びその使用法

Publications (2)

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JP2012176948A JP2012176948A (ja) 2012-09-13
JP6114500B2 true JP6114500B2 (ja) 2017-04-12

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Family Applications (8)

Application Number Title Priority Date Filing Date
JP2012058539A Expired - Lifetime JP6114500B2 (ja) 2004-03-22 2012-03-15 間葉幹細胞及びその使用法
JP2014241859A Expired - Lifetime JP5997237B2 (ja) 2004-03-22 2014-11-28 間葉幹細胞及びその使用法
JP2017003854A Expired - Lifetime JP6382360B2 (ja) 2004-03-22 2017-01-13 間葉幹細胞及びその使用法
JP2017155229A Expired - Lifetime JP6757300B2 (ja) 2004-03-22 2017-08-10 間葉幹細胞及びその使用法
JP2018190636A Expired - Lifetime JP6757383B2 (ja) 2004-03-22 2018-10-09 間葉幹細胞及びその使用法
JP2020047240A Expired - Lifetime JP7033159B2 (ja) 2004-03-22 2020-03-18 間葉幹細胞及びその使用法
JP2021140167A Expired - Lifetime JP7546239B2 (ja) 2004-03-22 2021-08-30 間葉幹細胞及びその使用法
JP2023023996A Pending JP2023065486A (ja) 2004-03-22 2023-02-20 間葉幹細胞及びその使用法

Family Applications After (7)

Application Number Title Priority Date Filing Date
JP2014241859A Expired - Lifetime JP5997237B2 (ja) 2004-03-22 2014-11-28 間葉幹細胞及びその使用法
JP2017003854A Expired - Lifetime JP6382360B2 (ja) 2004-03-22 2017-01-13 間葉幹細胞及びその使用法
JP2017155229A Expired - Lifetime JP6757300B2 (ja) 2004-03-22 2017-08-10 間葉幹細胞及びその使用法
JP2018190636A Expired - Lifetime JP6757383B2 (ja) 2004-03-22 2018-10-09 間葉幹細胞及びその使用法
JP2020047240A Expired - Lifetime JP7033159B2 (ja) 2004-03-22 2020-03-18 間葉幹細胞及びその使用法
JP2021140167A Expired - Lifetime JP7546239B2 (ja) 2004-03-22 2021-08-30 間葉幹細胞及びその使用法
JP2023023996A Pending JP2023065486A (ja) 2004-03-22 2023-02-20 間葉幹細胞及びその使用法

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JP (8) JP6114500B2 (enExample)
AT (1) ATE556134T1 (enExample)
CA (3) CA2934682C (enExample)
ES (7) ES2544689T3 (enExample)
TR (1) TR201901268T4 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2934682C (en) * 2004-03-22 2021-12-07 Mesoblast International Sarl Mesenchymal stem cells and uses therefor
EP2298861B1 (en) * 2004-03-22 2017-09-13 Mesoblast International Sàrl Mesenchymal stem cells and uses therefor
EP2849765A4 (en) * 2012-05-16 2015-12-02 Univ Johns Hopkins STEM CELLS AS INDIVIDUALIZED MATERNAL THERAPY FOR THE PREVENTION OF EARLY BIRTHS
JP2016210730A (ja) * 2015-05-08 2016-12-15 上田　実 医薬組成物及びその製造方法並びに医薬品
WO2018092769A1 (ja) 2016-11-15 2018-05-24 株式会社カネカ 胎児付属物に由来する間葉系幹細胞を含む細胞集団とその製造方法、及び医薬組成物
CN112004923A (zh) 2017-11-22 2020-11-27 迈索布拉斯特国际有限公司 细胞组合物及治疗方法
WO2019132026A1 (ja) 2017-12-28 2019-07-04 株式会社カネカ 接着性幹細胞を含む細胞集団とその製造方法、及び医薬組成物
EP3984596A4 (en) 2019-06-14 2023-06-21 Kaneka Corporation POPULATION OF CELLS COMPRISING MESENCHYMATOUS CELLS, PHARMACEUTICAL COMPOSITION COMPRISING THEM AND METHOD FOR PRODUCTION THEREOF
EP4013856A1 (en) * 2019-08-15 2022-06-22 NextCell Pharma AB Allogeneic composition for treatment of cns disorders
CN113813288B (zh) * 2021-08-11 2024-02-13 谢岩 间充质干细胞及包含其的组合物用于制备治疗烧伤难愈创面的药物的用途

