CA3135582A1 - Mesenchymal stem cells and uses therefor - Google Patents

Mesenchymal stem cells and uses therefor Download PDF

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Publication number
CA3135582A1
CA3135582A1 CA3135582A CA3135582A CA3135582A1 CA 3135582 A1 CA3135582 A1 CA 3135582A1 CA 3135582 A CA3135582 A CA 3135582A CA 3135582 A CA3135582 A CA 3135582A CA 3135582 A1 CA3135582 A1 CA 3135582A1
Authority
CA
Canada
Prior art keywords
mesenchymal stem
stem cells
cells
use according
cultured
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3135582A
Other languages
English (en)
French (fr)
Inventor
Mark F. Pittenger
Sudeepta Aggarwal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mesoblast International SARL
Original Assignee
Mesoblast International SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mesoblast International SARL filed Critical Mesoblast International SARL
Publication of CA3135582A1 publication Critical patent/CA3135582A1/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • C12N5/0663Bone marrow mesenchymal stem cells (BM-MSC)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA3135582A 2004-03-22 2005-03-15 Mesenchymal stem cells and uses therefor Pending CA3135582A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US55511804P 2004-03-22 2004-03-22
US60/555,118 2004-03-22
CA2934682A CA2934682C (en) 2004-03-22 2005-03-15 Mesenchymal stem cells and uses therefor

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA2934682A Division CA2934682C (en) 2004-03-22 2005-03-15 Mesenchymal stem cells and uses therefor

Publications (1)

Publication Number Publication Date
CA3135582A1 true CA3135582A1 (en) 2005-10-06

Family

ID=46060822

Family Applications (3)

Application Number Title Priority Date Filing Date
CA3135582A Pending CA3135582A1 (en) 2004-03-22 2005-03-15 Mesenchymal stem cells and uses therefor
CA2868733A Expired - Lifetime CA2868733C (en) 2004-03-22 2005-03-15 Mesenchymal stem cells for treating inflammation
CA2934682A Expired - Lifetime CA2934682C (en) 2004-03-22 2005-03-15 Mesenchymal stem cells and uses therefor

Family Applications After (2)

Application Number Title Priority Date Filing Date
CA2868733A Expired - Lifetime CA2868733C (en) 2004-03-22 2005-03-15 Mesenchymal stem cells for treating inflammation
CA2934682A Expired - Lifetime CA2934682C (en) 2004-03-22 2005-03-15 Mesenchymal stem cells and uses therefor

Country Status (5)

Country Link
JP (8) JP6114500B2 (enExample)
AT (1) ATE556134T1 (enExample)
CA (3) CA3135582A1 (enExample)
ES (7) ES2544689T3 (enExample)
TR (1) TR201901268T4 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2544689T3 (es) * 2004-03-22 2015-09-02 Mesoblast International Sàrl Células madre mesenquimales y usos de las mismas
WO2005093044A1 (en) * 2004-03-22 2005-10-06 Osiris Therapeutics, Inc. Mesenchymal stem cells and uses therefor
WO2014098960A2 (en) * 2012-05-16 2014-06-26 The Johns Hopkins University Stem cells as an individualized maternal therapy for prevention of prematurity
JP2016210730A (ja) * 2015-05-08 2016-12-15 上田 実 医薬組成物及びその製造方法並びに医薬品
US11401502B2 (en) 2016-11-15 2022-08-02 Kaneka Corporation Cell population comprising mesenchymal stem cells derived from fetal appendage, method for producing the same, and pharmaceutical composition
AU2018372631B2 (en) 2017-11-22 2025-06-05 Mesoblast International Sarl Cellular compositions and methods of treatment I
WO2019132026A1 (ja) 2017-12-28 2019-07-04 株式会社カネカ 接着性幹細胞を含む細胞集団とその製造方法、及び医薬組成物
EP3984596A4 (en) 2019-06-14 2023-06-21 Kaneka Corporation POPULATION OF CELLS COMPRISING MESENCHYMATOUS CELLS, PHARMACEUTICAL COMPOSITION COMPRISING THEM AND METHOD FOR PRODUCTION THEREOF
CA3148582A1 (en) * 2019-08-15 2021-02-18 Nextcell Pharma Ab Allogeneic composition for treatment of cns disorders
CN113813288B (zh) * 2021-08-11 2024-02-13 谢岩 间充质干细胞及包含其的组合物用于制备治疗烧伤难愈创面的药物的用途