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0651641B2 (ja) * 1983-08-29 1994-07-06 株式会社ミドリ十字 ガンマ・インターフェロン組成物
JPH01501792A (ja) * 1986-03-17 1989-06-22 シェリング・コーポレーション γ型インターフェロンによる癌の治療
CA2191733A1 (en) * 1994-06-07 1995-12-21 Daniel A. Vallera Methods for inhibiting antigen specific t cell responses
US6497875B1 (en) * 1996-04-26 2002-12-24 Case Western Reserve University Multilayer skin or dermal equivalent having a layer containing mesenchymal stem cells
CA2320040C (en) * 1998-03-18 2007-05-22 Osiris Therapeutics, Inc. Mesenchymal stem cells for prevention and treatment of immune responses in transplantation
US6368636B1 (en) * 1998-03-18 2002-04-09 Osiris Therapeutics, Inc. Mesenchymal stem cells for prevention and treatment of immune responses in transplantation
US6797269B2 (en) * 1998-04-03 2004-09-28 Osiris Therapeutics, Inc. Mesenchymal stem cells as immunosuppressants
AU2001229254B2 (en) * 2000-01-19 2006-07-27 Gill, Parkash S. Pharmaceutical compositions and methods of treatment based on VEGF antisense oligonucleotides
ES2353061T5 (es) * 2000-04-25 2014-04-07 Osiris Therapeutics, Inc. Reparación de articulaciones utilizando células madre mesenquimatosas
MXPA04007426A (es) * 2002-02-01 2004-10-11 Schering Corp Usos de citosina de mamifero; reactivos relacionados.
JP3897343B2 (ja) * 2002-08-01 2007-03-22 株式会社林原生物化学研究所 免疫担当細胞においてインターフェロン−γの産生を誘導する蛋白質
WO2004052177A2 (en) * 2002-12-05 2004-06-24 Case Western Reserve University Cell-based therapies for ischemia
CA2934682C (en) * 2004-03-22 2021-12-07 Mesoblast International Sarl Mesenchymal stem cells and uses therefor
EP2298861B1 (en) * 2004-03-22 2017-09-13 Mesoblast International Sàrl Mesenchymal stem cells and uses therefor

Also Published As

Publication number Publication date
CA2868733A1 (en) 2005-10-06
ES2645018T3 (es) 2017-12-01
ES2385450T3 (es) 2012-07-25
JP2019014747A (ja) 2019-01-31
JP2012176948A (ja) 2012-09-13
JP6382360B2 (ja) 2018-08-29
ES2643076T3 (es) 2017-11-21
ATE556134T1 (de) 2012-05-15
TR201901268T4 (tr) 2019-02-21
JP2015061862A (ja) 2015-04-02
ES2544689T3 (es) 2015-09-02
JP6757383B2 (ja) 2020-09-16
JP2017080507A (ja) 2017-05-18
ES2708627T3 (es) 2019-04-10
ES2643030T3 (es) 2017-11-21
HK1205531A1 (en) 2015-12-18
ES2657382T5 (es) 2021-07-12
JP5997237B2 (ja) 2016-09-28
CA3135582A1 (en) 2005-10-06
CA2934682C (en) 2021-12-07
CA2868733C (en) 2019-12-17
ES2657382T3 (es) 2018-03-05
JP2018009002A (ja) 2018-01-18
JP7546239B2 (ja) 2024-09-06
JP2021191771A (ja) 2021-12-16
JP2020111591A (ja) 2020-07-27
JP7033159B2 (ja) 2022-03-09
CA2934682A1 (en) 2005-10-06
JP6757300B2 (ja) 2020-09-16
JP2023065486A (ja) 2023-05-12
HK1205677A1 (en) 2015-12-24

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