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0651641B2 (ja) * 1983-08-29 1994-07-06 株式会社ミドリ十字 ガンマ・インターフェロン組成物
WO1987005518A1 (en) * 1986-03-17 1987-09-24 Schering Corporation Treatment of cancers with gamma interferon
AU2701895A (en) * 1994-06-07 1996-01-05 Regents Of The University Of Minnesota Methods for inhibiting antigen specific t cell responses
JP2000508922A (ja) * 1996-04-26 2000-07-18 ケース ウエスターン リザーブ ユニバーシティ 間葉幹細胞を用いる皮膚再生
US6368636B1 (en) * 1998-03-18 2002-04-09 Osiris Therapeutics, Inc. Mesenchymal stem cells for prevention and treatment of immune responses in transplantation
DE69929681T2 (de) * 1998-03-18 2006-10-26 Osiris Therapeutics, Inc. Mesenchymale stammzellen für die prävention und behandlung von immunantworten bei transplantationen
JP2002510655A (ja) * 1998-04-03 2002-04-09 オシリス セラピューティクス,インコーポレイテッド 免疫抑制剤としての間葉幹細胞によるt細胞応答を阻害する方法とその利用
AU2925401A (en) * 2000-01-19 2001-07-31 Parkash S Gill Methods and compositions for antisense vegf oligonucleotides
DE60143517D1 (de) * 2000-04-25 2011-01-05 Osiris Therapeutics Inc Wiederherstellung der gelenken mit mesenchymalen stammzellen
MXPA04007426A (es) * 2002-02-01 2004-10-11 Schering Corp Usos de citosina de mamifero; reactivos relacionados.
JP3897343B2 (ja) * 2002-08-01 2007-03-22 株式会社林原生物化学研究所 免疫担当細胞においてインターフェロン−γの産生を誘導する蛋白質
EP1583422B1 (en) * 2002-12-05 2016-03-30 Case Western Reserve University Cell-based therapies for ischemia
WO2005093044A1 (en) * 2004-03-22 2005-10-06 Osiris Therapeutics, Inc. Mesenchymal stem cells and uses therefor
ES2544689T3 (es) * 2004-03-22 2015-09-02 Mesoblast International Sàrl Células madre mesenquimales y usos de las mismas

Also Published As

Publication number Publication date
JP2019014747A (ja) 2019-01-31
JP6382360B2 (ja) 2018-08-29
JP2017080507A (ja) 2017-05-18
CA2868733A1 (en) 2005-10-06
CA2934682C (en) 2021-12-07
CA2934682A1 (en) 2005-10-06
JP6757300B2 (ja) 2020-09-16
ES2657382T3 (es) 2018-03-05
JP2015061862A (ja) 2015-04-02
HK1205677A1 (en) 2015-12-24
ATE556134T1 (de) 2012-05-15
ES2708627T3 (es) 2019-04-10
JP5997237B2 (ja) 2016-09-28
JP6114500B2 (ja) 2017-04-12
ES2643030T3 (es) 2017-11-21
JP7546239B2 (ja) 2024-09-06
JP2012176948A (ja) 2012-09-13
JP2018009002A (ja) 2018-01-18
JP2021191771A (ja) 2021-12-16
JP2023065486A (ja) 2023-05-12
JP7033159B2 (ja) 2022-03-09
ES2643076T3 (es) 2017-11-21
HK1205531A1 (en) 2015-12-18
ES2385450T3 (es) 2012-07-25
JP2020111591A (ja) 2020-07-27
CA2868733C (en) 2019-12-17
TR201901268T4 (tr) 2019-02-21
ES2657382T5 (es) 2021-07-12
JP6757383B2 (ja) 2020-09-16
ES2544689T3 (es) 2015-09-02
ES2645018T3 (es) 2017-12-01

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Legal Events

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EEER Examination request

Effective date: 20211022

EEER Examination request

Effective date: 20211022

EEER Examination request

Effective date: 20211022

EEER Examination request

Effective date: 20211022

EEER Examination request

Effective date: 20211022